Trial Outcomes & Findings for Loving Kindness Meditation Among Adults 50 Years and Older (NCT NCT05350449)
NCT ID: NCT05350449
Last Updated: 2025-07-04
Results Overview
A 3-item modified UCLA loneliness scale will be used to measure loneliness. The scores on this scale range from 3 to 9, the highest scores indicative of a higher level of loneliness. We will measure loneliness at baseline, post-intervention and 2 follow-up periods to measure the change in loneliness level because of the loving-kindness meditation intervention.
Recruitment status
COMPLETED
Study phase
NA
Target enrollment
59 participants
Primary outcome timeframe
baseline, immediately post-intervention, and week 4 and week 8 post intervention (follow-up periods).
Results posted on
2025-07-04
Participant Flow
Participant milestones
| Measure |
Loving Kindness Meditation
Loving-kindness meditation is a contemplative practice that focuses on developing compassion for oneself and others through mindfulness. Participants will be shown the recorded loving-kindness training video during the first week of the intervention. Participants will be encouraged to use the mp3 device with guided meditation recording to practice mindfulness meditation for 20-25 minutes every day for 30 days. We will also provide participants with a diary to record their daily meditation experiences. There will be weekly check in. At 60 days we will do a follow-up data collection.
Loving-kindness Meditation: Loving-kindness meditation is a type of mindfulness practice where the focus is on love/compassion and kindness for self and others. The guided meditation will be provided via recording device. The intervention is 4 week long.
22 participants
|
Waitlist Control
The arm will eventually get the intervention.
23 participants
|
|---|---|---|
|
Overall Study
STARTED
|
28
|
31
|
|
Overall Study
COMPLETED
|
24
|
23
|
|
Overall Study
NOT COMPLETED
|
4
|
8
|
Reasons for withdrawal
| Measure |
Loving Kindness Meditation
Loving-kindness meditation is a contemplative practice that focuses on developing compassion for oneself and others through mindfulness. Participants will be shown the recorded loving-kindness training video during the first week of the intervention. Participants will be encouraged to use the mp3 device with guided meditation recording to practice mindfulness meditation for 20-25 minutes every day for 30 days. We will also provide participants with a diary to record their daily meditation experiences. There will be weekly check in. At 60 days we will do a follow-up data collection.
Loving-kindness Meditation: Loving-kindness meditation is a type of mindfulness practice where the focus is on love/compassion and kindness for self and others. The guided meditation will be provided via recording device. The intervention is 4 week long.
22 participants
|
Waitlist Control
The arm will eventually get the intervention.
23 participants
|
|---|---|---|
|
Overall Study
Withdrawal by Subject
|
4
|
8
|
Baseline Characteristics
Loving Kindness Meditation Among Adults 50 Years and Older
Baseline characteristics by cohort
| Measure |
Loving Kindness Meditation
n=28 Participants
Loving-kindness meditation is a contemplative practice that focuses on developing compassion for oneself and others through mindfulness. Participants will be shown the recorded loving-kindness training video during the first week of the intervention. Participants will be encouraged to use the mp3 device with guided meditation recording to practice mindfulness meditation for 20-25 minutes every day for 30 days. We will also provide participants with a diary to record their daily meditation experiences. There will be weekly check in. At 60 days we will do a follow-up data collection.
Loving-kindness Meditation: Loving-kindness meditation is a type of mindfulness practice where the focus is on love/compassion and kindness for self and others. The guided meditation will be provided via recording device. The intervention is 4 week long.
|
Waitlist Control
n=31 Participants
The arm will eventually get the intervention.
|
Total
n=59 Participants
Total of all reporting groups
|
|---|---|---|---|
|
Age, Continuous
|
74.1 Years
STANDARD_DEVIATION 6.2 • n=5 Participants
|
71.5 Years
STANDARD_DEVIATION 6.9 • n=7 Participants
|
72.8 Years
STANDARD_DEVIATION 6.6 • n=5 Participants
|
|
Sex: Female, Male
Female
|
19 Participants
n=5 Participants
|
25 Participants
n=7 Participants
|
44 Participants
n=5 Participants
|
|
Sex: Female, Male
Male
|
9 Participants
n=5 Participants
|
6 Participants
n=7 Participants
|
15 Participants
n=5 Participants
|
|
Ethnicity (NIH/OMB)
Hispanic or Latino
|
2 Participants
n=5 Participants
|
5 Participants
n=7 Participants
|
7 Participants
n=5 Participants
|
|
Ethnicity (NIH/OMB)
Not Hispanic or Latino
|
24 Participants
n=5 Participants
|
25 Participants
n=7 Participants
|
49 Participants
n=5 Participants
|
|
Ethnicity (NIH/OMB)
Unknown or Not Reported
|
2 Participants
n=5 Participants
|
1 Participants
n=7 Participants
|
3 Participants
n=5 Participants
|
|
Race (NIH/OMB)
American Indian or Alaska Native
|
0 Participants
n=5 Participants
|
0 Participants
n=7 Participants
|
0 Participants
n=5 Participants
|
|
Race (NIH/OMB)
Asian
|
1 Participants
n=5 Participants
|
0 Participants
