Coexistence HBsAg/HBcAC, Clinical Characterístics & Outcomes

NCT ID: NCT05446532

Last Updated: 2025-05-31

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

120 participants

Study Classification

OBSERVATIONAL

Study Start Date

2022-06-15

Study Completion Date

2022-12-31

Brief Summary

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HBV infection is a dynamic process with complex interactions between virus replication and the host's immune response. The appearance of anti-HBs after HBV infection generally indicates recovery and immunity to HBV1 infection. However, there are several published studies that describe the coexistence of the marker of chronic infection (HBsAg +) and the marker of functional cure (HBsAc +). There are contradictory studies on whether the coexistence of HBsAg/HBsAc implies a different clinical course.

Detailed Description

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Conditions

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Hepatitis B

Study Design

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Observational Model Type

COHORT

Study Time Perspective

RETROSPECTIVE

Study Groups

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Not apply

None. Just registration epidemiology dates

No interventions assigned to this group

Eligibility Criteria

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Inclusion Criteria

* all those patients who have been seen in outpatient hepatology consultations and who present positive HBsAg and HBsAc serology simultaneously.

Exclusion Criteria

* Hepatitis C or HIV Co-infection
Minimum Eligible Age

18 Years

Maximum Eligible Age

90 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Hospital Mutua de Terrassa

OTHER

Sponsor Role collaborator

Consorci Sanitari de Terrassa

OTHER

Sponsor Role collaborator

Hospital Universitario La Fe

OTHER

Sponsor Role collaborator

Germans Trias i Pujol Hospital

OTHER

Sponsor Role collaborator

Corporacion Parc Tauli

OTHER

Sponsor Role lead

Responsible Party

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Mireia Miquel-Planas

Principal Investigator

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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H. Consorci Sanitari Parc Tauli

Sabadell, Barcelona, Spain

Site Status

Countries

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Spain

Other Identifiers

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2022/5032

Identifier Type: -

Identifier Source: org_study_id

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