Trial Outcomes & Findings for Role of Peanuts in Healthy Weight Gain in Athletic Individuals (NCT NCT05426109)
NCT ID: NCT05426109
Last Updated: 2025-06-10
Results Overview
Participants will be weighed on a digital scale wearing standardized lab clothes at all scheduled testing sessions throughout the study.
Recruitment status
COMPLETED
Study phase
NA
Target enrollment
33 participants
Primary outcome timeframe
1-min laboratory measurement assessed at the baseline, 3-wk, 7-wk, and 11-week test sessions.
Results posted on
2025-06-10
Participant Flow
Participant milestones
| Measure |
Peanut Snacks
Participants will be provided and consume an extra 500 kcal/day of peanut-containing snacks for 10 weeks.
Peanut snacks: Participants will undergo a 10-week diet and weight training regimen to promote healthy weight gain. These participants will receive seven 500 kcal peanut-containing (whole peanuts or peanut butter) snacks each week and consume one snack per day throughout the study. They will also perform a series of weight training exercises supervised by a personal trainer on 3 days per week.
|
No Peanut-containing Snacks
Participants will be provided and consume an extra 500 kcal/day of snacks without peanuts or peanut-containing foods for 10 weeks.
No peanut-containing snacks: Participants will undergo a 10-week diet and weight training regimen to promote healthy weight gain. These participants will receive seven 500 kcal non-peanut-containing high carbohydrate snacks each week and consume one snack per day throughout the study. They will also perform a series of weight training exercises supervised by a personal trainer on 3 days per week.
|
|---|---|---|
|
Overall Study
STARTED
|
16
|
17
|
|
Overall Study
COMPLETED
|
16
|
16
|
|
Overall Study
NOT COMPLETED
|
0
|
1
|
Reasons for withdrawal
| Measure |
Peanut Snacks
Participants will be provided and consume an extra 500 kcal/day of peanut-containing snacks for 10 weeks.
Peanut snacks: Participants will undergo a 10-week diet and weight training regimen to promote healthy weight gain. These participants will receive seven 500 kcal peanut-containing (whole peanuts or peanut butter) snacks each week and consume one snack per day throughout the study. They will also perform a series of weight training exercises supervised by a personal trainer on 3 days per week.
|
No Peanut-containing Snacks
Participants will be provided and consume an extra 500 kcal/day of snacks without peanuts or peanut-containing foods for 10 weeks.
No peanut-containing snacks: Participants will undergo a 10-week diet and weight training regimen to promote healthy weight gain. These participants will receive seven 500 kcal non-peanut-containing high carbohydrate snacks each week and consume one snack per day throughout the study. They will also perform a series of weight training exercises supervised by a personal trainer on 3 days per week.
|
|---|---|---|
|
Overall Study
Withdrawal by Subject
|
0
|
1
|
Baseline Characteristics
Only included participants who completed the 10 wk intervention
Baseline characteristics by cohort
| Measure |
Peanut Snacks
n=16 Participants
Participants will be provided and consume an extra 500 kcal/day of peanut-containing snacks for 10 weeks.
Peanut snacks: Participants will undergo a 10-week diet and weight training regimen to promote healthy weight gain. These participants will receive seven 500 kcal peanut-containing (whole peanuts or peanut butter) snacks each week and consume one snack per day throughout the study. They will also perform a series of weight training exercises supervised by a personal trainer on 3 days per week.
|
No Peanut-containing Snacks
n=16 Participants
Participants will be provided and consume an extra 500 kcal/day of snacks without peanuts or peanut-containing foods for 10 weeks.
