Cannabis Tolerance Break Resource Study: T-Break Guide

NCT ID: NCT05382273

Last Updated: 2022-05-19

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

151 participants

Study Classification

OBSERVATIONAL

Study Start Date

2021-04-22

Study Completion Date

2021-08-01

Brief Summary

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The purpose of this pilot study is to conduct research into the value of using the T-Break Guide for assisting people taking a tolerance break from cannabis. The hope is that this initial research will yield some insights and benchmarks into the Guide's efficacy, and provide a foundation for a later randomized control study.

The following are some key research questions:

1. How did participants use the Guide? (Eg: daily; read once; 'a la carte')
2. How did using the Guide increase fidelity to tolerance break (starting, continuing, completing a break)?
3. Did using the Guide yield any benefits beyond tolerance break fidelity? (Eg: insight into patterns of use)

Detailed Description

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The pilot study used a pretest-posttest design in which participants completed a baseline survey and were asked to attempt a 21-day period of cannabis abstinence, to consider using the T-Break Guide (intervention) in their attempt, and to complete a follow-up survey after 30 days.

Participants were young adults aged 18-29 recruited through posters and tabling events at the University of Vermont (UVM), a post on a UVM webpage, emails on listservs of seven other universities, and a post on a subreddit focusing on responsible cannabis use. The posters and online announcements directed participants to the online baseline survey, which contained consent information before allowing participants to complete.

After completing the baseline survey, participants received a link to an online version of the T-Break Guide through email. After 30 days, participants received another email prompting them to complete the follow-up survey. The UVM Institutional Review Board reviewed and approved all study procedures (STUDY00001489).

Conditions

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Cannabis Use Tolerance Cannabis Withdrawal

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

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Use of T-Break Guide: None

Participants who reported not using the T-Break Guide (intervention)

No interventions assigned to this group

Use of T-Break Guide: Some

Participants who reported using the T-Break Guide "some"

T-Break Guide

Intervention Type BEHAVIORAL

The T-Break Guide was designed to help people complete a 21-day break from cannabis. For each day of the break, the Guide offers inspiration in the form of a quote, reflections based on likely experiences occurring at that point during the break, advice on ways to overcome challenges, alternative activities in which to engage, and encouragement.

* The first week focuses on physical symptoms of cannabis withdrawal (e.g., sleep, appetite).
* The second week focuses on the emotional experience (e.g., anxiety, boredom).
* The third week focuses on behavioral aspects (e.g., examining patterns, connections).

The T-Break Guide follows the Motivational Interviewing principles of affirmation and autonomy.

Use of T-Break Guide: A lot

Participants who reported using the T-Break Guide "a lot"

T-Break Guide

Intervention Type BEHAVIORAL

The T-Break Guide was designed to help people complete a 21-day break from cannabis. For each day of the break, the Guide offers inspiration in the form of a quote, reflections based on likely experiences occurring at that point during the break, advice on ways to overcome challenges, alternative activities in which to engage, and encouragement.

* The first week focuses on physical symptoms of cannabis withdrawal (e.g., sleep, appetite).
* The second week focuses on the emotional experience (e.g., anxiety, boredom).
* The third week focuses on behavioral aspects (e.g., examining patterns, connections).

The T-Break Guide follows the Motivational Interviewing principles of affirmation and autonomy.

Interventions

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T-Break Guide

The T-Break Guide was designed to help people complete a 21-day break from cannabis. For each day of the break, the Guide offers inspiration in the form of a quote, reflections based on likely experiences occurring at that point during the break, advice on ways to overcome challenges, alternative activities in which to engage, and encouragement.

* The first week focuses on physical symptoms of cannabis withdrawal (e.g., sleep, appetite).
* The second week focuses on the emotional experience (e.g., anxiety, boredom).
* The third week focuses on behavioral aspects (e.g., examining patterns, connections).

The T-Break Guide follows the Motivational Interviewing principles of affirmation and autonomy.

Intervention Type BEHAVIORAL

Eligibility Criteria

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Inclusion Criteria

* Current cannabis partakers, willing to attempt at 21 day tolerance break (ie, period of cannabis abstinence)

Exclusion Criteria

* No cannabis use in past month
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Dartmouth College

OTHER

Sponsor Role collaborator

Rutgers University

OTHER

Sponsor Role collaborator

University of Vermont

OTHER

Sponsor Role lead

Responsible Party

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Tom Fontana

Alcohol, Cannabis & Other Drugs Initiatives Manager

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Tom Fontana, MS

Role: PRINCIPAL_INVESTIGATOR

University of Vermont

Locations

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University of Vermont

Burlington, Vermont, United States

Site Status

Countries

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United States

References

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Enkema MC, Hallgren KA, Larimer ME. Craving is impermanent and it matters: Investigating craving and cannabis use among young adults with problematic use interested in reducing use. Drug Alcohol Depend. 2020 May 1;210:107957. doi: 10.1016/j.drugalcdep.2020.107957. Epub 2020 Mar 14.

Reference Type BACKGROUND
PMID: 32200158 (View on PubMed)

Enkema MC, Hallgren KA, Bowen S, Lee CM, Larimer ME. Craving management: Exploring factors that influence momentary craving-related risk of cannabis use among young adults. Addict Behav. 2021 Apr;115:106750. doi: 10.1016/j.addbeh.2020.106750. Epub 2020 Dec 3.

Reference Type BACKGROUND
PMID: 33383565 (View on PubMed)

Schuster RM, Gilman J, Schoenfeld D, Evenden J, Hareli M, Ulysse C, Nip E, Hanly A, Zhang H, Evins AE. One Month of Cannabis Abstinence in Adolescents and Young Adults Is Associated With Improved Memory. J Clin Psychiatry. 2018 Oct 30;79(6):17m11977. doi: 10.4088/JCP.17m11977.

Reference Type BACKGROUND
PMID: 30408351 (View on PubMed)

Other Identifiers

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03420-08153

Identifier Type: OTHER_GRANT

Identifier Source: secondary_id

STUDY00001489

Identifier Type: -

Identifier Source: org_study_id

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