Trial Outcomes & Findings for Survey to Identify Substance Use in Teenagers and Adolescents (NCT NCT05353036)

NCT ID: NCT05353036

Last Updated: 2024-09-26

Results Overview

As part of standard of care, nurses contact the parents of children scheduled for surgery to obtain health history and any alcohol, drug, vaping and tobacco usage. For the study, adolescents were asked to complete a survey on REDCap regarding their alcohol, drug, vaping and tobacco usage and those responses were compared to the answers the parents gave to the nurses during pre-op phone call.

• Recruitment status: COMPLETED
• Target enrollment: 250 participants
• Primary outcome timeframe: Baseline
• Results posted on: 2024-09-26

Participant Flow

Participant milestones

Measure	Adolescents Patients 12-21 years undergoing anesthetic care Survey: REDCap survey assessing incidence, frequency, and type of illicit substance use
Overall Study STARTED	250
Overall Study COMPLETED	250
Overall Study NOT COMPLETED	0

Reasons for withdrawal

Withdrawal data not reported

Baseline Characteristics

Survey to Identify Substance Use in Teenagers and Adolescents

Baseline characteristics by cohort

Measure	Adolescents n=250 Participants Patients 12-21 years undergoing anesthetic care Survey: Survey assessing incidence, frequency, and type of illicit substance use
Age, Continuous	15.8 years STANDARD_DEVIATION 2.3 • n=5 Participants
Sex: Female, Male Female	141 Participants n=5 Participants
Sex: Female, Male Male	109 Participants n=5 Participants
Race (NIH/OMB) American Indian or Alaska Native	1 Participants n=5 Participants
Race (NIH/OMB) Asian	11 Participants n=5 Participants
Race (NIH/OMB) Native Hawaiian or Other Pacific Islander	0 Participants n=5 Participants
Race (NIH/OMB) Black or African American	37 Participants n=5 Participants
Race (NIH/OMB) White	187 Participants n=5 Participants
Race (NIH/OMB) More than one race	12 Participants n=5 Participants
Race (NIH/OMB) Unknown or Not Reported	2 Participants n=5 Participants
Region of Enrollment United States	250 participants n=5 Participants

PRIMARY outcome

Timeframe: Baseline

As part of standard of care, nurses contact the parents of children scheduled for surgery to obtain health history and any alcohol, drug, vaping and tobacco usage. For the study, adolescents were asked to complete a survey on REDCap regarding their alcohol, drug, vaping and tobacco usage and those responses were compared to the answers the parents gave to the nurses during pre-op phone call.

Outcome measures

Measure	Overall n=500 Participants Total responses from both participants and parents.	Adolescents n=250 Participants Patients 12-21 years undergoing anesthetic care Survey: Survey assessing incidence, frequency, and type of illicit substance use via REDCap	Parents n=250 Participants Parents of the adolescent participants
Number of Participants With Adolescent and Parent Reported Alcohol, Drug, Vaping and Tobacco Usage Alcohol: No response recorded	1 Participants	1 Participants	0 Participants
Number of Participants With Adolescent and Parent Reported Alcohol, Drug, Vaping and Tobacco Usage Alcohol: No	425 Participants	180 Participants	245 Participants
Number of Participants With Adolescent and Parent Reported Alcohol, Drug, Vaping and Tobacco Usage Alcohol: Yes	74 Participants	69 Participants	5 Participants
Number of Participants With Adolescent and Parent Reported Alcohol, Drug, Vaping and Tobacco Usage Drug use: No	437 Participants	198 Participants	239 Participants
Number of Participants With Adolescent and Parent Reported Alcohol, Drug, Vaping and Tobacco Usage Drug use: Yes	63 Participants	52 Participants	11 Participants
Number of Participants With Adolescent and Parent Reported Alcohol, Drug, Vaping and Tobacco Usage Vaping: No response recorded	1 Participants	1 Participants	0 Participants
Number of Participants With Adolescent and Parent Reported Alcohol, Drug, Vaping and Tobacco Usage Vaping: No	448 Participants	209 Participants	239 Participants
Number of Participants With Adolescent and Parent Reported Alcohol, Drug, Vaping and Tobacco Usage Vaping: Yes	51 Participants	40 Participants	11 Participants
Number of Participants With Adolescent and Parent Reported Alcohol, Drug, Vaping and Tobacco Usage Tobacco: No response recorded	1 Participants	1 Participants	0 Participants
Number of Participants With Adolescent and Parent Reported Alcohol, Drug, Vaping and Tobacco Usage Tobacco: No	482 Participants	237 Participants	245 Participants
Number of Participants With Adolescent and Parent Reported Alcohol, Drug, Vaping and Tobacco Usage Tobacco: Yes	17 Participants	12 Participants	5 Participants