No peanut-containing snacks: Participants will undergo a 10-week diet and weight training regimen to promote healthy weight gain. These participants will receive seven 500 kcal non-peanut-containing high carbohydrate snacks each week and consume one snack per day throughout the study. They will also perform a series of weight training exercises supervised by a personal trainer on 3 days per week.
|
Total
n=32 Participants
Total of all reporting groups
|
|---|---|---|---|
|
Age, Continuous
|
23 years
n=5 Participants • Only included participants who completed the 10 wk intervention
|
22 years
n=7 Participants • Only included participants who completed the 10 wk intervention
|
23 years
n=5 Participants • Only included participants who completed the 10 wk intervention
|
|
Sex: Female, Male
Female
|
6 Participants
n=5 Participants • Only including participants who completed the 10 week intervention
|
7 Participants
n=7 Participants • Only including participants who completed the 10 week intervention
|
13 Participants
n=5 Participants • Only including participants who completed the 10 week intervention
|
|
Sex: Female, Male
Male
|
10 Participants
n=5 Participants • Only including participants who completed the 10 week intervention
|
9 Participants
n=7 Participants • Only including participants who completed the 10 week intervention
|
19 Participants
n=5 Participants • Only including participants who completed the 10 week intervention
|
|
Race/Ethnicity, Customized
Reported Race · Asian
|
1 Participants
n=5 Participants
|
0 Participants
n=7 Participants
|
1 Participants
n=5 Participants
|
|
Race/Ethnicity, Customized
Reported Race · White
|
12 Participants
n=5 Participants
|
12 Participants
n=7 Participants
|
24 Participants
n=5 Participants
|
|
Race/Ethnicity, Customized
Reported Race · Black/African American
|
1 Participants
n=5 Participants
|
0 Participants
n=7 Participants
|
1 Participants
n=5 Participants
|
|
Race/Ethnicity, Customized
Reported Race · Hispanic/Latino
|
2 Participants
n=5 Participants
|
2 Participants
n=7 Participants
|
4 Participants
n=5 Participants
|
|
Race/Ethnicity, Customized
Reported Race · Mixed (≥2 race categories)
|
0 Participants
n=5 Participants
|
2 Participants
n=7 Participants
|
2 Participants
n=5 Participants
|
|
Total Body Mass
|
67.7 kg
STANDARD_DEVIATION 12.7 • n=5 Participants • Only including participants who completed the 10-week intervention
|
70.4 kg
STANDARD_DEVIATION 10.1 • n=7 Participants • Only including participants who completed the 10-week intervention
|
69 kg
STANDARD_DEVIATION 11.4 • n=5 Participants • Only including participants who completed the 10-week intervention
|
PRIMARY outcome
Timeframe: 1-min laboratory measurement assessed at the baseline, 3-wk, 7-wk, and 11-week test sessions.Participants will be weighed on a digital scale wearing standardized lab clothes at all scheduled testing sessions throughout the study.
Outcome measures
| Measure |
Peanut Snacks
n=16 Participants
Participants will be provided and consume an extra 500 kcal/day of peanut-containing snacks for 10 weeks.
Peanut snacks: Participants will undergo a 10-week diet and weight training regimen to promote healthy weight gain. These participants will receive seven 500 kcal peanut-containing (whole peanuts or peanut butter) snacks each week and consume one snack per day throughout the study. They will also perform a series of weight training exercises supervised by a personal trainer on 3 days per week.
|
No Peanut-containing Snacks
n=16 Participants
Participants will be provided and consume an extra 500 kcal/day of snacks without peanuts or peanut-containing foods for 10 weeks.
No peanut-containing snacks: Participants will undergo a 10-week diet and weight training regimen to promote healthy weight gain. These participants will receive seven 500 kcal non-peanut-containing high carbohydrate snacks each week and consume one snack per day throughout the study. They will also perform a series of weight training exercises supervised by a personal trainer on 3 days per week.
|
|---|---|---|
|
Change in Total Body Mass (Weight)
3-wk
|
0.8 kg
Standard Deviation 0.4
|
1.2 kg
Standard Deviation 0.3
|
|
Change in Total Body Mass (Weight)
11-wk
|
1.6 kg
Standard Deviation 1.1
|
2.7 kg
Standard Deviation 1.2
|
|
Change in Total Body Mass (Weight)
7-wk
|
1.8 kg
Standard Deviation 0.2
|
2.2 kg
Standard Deviation 0.1
|
PRIMARY outcome
Timeframe: 10-min laboratory measurement assessed at the baseline, 3-wk, 7-wk and 11-week test sessions.Participants will undergo a dual-energy x-ray absorptiometry scan wearing standardized lab clothing at all scheduled testing sessions throughout the study. The scan analysis provides body composition results, including lean (fat-free) mass (kg).
