Post-acute Care for Patients With Frailty

NCT ID: NCT05452395

Last Updated: 2022-07-11

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

254 participants

Study Classification

INTERVENTIONAL

Study Start Date

2020-06-19

Study Completion Date

2020-12-31

Brief Summary

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Acute illness could be enormous stress for frail people. Combining comprehensive geriatric assessment and multifactorial intervention has positive effects on frail community older adults. However, few studies investigated the effects of post-acute care (PAC) in frail older patients who just recovered from acute hospitalization. This study aimed to evaluate the effects of PAC on frail older adults in Taiwan.

Detailed Description

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Frail patients aged \>= 75 were recruited and divided into PAC or control groups. The PAC group received comprehensive geriatric assessment (CGA) and multifactorial intervention for two to four weeks. The control group received CGA only. The primary outcomes were 90-day emergency room visits, readmissions, and mortality after PAC.

Conditions

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Frailty Retrospective Study

Study Design

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Allocation Method

NON_RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Study Groups

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Post-acute care

comprehensive geriatric assessment, and either home-based or hospital-based post-acute care

Group Type EXPERIMENTAL

Post-acute care

Intervention Type OTHER

A personalized care program, focusing on managing geriatric syndromes and improving functional performances.

Strength training, activities of daily living (ADL) and instrumental activities of daily living (IADL) practice, basic mobility training, reconditioning exercise, and home environment assessment and modification.

control group

comprehensive geriatric assessment only

Group Type NO_INTERVENTION

No interventions assigned to this group

Interventions

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Post-acute care

A personalized care program, focusing on managing geriatric syndromes and improving functional performances.

Strength training, activities of daily living (ADL) and instrumental activities of daily living (IADL) practice, basic mobility training, reconditioning exercise, and home environment assessment and modification.

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

1. Mild to severe frailty identified by the Clinical Frailty Scale
2. Age ≥ 75 years
3. Diagnosis with Parkinson's disease, dementia, chronic obstructive pulmonary disease, or chronic kidney disease stage three or worse
4. Acute hospital stays between 3 to 30 days with deconditioning
5. Stable medical condition with no need of intensive care, laboratory examination, or oxygen dependence

Exclusion Criteria

1. Refused to participate in the program
2. Candidate for other post-acute care programs (i.e. stroke, traumatic neurological injury, or fracture)
3. Unable to cooperate with the program due to mental or cognitive impairment
4. Long-term ventilator-dependence
5. Long-term bed-ridden status (\> 6 months)
6. Diagnosed as end of life and in need of palliative care
7. Diagnosed as major illness (i.e. end-stage renal disease) and in need of frequent inpatient treatment ( \> 3 times over recent 6 months)
8. Institutional residents
9. Home medical care participants
Minimum Eligible Age

75 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Taipei City Hospital

OTHER_GOV

Sponsor Role lead

Responsible Party

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Tai-Yin Wu

Doctor

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Tai-Yin Wu, PhD

Role: PRINCIPAL_INVESTIGATOR

Department of Family Medicine, Taipei City Hospital, Zhongxing Branch

Locations

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Taipei City Hospital

Taipei, , Taiwan

Site Status

Countries

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Taiwan

References

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Lee MC, Wu TY, Huang SJ, Chen YM, Hsiao SH, Tsai CY. Post-acute care for frail older people decreases 90-day emergency room visits, readmissions and mortality: An interventional study. PLoS One. 2023 Jan 6;18(1):e0279654. doi: 10.1371/journal.pone.0279654. eCollection 2023.

Reference Type DERIVED
PMID: 36607971 (View on PubMed)

Other Identifiers

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TPECH-frailty

Identifier Type: -

Identifier Source: org_study_id

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