Risk Assessment Tool for Graft Survival in Pediatric Kidney Transplantation

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.

Recruitment Status

COMPLETED

Total Enrollment

1425 participants

Study Classification

OBSERVATIONAL

Study Start Date

1966-01-31

Study Completion Date

2022-01-01

Brief Summary

Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.

Registry study in which data of all pediatric kidney recipients in the Netherlands (registered in the Nederlandse Orgaan Transplantatie Registry) are studied to develop a risk calculator for graft loss.

Detailed Description

Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.

The pre-transplantation parameters of all recipients are used to do a multivariable regression analysis.

The B-coefficients of this analysis will be used to develop a risk calculator that predicts graft survival after transplantation per year of transplantation.

Conditions

See the medical conditions and disease areas that this research is targeting or investigating.

Kidney Transplant Failure and Rejection Pediatric Kidney Disease

Study Design

Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.

Observational Model Type

COHORT

Study Time Perspective

RETROSPECTIVE

Interventions

Learn about the drugs, procedures, or behavioral strategies being tested and how they are applied within this trial.

None, transplantation recipients

None, observational

Intervention Type OTHER

Eligibility Criteria

Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.

Inclusion Criteria

Pediatric kidney recipients

* transplantation in the Netherlands
* signed informed consent

Exclusion Criteria

* combined transplantation (pancreas-kidney of liver-kidney transplantation)
* No informed consent

Minimum Eligible Age

0 Years

Maximum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Responsible Party

Identify the individual or organization who holds primary responsibility for the study information submitted to regulators.

Responsibility Role SPONSOR

Principal Investigators

Learn about the lead researchers overseeing the trial and their institutional affiliations.

Liesbeth De Wall

Role: PRINCIPAL_INVESTIGATOR

Radboud University Medical Center

References

Explore related publications, articles, or registry entries linked to this study.

Oomen L, de Jong H, Bouts AHM, Keijzer-Veen MG, Cornelissen EAM, de Wall LL, Feitz WFJ, Bootsma-Robroeks CMHHT. A pre-transplantation risk assessment tool for graft survival in Dutch pediatric kidney recipients. Clin Kidney J. 2023 Mar 23;16(7):1122-1131. doi: 10.1093/ckj/sfad057. eCollection 2023 Jul.

Reference Type DERIVED

PMID: 37398686 (View on PubMed)

Other Identifiers

Review additional registry numbers or institutional identifiers associated with this trial.

Riskcalculator.Pediatric.ntx

Identifier Type: -

Identifier Source: org_study_id