The Effects of Body Mass Index on Thoracic Paravertebral Block Analgesia

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.

Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

75 participants

Study Classification

INTERVENTIONAL

Study Start Date

2022-04-25

Study Completion Date

2023-05-13

Brief Summary

Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.

Obesity has become one of the world's leading health problems. It is known that obesity causes many diseases and negatively affects the quality of life. For this reason, many conditions that are thought to be effective in obesity and concern the quality of life of patients have been scientifically researched and continue to be investigated. One of them is postoperative pain. Although there are studies stating that there is no relationship between body mass index (BMI) and postoperative pain, when the literature data is examined, it is thought that obesity is a risk factor for postoperative pain and changes pain sensitivity and analgesic needs of patients. There are also studies in the literature stating that the level of postoperative pain increases in parallel with each unit increase in BMI.

After thoracic surgery, many analgesic methods have been suggested, including thoracic epidural analgesia (TEA), thoracic paravertebral block (TPVB), intercostal nerve blocks (ICSB), erector spina plane block (ESPB), serratus anterior plane block (SAPB). This study will compare the effects of BMI on postoperative pain in patients undergoing TPVB for postoperative analgesia and thoracoscopic surgery.

Related Clinical Trials

Explore similar clinical trials based on study characteristics and research focus.

The Effects of Body Mass Index on Erector Spinae Plane Block Analgesia

NCT06257953

Pain Pain Postoperative Pain Acute +3 more

COMPLETED NA

Bilateral Thoracic Paravertebral Blocks in Obese and Non-obese Patients Undergoing Reduction Mammaplasty

NCT04596787

Pain, Postoperative Obesity Thoracic Paravertebral Blocks +2 more

COMPLETED

M-Tapa Block vs External Oblique Intercostal Block for Laparoscopic Sleeve Gastrectomy Surgery

NCT05939635

Anesthesia Regional Anesthesia Postoperative Pain

COMPLETED NA

Postoperative Analgesis for Pain Management After Thoracotomy

NCT06177652

Postoperative Pain Analgesia

COMPLETED NA

Laparoscopic Sleeve Gastrectomy Surgery and External Oblique Intercostal Block

NCT05822479

Anesthesia Regional Anesthesia Morbid Obesity +1 more

COMPLETED NA

Detailed Description

Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.

Conditions

See the medical conditions and disease areas that this research is targeting or investigating.

Pain, Postoperative Acute Pain Thoracic Paravertebral Block Body Mass Index Thoracic Surgery, Video-Assisted

Study Design

Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.

Allocation Method

NON_RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

QUADRUPLE

Participants Caregivers Investigators Outcome Assessors

Study Groups

Review each arm or cohort in the study, along with the interventions and objectives associated with them.

Patients with a BMI of 18-24.9 kg/m2

The needle will be advanced to the paravertebral area with an ultrasound-guided in-plane technique. 30 ml of 0.25% bupivacaine will be injected into this area.

Group Type ACTIVE_COMPARATOR

Thoracic Paravertebral Block

Intervention Type PROCEDURE

Thoracic paravertebral block will be applied to the patients under real-time ultrasound guidance.

Patients with a BMI of 25-29.9 kg/m2

The needle will be advanced to the paravertebral area with an ultrasound-guided in-plane technique. 30 ml of 0.25% bupivacaine will be injected into this area.

Group Type ACTIVE_COMPARATOR

Thoracic Paravertebral Block

Intervention Type PROCEDURE

Thoracic paravertebral block will be applied to the patients under real-time ultrasound guidance.

Patients with a BMI of 30-40 kg/m2

The needle will be advanced to the paravertebral area with an ultrasound-guided in-plane technique. 30 ml of 0.25% bupivacaine will be injected into this area.

Group Type ACTIVE_COMPARATOR

Thoracic Paravertebral Block

Intervention Type PROCEDURE

Thoracic paravertebral block will be applied to the patients under real-time ultrasound guidance.

Interventions

Learn about the drugs, procedures, or behavioral strategies being tested and how they are applied within this trial.

Thoracic Paravertebral Block

Thoracic paravertebral block will be applied to the patients under real-time ultrasound guidance.

Intervention Type PROCEDURE

Eligibility Criteria

Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.

Inclusion Criteria

* 18 to 80 years old
* ASA physical status I-II-III
* BMI 18 to 40 kg/m2
* Elective video-assisted thoracoscopic surgery

Exclusion Criteria

* Patient refusing the procedure
* Emergency surgery
* Chronic opioid or analgesic use
* Patients who will operate under emergency conditions
* Patients who will not undergo VATS

Minimum Eligible Age

18 Years

Maximum Eligible Age

80 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No