The South-East Asian Transgender Health Cohort

NCT ID: NCT05454579

Last Updated: 2024-11-25

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Total Enrollment

450 participants

Study Classification

OBSERVATIONAL

Study Start Date

2022-12-02

Study Completion Date

2026-05-30

Brief Summary

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This is a prospective observational cohort study that will enroll 300 HIV-negative transgender people and 150 transgender people living with HIV from 4 community health centers in Thailand, Vietnam, and the Philippines. Each participant will be followed-up until the completion of 24 months.

Detailed Description

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This prospective observational cohort study will longitudinally track physical (e.g. HIV/STI, sexual risk behavior, gender affirmation, clinical information, cardiovascular health, medical history) and mental health (e.g. stigma and discrimination, gender-based violence, anxiety, depression); identify biomedical, structural, and psychosocial factors impacting physical and mental health among transgender people; describe the structural barriers to healthcare experienced by transgender people as well as develop the guidance on holistic healthcare policies for transgender people.

Conditions

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HIV STIs HCV

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

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- 150 HIV-positive participants, both who were diagnosed with HIV infection and new cases.

Newly diagnosed HIV-infected participants will be linked to care to start ART. Known HIV-positive participants will be linked to care if they are not in care already. All HIV-positive participants will undergo viral load and CD4 testing at screening/baseline, and be invited back every 6 months for assessment of adherence, viral load testing, STI testing, FBS and lipid profile. A CD4 count will be repeated at Month 12 and Month 24.

No interventions assigned to this group

- 150 HIV-negative participants who are already receiving PrEP or who will accept PrEP.

HIV-negative participants will be offered PrEP. Those who accept PrEP will enroll in the PrEP program in each country, undergo creatinine testing at screening/baseline and be invited back at Month 1, Month 3, and every three months thereafter for HIV testing and assessment of adherence. STI testing, FBS, creatinine and lipid profile will be repeated every 6 months.

No interventions assigned to this group

- 150 HIV-negative participants who will refuse PrEP.

HIV-negative participants who do not wish to start PrEP will be invited back at every three months for HIV-testing. STI-testing, FBS and lipid profile will be repeated every 6 months.

No interventions assigned to this group

Eligibility Criteria

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Inclusion Criteria

* Thai/Vietnamese/Filipino nationality
* Aged ≥ 18 years old
* Self-identify as a transgender woman or transgender man
* Have signed consent form

Exclusion Criteria

* None
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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amfAR, The Foundation for AIDS Research

OTHER

Sponsor Role collaborator

Institute of HIV Research and Innovation Foundation, Thailand

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Locations

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Victoria by LoveYourself

Pasay, Manila, Philippines

Site Status RECRUITING

Rainbow Sky Association of Thailand (RSAT)

Bangkok, Bangkapi, Thailand

Site Status RECRUITING

Institute of HIV Research and Innovation

Pathum Wan, Bangkok, Thailand

Site Status RECRUITING

Tangerine Clinic, Institute of HIV Research and Innovation

Pathum Wan, Bangkok, Thailand

Site Status RECRUITING

Glink Clinics, Ho Chi Minh City (HCMC), Vietnam Glink Clinic HCMC1

Ho Chi Minh City, Thuong Kiet Street, Vietnam

Site Status RECRUITING

Countries

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Philippines Thailand Vietnam

Central Contacts

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Nittaya Phanuphak, MD,PhD.

Role: CONTACT

6681 825 3544

Rena Janamnuaysook, MBA

Role: CONTACT

6698 516 4562

Facility Contacts

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Ronivin Pagtakhan, PhD Ed

Role: primary

639778152444

Tanachai Chaisalee

Role: primary

6683 897 1691

Phubet Panpet

Role: backup

6663 217 1069

Nittaya Phanuphak, MD.,Ph.D.

Role: primary

+66 2 1605371

Rena Janamnuaysook, MBA

Role: backup

+66 2 1605371

Nittaya Phanuphak, MD.,Ph.D.

Role: primary

+66 2 1605371

Rena Janamnuaysook, MBA

Role: backup

+66 2 1605371

Thanh Le

Role: primary

0084903991705

Other Identifiers

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IHRI017

Identifier Type: -

Identifier Source: org_study_id

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