Treatment of Tendinosis Using the TenJet Hydroresection System

NCT ID: NCT05352139

Last Updated: 2024-06-21

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

ENROLLING_BY_INVITATION

Total Enrollment

600 participants

Study Classification

OBSERVATIONAL

Study Start Date

2022-05-01

Study Completion Date

2025-04-30

Brief Summary

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Treatment of recalcitrant tendinopathy remains a clinical challenge for physicians without a minimally invasive treatment option that can consistently provide patients with a long-term relief from chronic pain and ability to return to function.

Surgical debridement of degenerative tendon tissue has long been the standard of care to treat degenerative tendon pathology once all conservative or minimally invasive treatment options have failed.

Ultrasound guided tenotomy is an emerging treatment option with the potential to address the underlying degenerative, diseased tissue, by selectively resecting and removing the tissue in a minimally invasive manner. Additionally, with the availability of in-office diagnostic ultrasound imaging, physicians now have an opportunity to evaluate and classify underlying tendon pathology during a clinical exam. This study is to evaluate outcomes in patients presenting with a clinical history of recalcitrant tendinopathy with confirmed diagnosis of degenerative tendinosis using diagnostic ultrasound imaging or MRI.

Detailed Description

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Conditions

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Tendinopathy Tendinosis

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

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Elbow Tendinosis (Epicondylitis)

Treatment of participants who present with either lateral or medial epicondylitis

Resection (removal) of the degenerative tissue using the Hydrocision TenJet system

Intervention Type PROCEDURE

During the procedure, the TenJet device will remove degenerative tendinopathic tissue using pressurized saline without causing harm to the healthy tendon fibers.

Hydrocision Tenjet System

Intervention Type DEVICE

The TenJet system will be used during surgery to remove the damaged tissue from the joint

Hip Tendinosis (Gluteal Tendinopathy)

Treatment of participants diagnosed with Recalcitrant Gluteal Tendinopathy

Resection (removal) of the degenerative tissue using the Hydrocision TenJet system

Intervention Type PROCEDURE

During the procedure, the TenJet device will remove degenerative tendinopathic tissue using pressurized saline without causing harm to the healthy tendon fibers.

Hydrocision Tenjet System

Intervention Type DEVICE

The TenJet system will be used during surgery to remove the damaged tissue from the joint

Shoulder Calcific Tendinosis (Calcific Shoulder Tendinopathy)

Treatment of participants diagnosed with Calcific Shoulder Tendinopathy

Resection (removal) of the degenerative tissue using the Hydrocision TenJet system

Intervention Type PROCEDURE

During the procedure, the TenJet device will remove degenerative tendinopathic tissue using pressurized saline without causing harm to the healthy tendon fibers.

Hydrocision Tenjet System

Intervention Type DEVICE

The TenJet system will be used during surgery to remove the damaged tissue from the joint

Interventions

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Resection (removal) of the degenerative tissue using the Hydrocision TenJet system

During the procedure, the TenJet device will remove degenerative tendinopathic tissue using pressurized saline without causing harm to the healthy tendon fibers.

Intervention Type PROCEDURE

Hydrocision Tenjet System

The TenJet system will be used during surgery to remove the damaged tissue from the joint

Intervention Type DEVICE

Eligibility Criteria

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Inclusion Criteria

* Patient is 18 - 70 years of age
* Chronic tendon pain ≥ 3 months duration
* History and clinical examination consistent with tendinosis
* Sonographic or MRI confirmation of tendinosis
* 3 months of conservative treatment
* Patient is willing and able to provide informed consent and comply with the study protocol

Exclusion Criteria

* Full thickness tear of the tendon
* Unable to withhold anticoagulants 7 days prior to the procedure.
* Use above 81mg/day of acetylsalicyclic acid (ASA) and/or non-steroidal anti-inflammatory drug (NSAID) within 7 days of treatment
* Steroid, PRP, Stem cell or biologic injections within 3 months of the study procedure date
* Needle tenotomy, Tenex, or surgical interventions within 6 months of study procedure date
* Active local or systemic infection requiring antiviral, antibacterial or antifungal treatment
* Chronic conditions such as CRPS or fibromyalgia that might affect pain symptoms.
Minimum Eligible Age

18 Years

Maximum Eligible Age

70 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Rothman Institute Orthopaedics

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Locations

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Standford Medicine

Redwood City, California, United States

Site Status

Cleveland Clinic

Coral Springs, Florida, United States

Site Status

Ochsner Health

Baton Rouge, Louisiana, United States

Site Status

University of North Carolina

Chapel Hill, North Carolina, United States

Site Status

Cleveland Clinic

Lorain, Ohio, United States

Site Status

Penn Highlands Orthopedics and Sports Medicine

Clarion, Pennsylvania, United States

Site Status

Rothman Orthopaedic Institute

Philadelphia, Pennsylvania, United States

Site Status

Countries

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United States

Other Identifiers

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WIRB CMEH 01

Identifier Type: -

Identifier Source: org_study_id

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