PRIMARY outcome

Timeframe: Baseline

Adolescents were asked in a REDCap survey Do you currently or have you ever drank alcohol?

Outcome measures

Measure	Overall n=250 Participants Total responses from both participants and parents.	Adolescents Patients 12-21 years undergoing anesthetic care Survey: Survey assessing incidence, frequency, and type of illicit substance use via REDCap	Parents Parents of the adolescent participants
Alcohol Use No response recorded	1 Participants	—	—
Alcohol Use No	180 Participants	—	—
Alcohol Use Yes	69 Participants	—	—

PRIMARY outcome

Timeframe: Baseline

Adolescents were asked in a REDCap survey Do you currently or have you ever smoked or consumed marijuana, THC, or cannabis?

Outcome measures

Measure	Overall n=250 Participants Total responses from both participants and parents.	Adolescents Patients 12-21 years undergoing anesthetic care Survey: Survey assessing incidence, frequency, and type of illicit substance use via REDCap	Parents Parents of the adolescent participants
Marijuana Use No response recorded	1 Participants	—	—
Marijuana Use No	198 Participants	—	—
Marijuana Use Yes	51 Participants	—	—

PRIMARY outcome

Timeframe: Baseline

Adolescents were asked in a REDCap survey Do you currently or have you ever vaped?

Outcome measures

Measure	Overall n=250 Participants Total responses from both participants and parents.	Adolescents Patients 12-21 years undergoing anesthetic care Survey: Survey assessing incidence, frequency, and type of illicit substance use via REDCap	Parents Parents of the adolescent participants
Vape Pen Use No response recorded	1 Participants	—	—
Vape Pen Use No	209 Participants	—	—
Vape Pen Use Yes	40 Participants	—	—

PRIMARY outcome

Timeframe: Baseline

Adolescents were asked in a REDCap survey Do you currently or have you ever used tobacco?

Outcome measures

Measure	Overall n=250 Participants Total responses from both participants and parents.	Adolescents Patients 12-21 years undergoing anesthetic care Survey: Survey assessing incidence, frequency, and type of illicit substance use via REDCap	Parents Parents of the adolescent participants
Tobacco Use No response recorded	1 Participants	—	—
Tobacco Use No	237 Participants	—	—
Tobacco Use Yes	12 Participants	—	—

PRIMARY outcome

Timeframe: Baseline

Adolescents were asked in a REDCap survey Do you currently or have you ever used a prescribed opioid for acute pain?

Outcome measures

Measure	Overall n=250 Participants Total responses from both participants and parents.	Adolescents Patients 12-21 years undergoing anesthetic care Survey: Survey assessing incidence, frequency, and type of illicit substance use via REDCap	Parents Parents of the adolescent participants
Prescription Opioid Use for Acute Pain No	215 Participants	—	—
Prescription Opioid Use for Acute Pain Yes	35 Participants	—	—

SECONDARY outcome

Timeframe: Baseline

Population: The number of participants that answered yes to the currently or ever used alcohol question.

Adolescents were asked in a REDCap survey When was the last time you used alcohol?