Outcome measures
| Measure |
Peanut Snacks
n=16 Participants
Participants will be provided and consume an extra 500 kcal/day of peanut-containing snacks for 10 weeks.
Peanut snacks: Participants will undergo a 10-week diet and weight training regimen to promote healthy weight gain. These participants will receive seven 500 kcal peanut-containing (whole peanuts or peanut butter) snacks each week and consume one snack per day throughout the study. They will also perform a series of weight training exercises supervised by a personal trainer on 3 days per week.
|
No Peanut-containing Snacks
n=16 Participants
Participants will be provided and consume an extra 500 kcal/day of snacks without peanuts or peanut-containing foods for 10 weeks.
No peanut-containing snacks: Participants will undergo a 10-week diet and weight training regimen to promote healthy weight gain. These participants will receive seven 500 kcal non-peanut-containing high carbohydrate snacks each week and consume one snack per day throughout the study. They will also perform a series of weight training exercises supervised by a personal trainer on 3 days per week.
|
|---|---|---|
|
Change in Lean Body Mass
11-wk
|
1.2 kg
Standard Deviation 1.1
|
1.9 kg
Standard Deviation 1.0
|
|
Change in Lean Body Mass
7-wk
|
1.5 kg
Standard Deviation 0
|
1.7 kg
Standard Deviation 0
|
|
Change in Lean Body Mass
3-wk
|
0.8 kg
Standard Deviation 0.4
|
1.1 kg
Standard Deviation 0.3
|
SECONDARY outcome
Timeframe: 60-min laboratory measurement assessed at the baseline, 3-week, and 11-week test sessions.Participants will undergo a resting metabolic rate (RMR) test during select testing sessions throughout the study. The indirect calorimetry test measures the daily energy expenditure (or number of kilocalories needed to perform and maintain daily bodily functions) of each participant based on the measured gas exchange during the test.
Outcome measures
| Measure |
Peanut Snacks
n=16 Participants
Participants will be provided and consume an extra 500 kcal/day of peanut-containing snacks for 10 weeks.
Peanut snacks: Participants will undergo a 10-week diet and weight training regimen to promote healthy weight gain. These participants will receive seven 500 kcal peanut-containing (whole peanuts or peanut butter) snacks each week and consume one snack per day throughout the study. They will also perform a series of weight training exercises supervised by a personal trainer on 3 days per week.
|
No Peanut-containing Snacks
n=16 Participants
Participants will be provided and consume an extra 500 kcal/day of snacks without peanuts or peanut-containing foods for 10 weeks.
No peanut-containing snacks: Participants will undergo a 10-week diet and weight training regimen to promote healthy weight gain. These participants will receive seven 500 kcal non-peanut-containing high carbohydrate snacks each week and consume one snack per day throughout the study. They will also perform a series of weight training exercises supervised by a personal trainer on 3 days per week.
|
|---|---|---|
|
Change in Resting Metabolic Rate
11-wk
|
1627 kcal/day
Standard Error 369
|
1717 kcal/day
Standard Error 338
|
|
Change in Resting Metabolic Rate
3-wk
|
1595 kcal/day
Standard Error 253
|
1706 kcal/day
Standard Error 258
|
|
Change in Resting Metabolic Rate
BSL
|
1541 kcal/day
Standard Error 285
|
1632 kcal/day
Standard Error 262
|
SECONDARY outcome
Timeframe: 5-min laboratory measurement assessed at the baseline, 3-week, 7-week, and 11-week test sessions.Participants will have their blood collected by venipuncture in aseptic conditions. Testosterone (free) will be measured to determine the impact of the extra daily 500 kcal snacks on anabolism and muscle growth.
Outcome measures
| Measure |
Peanut Snacks
n=16 Participants
Participants will be provided and consume an extra 500 kcal/day of peanut-containing snacks for 10 weeks.
