A Pharmacy-based Observational Study to Learn More About Iberogast Advance in the Real-world Setting

NCT ID: NCT05389709

Last Updated: 2023-12-26

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

184 participants

Study Classification

OBSERVATIONAL

Study Start Date

2022-06-04

Study Completion Date

2023-05-11

Brief Summary

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This is an observational study in which data from people with functional gastrointestinal disorders who decide on their own or by recommendation of their doctors or pharmacists to take Iberogast Advance are collected and studied. In observational studies, only observations are made without specified advice or interventions.

Functional stomach and bowel (or gastrointestinal) disorders are conditions in which the functionality of the gut, mainly the gut muscles or the gut/brain axis, is disturbed. Functional stomach and bowel disorders cause symptoms like heartburn, cramps and pain of the upper and middle part of the belly, also known as functional dyspepsia (FD) and irritable bowel syndrome (IBS). IBS affects predominantly the lower digestive system and causes symptoms like pain of the belly, cramps, bloating, diarrhea, and constipation.

Iberogast Advance is already available in German pharmacies without prescription for patients with gastrointestinal disorders such as FD and IBS. It contains herb extracts that work against inflammation, are calming, and protect the mucosa (innermost layer of the gastrointestinal tract). Earlier controlled studies with Iberogast Advance have shown how well it works and how it affects the body. Since Iberogast Advance is only available since October 2020, there is no information on its use in the real-world setting yet.

Therefore, the study researchers want to collect data on the use of Iberogast Advance in the real-world setting.

To do this, people with long-term and repeated functional gastrointestinal symptoms who purchase Iberogast Advance from participating pharmacies across Germany will be asked to fill out a questionnaire optionally covering 6 weeks of treatment. The participants will take Iberogast Advance as recommended in the product information.

The main purpose of this study is to see how well Iberogast Advance works and is perceived in the real-world setting. Participants will record how they experience a change of their gastrointestinal symptoms (assessed single-symptom-based) from start and during 6 weeks of treatment. Researchers will then compare the differences and analyze treatment effects.

The researchers will additionally collect information on usage behavior, characteristics of the patients, their symptoms, tolerability and their satisfaction with Iberogast Advance.

There will be no required tests or visits with a study doctor in this study. The researchers will collect the results of the patient questionnaires from Jun 2022 to January 2023.

Detailed Description

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Conditions

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Functional Gastrointestinal Disorders Such as Irritable Bowel Syndrome and Functional Dyspepsia Irritable Bowel Syndrome Functional Dyspepsia

Keywords

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Iberogast Advance

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

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Pharmacy based survey

Patients receive a questionnaire to fill out and return it the Contract Research Organization (CRO) or, alternatively to the pharmacy.

Iberogast (STW5-II, BAY98-7410)

Intervention Type DRUG

Survey without any intervention assigned in the study.

Interventions

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Iberogast (STW5-II, BAY98-7410)

Survey without any intervention assigned in the study.

Intervention Type DRUG

Other Intervention Names

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Iberogast® Advance

Eligibility Criteria

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Inclusion Criteria

* Adult female or male subject aged ≥ 18
* Decision to initiate treatment with Iberogast Advance was made as per pharmacist's routine recommendation practice/by the subject
* Subject purchases Iberogast Advance for his own use
* Not pregnant or lactating
* Not hypersensitive to any of the ingredients of Iberogast Advance

Exclusion Criteria

* Patients with known hypersensitivity to any of the ingredients of Iberogast Advance
* Pregnant or lactating women
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Bayer

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Locations

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Many Locations

Multiple Locations, Many Locations, Germany

Site Status

Countries

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Germany

Related Links

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https://clinicaltrials.bayer.com/

Click here for access to information about Bayer's transparency standards and Bayer studies.

Other Identifiers

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21970

Identifier Type: -

Identifier Source: org_study_id