Outcome measures

Measure	Overall n=69 Participants Total responses from both participants and parents.	Adolescents Patients 12-21 years undergoing anesthetic care Survey: Survey assessing incidence, frequency, and type of illicit substance use via REDCap	Parents Parents of the adolescent participants
Most Recent Alcohol Use Not currently using	15 Participants	—	—
Most Recent Alcohol Use Within the last 24 hours	2 Participants	—	—
Most Recent Alcohol Use Within the last week	11 Participants	—	—
Most Recent Alcohol Use Within the last year	41 Participants	—	—

SECONDARY outcome

Timeframe: Baseline

Population: The number of participants that answered yes to the currently or ever drank alcohol question.

Adolescents were asked in a REDCap survey How old were you when you first drank alcohol?

Outcome measures

Measure	Overall n=69 Participants Total responses from both participants and parents.	Adolescents Patients 12-21 years undergoing anesthetic care Survey: Survey assessing incidence, frequency, and type of illicit substance use via REDCap	Parents Parents of the adolescent participants
Age First Drank Alcohol	16 years Interval 14.0 to 17.0	—	—

SECONDARY outcome

Timeframe: Baseline

Population: The number of participants that answered yes to the currently or ever used marijuana question.

Adolescents were asked in a REDCap survey When was the last time you used marijuana?

Outcome measures

Measure	Overall n=51 Participants Total responses from both participants and parents.	Adolescents Patients 12-21 years undergoing anesthetic care Survey: Survey assessing incidence, frequency, and type of illicit substance use via REDCap	Parents Parents of the adolescent participants
Most Recent Marijuana Use Not currently using	10 Participants	—	—
Most Recent Marijuana Use Within the last 24 hours	6 Participants	—	—
Most Recent Marijuana Use Within the last week	16 Participants	—	—
Most Recent Marijuana Use Within the last year	19 Participants	—	—

SECONDARY outcome

Timeframe: Baseline

Population: The number of participants that answered yes to the currently or ever used marijuana question.

Adolescents were asked in a REDCap survey How old were you when you first started using?

Outcome measures

Measure	Overall n=51 Participants Total responses from both participants and parents.	Adolescents Patients 12-21 years undergoing anesthetic care Survey: Survey assessing incidence, frequency, and type of illicit substance use via REDCap	Parents Parents of the adolescent participants
Age First Used Marijuana	16 years Interval 14.0 to 17.0	—	—

SECONDARY outcome

Timeframe: Baseline

Population: The number of participants that answered yes to the currently or ever used vape pen question.

Adolescents were asked in a REDCap survey When was the last time you vaped?

Outcome measures

Measure	Overall n=40 Participants Total responses from both participants and parents.	Adolescents Patients 12-21 years undergoing anesthetic care Survey: Survey assessing incidence, frequency, and type of illicit substance use via REDCap	Parents Parents of the adolescent participants
Most Recent Vape Pen Use Not currently using	11 Participants	—	—
Most Recent Vape Pen Use Within the last 24 hours	10 Participants	—	—
Most Recent Vape Pen Use Within the last week	12 Participants	—	—
Most Recent Vape Pen Use Within the last year	7 Participants	—	—

SECONDARY outcome

Timeframe: Baseline

Population: The number of participants that answered yes to the currently or ever vaped question.

Adolescents were asked in a REDCap survey How old were you when you first started vaping?

Outcome measures

Measure	Overall n=40 Participants Total responses from both participants and parents.	Adolescents Patients 12-21 years undergoing anesthetic care Survey: Survey assessing incidence, frequency, and type of illicit substance use via REDCap	Parents Parents of the adolescent participants
Age First Started Vaping	15.5 years Interval 14.0 to 16.0	—	—

SECONDARY outcome

Timeframe: Baseline

Population: The number of participants that answered yes to the currently or ever used tobacco question.

Adolescents were asked in a REDCap survey When was the last time you used tobacco?