Peanut snacks: Participants will undergo a 10-week diet and weight training regimen to promote healthy weight gain. These participants will receive seven 500 kcal peanut-containing (whole peanuts or peanut butter) snacks each week and consume one snack per day throughout the study. They will also perform a series of weight training exercises supervised by a personal trainer on 3 days per week.
|
No Peanut-containing Snacks
n=16 Participants
Participants will be provided and consume an extra 500 kcal/day of snacks without peanuts or peanut-containing foods for 10 weeks.
No peanut-containing snacks: Participants will undergo a 10-week diet and weight training regimen to promote healthy weight gain. These participants will receive seven 500 kcal non-peanut-containing high carbohydrate snacks each week and consume one snack per day throughout the study. They will also perform a series of weight training exercises supervised by a personal trainer on 3 days per week.
|
|---|---|---|
|
Change in Testosterone Levels
11-wk
|
18.5 pg/mL
Standard Deviation 10.7
|
20.0 pg/mL
Standard Deviation 10.3
|
|
Change in Testosterone Levels
7-wk
|
19.0 pg/mL
Standard Deviation 10.2
|
20.9 pg/mL
Standard Deviation 9.8
|
|
Change in Testosterone Levels
3-wk
|
18.5 pg/mL
Standard Deviation 9.5
|
21.4 pg/mL
Standard Deviation 11.3
|
|
Change in Testosterone Levels
baseline
|
21.7 pg/mL
Standard Deviation 9.7
|
23.5 pg/mL
Standard Deviation 11.9
|
SECONDARY outcome
Timeframe: 5-min laboratory measurement assessed at the baseline, 3-week, 7-week, and 11-week test sessions.Participants will have their blood collected by venipuncture in aseptic conditions. Insulin-like growth factor (IGF) will be measured to determine the impact of the extra daily 500 kcal snacks on anabolism and muscle growth.
Outcome measures
| Measure |
Peanut Snacks
n=16 Participants
Participants will be provided and consume an extra 500 kcal/day of peanut-containing snacks for 10 weeks.
Peanut snacks: Participants will undergo a 10-week diet and weight training regimen to promote healthy weight gain. These participants will receive seven 500 kcal peanut-containing (whole peanuts or peanut butter) snacks each week and consume one snack per day throughout the study. They will also perform a series of weight training exercises supervised by a personal trainer on 3 days per week.
|
No Peanut-containing Snacks
n=16 Participants
Participants will be provided and consume an extra 500 kcal/day of snacks without peanuts or peanut-containing foods for 10 weeks.
No peanut-containing snacks: Participants will undergo a 10-week diet and weight training regimen to promote healthy weight gain. These participants will receive seven 500 kcal non-peanut-containing high carbohydrate snacks each week and consume one snack per day throughout the study. They will also perform a series of weight training exercises supervised by a personal trainer on 3 days per week.
|
|---|---|---|
|
Change in Insulin-Like Growth Factor Levels
11-wk
|
51.3 ng/mL
Standard Deviation 21.4
|
53.4 ng/mL
Standard Deviation 13.7
|
|
Change in Insulin-Like Growth Factor Levels
7-wk
|
51.1 ng/mL
Standard Deviation 17.4
|
49.4 ng/mL
Standard Deviation 21.5
|
|
Change in Insulin-Like Growth Factor Levels
3-wk
|
47.9 ng/mL
Standard Deviation 20.2
|
45.0 ng/mL
Standard Deviation 16.4
|
|
Change in Insulin-Like Growth Factor Levels
baseline
|
49.8 ng/mL
Standard Deviation 16.4
|
49.6 ng/mL
Standard Deviation 14.2
|
Adverse Events
Peanut Snacks
Serious events: 0 serious events
Other events: 0 other events
Deaths: 0 deaths
No Peanut-containing Snacks
Serious events: 0 serious events
Other events: 0 other events
Deaths: 0 deaths
Serious adverse events
Adverse event data not reported
Other adverse events
Adverse event data not reported
Additional Information
Results disclosure agreements
- Principal investigator is a sponsor employee
- Publication restrictions are in place