Trial Outcomes & Findings for Study To Assess Radiofrequency Diathermocontraction Device For Muscle Stimulation And The Treatment Of Abdominal Fat (NCT NCT05388617)

NCT ID: NCT05388617

Last Updated: 2023-11-29

Results Overview

The number of subjects satisfied with their treatment will be reported.

Recruitment status

TERMINATED

Study phase

NA

Target enrollment

16 participants

Primary outcome timeframe

30 days follow up.

Results posted on

2023-11-29

Participant Flow

Participant milestones

Participant milestones
Measure
Group A
Subjects in Group A will receive up to 8 treatments with the Brera/Med 400 device on their abdomen or flanks. Subjects may receive a phone call 1 week (1-7 days) after each treatment to record side effects. Subjects will return for follow up visits at 30 and 90 days post last treatment for efficacy and side effects assessments. Brera: The applicators will be placed in contact with the skin. The entire defined treatment area will then be treated by delivering energy to the skin. Temperature may be continuously monitored and recorded during treatment. Parameters may be adjusted throughout the treatment to increase subject comfort.
Group B
Subjects in Group B may receive up to 8 treatments with the Brera/Med 400 device on their abdomen and/or flanks. Subjects may receive a phone call 1 week (1-7 days) after each treatment to record side effects. Subjects may be asked return for follow up visits at 30 and 90 days post last treatment for efficacy and side effects assessments. Outcome measures will not be taken for subjects enrolled in this group. Brera: The applicators will be placed in contact with the skin. The entire defined treatment area will then be treated by delivering energy to the skin. Temperature may be continuously monitored and recorded during treatment. Parameters may be adjusted throughout the treatment to increase subject comfort.
Overall Study
STARTED
16
0
Overall Study
COMPLETED
16
0
Overall Study
NOT COMPLETED
0
0

Reasons for withdrawal

Withdrawal data not reported

Baseline Characteristics

Study To Assess Radiofrequency Diathermocontraction Device For Muscle Stimulation And The Treatment Of Abdominal Fat

Baseline characteristics by cohort

Baseline characteristics by cohort
Measure
Group A
n=16 Participants
Subjects in Group A will receive up to 8 treatments with the Brera/Med 400 device on their abdomen or flanks. Subjects may receive a phone call 1 week (1-7 days) after each treatment to record side effects. Subjects will return for follow up visits at 30 and 90 days post last treatment for efficacy and side effects assessments. Brera: The applicators will be placed in contact with the skin. The entire defined treatment area will then be treated by delivering energy to the skin. Temperature may be continuously monitored and recorded during treatment. Parameters may be adjusted throughout the treatment to increase subject comfort.
Group B
Subjects in Group B may receive up to 8 treatments with the Brera/Med 400 device on their abdomen and/or flanks. Subjects may receive a phone call 1 week (1-7 days) after each treatment to record side effects. Subjects may be asked return for follow up visits at 30 and 90 days post last treatment for efficacy and side effects assessments. Outcome measures will not be taken for subjects enrolled in this group. Brera: The applicators will be placed in contact with the skin. The entire defined treatment area will then be treated by delivering energy to the skin. Temperature may be continuously monitored and recorded during treatment. Parameters may be adjusted throughout the treatment to increase subject comfort.
Total
n=16 Participants
Total of all reporting groups
Age, Categorical
<=18 years
0 Participants
n=5 Participants
0 Participants
n=7 Participants
0 Participants
n=5 Participants
Age, Categorical
Between 18 and 65 years
16 Participants
n=5 Participants
0 Participants
n=7 Participants
16 Participants
n=5 Participants
Age, Categorical
>=65 years
0 Participants
n=5 Participants
0 Participants
n=7 Participants
0 Participants
n=5 Participants
Sex: Female, Male
Female
14 Participants
n=5 Participants
0 Participants
n=7 Participants
14 Participants
n=5 Participants
Sex: Female, Male
Male
2 Participants
n=5 Participants
0 Participants
n=7 Participants
2 Participants
n=5 Participants
Race/Ethnicity, Customized
Caucasian
13 Participants
n=5 Participants
0 Participants
n=7 Participants
13 Participants
n=5 Participants
Race/Ethnicity, Customized
Hispanic
1 Participants
n=5 Participants
0 Participants
n=7 Participants
1 Participants
n=5 Participants
Race/Ethnicity, Customized
Asian/Indian
1 Participants
n=5 Participants
0 Participants
n=7 Participants
1 Participants
n=5 Participants
Race/Ethnicity, Customized
Dominican/American
1 Participants
n=5 Participants
0 Participants
n=7 Participants
1 Participants
n=5 Participants
FitzPatrick Skin Type
Fitzpatrick Skin Type I
0 Participants
n=5 Participants
0 Participants
n=7 Participants
0 Participants
n=5 Participants
FitzPatrick Skin Type
Fitzpatrick Skin Type II
5 Participants
n=5 Participants
0 Participants
n=7 Participants
5 Participants
n=5 Participants
FitzPatrick Skin Type
Fitzpatrick Skin Type III
10 Participants
n=5 Participants
0 Participants
n=7 Participants
10 Participants
n=5 Participants
FitzPatrick Skin Type
Fitzpatrick Skin Type IV
1 Participants
n=5 Participants
0 Participants
n=7 Participants
1 Participants
n=5 Participants
FitzPatrick Skin Type
Fitzpatrick Skin Type V
0 Participants
n=5 Participants
0 Participants
n=7 Participants
0 Participants
n=5 Participants
FitzPatrick Skin Type
Fitzpatrick Skin Type VI
0 Participants
n=5 Participants
0 Participants
n=7 Participants
0 Participants
n=5 Participants

PRIMARY outcome

Timeframe: 30 days follow up.