Outcome measures

Measure	Overall n=12 Participants Total responses from both participants and parents.	Adolescents Patients 12-21 years undergoing anesthetic care Survey: Survey assessing incidence, frequency, and type of illicit substance use via REDCap	Parents Parents of the adolescent participants
Most Recent Tobacco Use Not currently using	5 Participants	—	—
Most Recent Tobacco Use Within the last 24 hours	3 Participants	—	—
Most Recent Tobacco Use Within the last week	2 Participants	—	—
Most Recent Tobacco Use Within the last year	2 Participants	—	—

SECONDARY outcome

Timeframe: Baseline

Population: The number of participants that answered yes to the currently or ever used tobacco question.

Adolescents were asked in a REDCap survey How old were you when you started using tobacco?

Outcome measures

Measure	Overall n=12 Participants Total responses from both participants and parents.	Adolescents Patients 12-21 years undergoing anesthetic care Survey: Survey assessing incidence, frequency, and type of illicit substance use via REDCap	Parents Parents of the adolescent participants
Age First Used Tobacco	15 years Interval 14.0 to 15.5	—	—

SECONDARY outcome

Timeframe: Baseline

Population: The number of participants that answered yes to the currently or have ever used a prescribed opioid for acute pain question.

Adolescents were asked in a REDCap survey When was the last time you used a prescribed opioid for acute pain?

Outcome measures

Measure	Overall n=35 Participants Total responses from both participants and parents.	Adolescents Patients 12-21 years undergoing anesthetic care Survey: Survey assessing incidence, frequency, and type of illicit substance use via REDCap	Parents Parents of the adolescent participants
Most Recent Prescribed Opioid Use Not currently using	13 Participants	—	—
Most Recent Prescribed Opioid Use Within the last 24 hours	3 Participants	—	—
Most Recent Prescribed Opioid Use Within the last year	15 Participants	—	—
Most Recent Prescribed Opioid Use No answer	1 Participants	—	—
Most Recent Prescribed Opioid Use Within the last week	3 Participants	—	—

SECONDARY outcome

Timeframe: Baseline

Population: The number of participants that answered yes to the currently or ever used prescribed opioid for acute pain question.

Adolescents were asked in a REDCap survey Did you ever use that medication (prescribed opioid) for anything other than pain?

Outcome measures

Measure	Overall n=35 Participants Total responses from both participants and parents.	Adolescents Patients 12-21 years undergoing anesthetic care Survey: Survey assessing incidence, frequency, and type of illicit substance use via REDCap	Parents Parents of the adolescent participants
Prescribed Opioid Use for Anything Other Than Pain No	33 Participants	—	—
Prescribed Opioid Use for Anything Other Than Pain Yes	2 Participants	—	—

SECONDARY outcome

Timeframe: Baseline

Population: The number of participants that answered yes to the currently or ever used prescribed opioid for acute pain question.

Adolescents were asked in a REDCap survey Did your using prescribed opioid for anything other than pain lead to your abusing opioids/narcotics?

Outcome measures

Measure	Overall n=35 Participants Total responses from both participants and parents.	Adolescents Patients 12-21 years undergoing anesthetic care Survey: Survey assessing incidence, frequency, and type of illicit substance use via REDCap	Parents Parents of the adolescent participants
Prescribed Opioid Use Leading to Abuse No	34 Participants	—	—
Prescribed Opioid Use Leading to Abuse Yes	1 Participants	—	—

Adverse Events

Adolescents

Serious events: 0 serious events

Other events: 0 other events

Deaths: 0 deaths

Serious adverse events

Adverse event data not reported

Other adverse events

Adverse event data not reported

Additional Information

Dr. Joseph D. Tobias

Nationwide Children's Hospital

Phone: 614-722-4200

Email: joseph.tobias@nationwidechildrens.org

Results disclosure agreements

• Principal investigator is a sponsor employee
• Publication restrictions are in place