Population: There were no subjects enrolled for Group B.

The number of subjects satisfied with their treatment will be reported.

Outcome measures

Outcome measures
Measure
Group A
n=16 Participants
Subjects in Group A will receive up to 8 treatments with the Brera/Med 400 device on their abdomen or flanks. Subjects may receive a phone call 1 week (1-7 days) after each treatment to record side effects. Subjects will return for follow up visits at 30 and 90 days post last treatment for efficacy and side effects assessments. Brera: The applicators will be placed in contact with the skin. The entire defined treatment area will then be treated by delivering energy to the skin. Temperature may be continuously monitored and recorded during treatment. Parameters may be adjusted throughout the treatment to increase subject comfort.
Group B
Subjects in Group B may receive up to 8 treatments with the Brera/Med 400 device on their abdomen and/or flanks. Subjects may receive a phone call 1 week (1-7 days) after each treatment to record side effects. Subjects may be asked return for follow up visits at 30 and 90 days post last treatment for efficacy and side effects assessments. Outcome measures will not be taken for subjects enrolled in this group. Brera: The applicators will be placed in contact with the skin. The entire defined treatment area will then be treated by delivering energy to the skin. Temperature may be continuously monitored and recorded during treatment. Parameters may be adjusted throughout the treatment to increase subject comfort.
Number of Subjects Satisfied
10 number of participants satisfied

Adverse Events

Group A

Serious events: 0 serious events
Other events: 13 other events
Deaths: 0 deaths

Group B

Serious events: 0 serious events
Other events: 0 other events
Deaths: 0 deaths

Serious adverse events

Adverse event data not reported

Other adverse events

Other adverse events
Measure
Group A
n=16 participants at risk
Subjects in Group A will receive up to 8 treatments with the Brera/Med 400 device on their abdomen or flanks. Subjects may receive a phone call 1 week (1-7 days) after each treatment to record side effects. Subjects will return for follow up visits at 30 and 90 days post last treatment for efficacy and side effects assessments. Brera: The applicators will be placed in contact with the skin. The entire defined treatment area will then be treated by delivering energy to the skin. Temperature may be continuously monitored and recorded during treatment. Parameters may be adjusted throughout the treatment to increase subject comfort.
Group B
Subjects in Group B may receive up to 8 treatments with the Brera/Med 400 device on their abdomen and/or flanks. Subjects may receive a phone call 1 week (1-7 days) after each treatment to record side effects. Subjects may be asked return for follow up visits at 30 and 90 days post last treatment for efficacy and side effects assessments. Outcome measures will not be taken for subjects enrolled in this group. Brera: The applicators will be placed in contact with the skin. The entire defined treatment area will then be treated by delivering energy to the skin. Temperature may be continuously monitored and recorded during treatment. Parameters may be adjusted throughout the treatment to increase subject comfort.
Skin and subcutaneous tissue disorders
Erythema
18.8%
3/16 • Adverse events were captured throughout subject participation in the study, approximately 30 days.
13 out of the 16 subjects who received treatments in Group A observed adverse events.
0/0 • Adverse events were captured throughout subject participation in the study, approximately 30 days.
13 out of the 16 subjects who received treatments in Group A observed adverse events.
Skin and subcutaneous tissue disorders
Cramping
37.5%
6/16 • Adverse events were captured throughout subject participation in the study, approximately 30 days.
13 out of the 16 subjects who received treatments in Group A observed adverse events.
0/0 • Adverse events were captured throughout subject participation in the study, approximately 30 days.
13 out of the 16 subjects who received treatments in Group A observed adverse events.
Skin and subcutaneous tissue disorders
Muscle Twitching
6.2%
1/16 • Adverse events were captured throughout subject participation in the study, approximately 30 days.
13 out of the 16 subjects who received treatments in Group A observed adverse events.
0/0 • Adverse events were captured throughout subject participation in the study, approximately 30 days.
13 out of the 16 subjects who received treatments in Group A observed adverse events.
Skin and subcutaneous tissue disorders
Pain/Tenderness
50.0%
8/16 • Adverse events were captured throughout subject participation in the study, approximately 30 days.
13 out of the 16 subjects who received treatments in Group A observed adverse events.
0/0 • Adverse events were captured throughout subject participation in the study, approximately 30 days.
13 out of the 16 subjects who received treatments in Group A observed adverse events.

Additional Information

Jamie Trimper

Cynosure

Phone: 9782564200

Results disclosure agreements

  • Principal investigator is a sponsor employee The PI cannot disclose confidential or proprietary information until after it becomes generally known or available to the public.
  • Publication restrictions are in place

Restriction type: OTHER