n=7 Participants
|
1 Participants
n=5 Participants
|
|
Race (NIH/OMB)
Native Hawaiian or Other Pacific Islander
|
1 Participants
n=5 Participants
|
0 Participants
n=7 Participants
|
1 Participants
n=5 Participants
|
|
Race (NIH/OMB)
Black or African American
|
4 Participants
n=5 Participants
|
2 Participants
n=7 Participants
|
6 Participants
n=5 Participants
|
|
Race (NIH/OMB)
White
|
20 Participants
n=5 Participants
|
25 Participants
n=7 Participants
|
45 Participants
n=5 Participants
|
|
Race (NIH/OMB)
More than one race
|
2 Participants
n=5 Participants
|
0 Participants
n=7 Participants
|
2 Participants
n=5 Participants
|
|
Race (NIH/OMB)
Unknown or Not Reported
|
0 Participants
n=5 Participants
|
4 Participants
n=7 Participants
|
4 Participants
n=5 Participants
|
|
Region of Enrollment
United States
|
28 participants
n=5 Participants
|
31 participants
n=7 Participants
|
54 participants
n=5 Participants
|
|
Loneliness
|
4.6 units on a scale
STANDARD_DEVIATION 1.6 • n=5 Participants
|
4.7 units on a scale
STANDARD_DEVIATION 1.9 • n=7 Participants
|
4.7 units on a scale
STANDARD_DEVIATION 1.8 • n=5 Participants
|
PRIMARY outcome
Timeframe: baseline, immediately post-intervention, and week 4 and week 8 post intervention (follow-up periods).Population: Baseline population
A 3-item modified UCLA loneliness scale will be used to measure loneliness. The scores on this scale range from 3 to 9, the highest scores indicative of a higher level of loneliness. We will measure loneliness at baseline, post-intervention and 2 follow-up periods to measure the change in loneliness level because of the loving-kindness meditation intervention.
Outcome measures
| Measure |
Loving Kindness Meditation
n=28 Participants
Loving-kindness meditation is a contemplative practice that focuses on developing compassion for oneself and others through mindfulness. Participants will be shown the recorded loving-kindness training video during the first week of the intervention. Participants will be encouraged to use the mp3 device with guided meditation recording to practice mindfulness meditation for 20-25 minutes every day for 30 days. We will also provide participants with a diary to record their daily meditation experiences. There will be weekly check in. At 60 days we will do a follow-up data collection.
Loving-kindness Meditation: Loving-kindness meditation is a type of mindfulness practice where the focus is on love/compassion and kindness for self and others. The guided meditation will be provided via recording device. The intervention is 4 week long.
22 participants
|
Waitlist Control
n=31 Participants
The arm will eventually get the intervention.
23 participants
|
|---|---|---|
|
Change in Loneliness
Baseline
|
4.64 units on a scale
Standard Deviation 1.64
|
4.65 units on a scale
Standard Deviation 1.85
|
|
Change in Loneliness
Post-Intervention
|
4.82 units on a scale
Standard Deviation 1.68
|
4.62 units on a scale
Standard Deviation 1.69
|
|
Change in Loneliness
Week 4 follow up
|
4.56 units on a scale
Standard Deviation 1.48
|
4.55 units on a scale
Standard Deviation 1.82
|
|
Change in Loneliness
Week 8 follow up
|
4.74 units on a scale
Standard Deviation 1.85
|
4.09 units on a scale
Standard Deviation 1.63
|
PRIMARY outcome
Timeframe: baseline, immediately post-intervention, and week 4 and week 8 post intervention.Population: Baseline
A 12-item Self-compassion Short form Scale by Kirsten Neff will be used to measure self-compassion. The scores on this scale rages from 1-5. The highest scores are indicative of better self-compassion. We will measure self-compassion at baseline and post-intervention periods to measure the change in self-compassion because of the loving-kindness meditation intervention.
Outcome measures
| Measure |
Loving Kindness Meditation
n=28 Participants
Loving-kindness meditation is a contemplative practice that focuses on developing compassion for oneself and others through mindfulness. Participants will be shown the recorded loving-kindness training video during the first week of the intervention. Participants will be encouraged to use the mp3 device with guided meditation recording to practice mindfulness meditation for 20-25 minutes every day for 30 days. We will also provide participants with a diary to record their daily meditation experiences. There will be weekly check in. At 60 days we will do a follow-up data collection.
Loving-kindness Meditation: Loving-kindness meditation is a type of mindfulness practice where the focus is on love/compassion and kindness for self and others. The guided meditation will be provided via recording device. The intervention is 4 week long.
22 participants
|
Waitlist Control
n=31 Participants
The arm will eventually get the intervention.
23 participants
|
|---|---|---|
|
Change in Self-compassion
Baseline
|
3.5 units on a scale
Standard Error 0.63
|
3.62 units on a scale
Standard Error 0.87
|
|
Change in Self-compassion
Post-intervention
|
3.29 units on a scale
Standard Error 0.75
|
3.61 units on a scale
Standard Error 0.92
|
|
Change in Self-compassion
Week 4 follow-up
|
3.43 units on a scale
Standard Error 0.66
|
3.82 units on a scale
Standard Error 0.98
|
|
Change in Self-compassion
Week 8 follow-up
|
3.6 units on a scale
Standard Error 0.75
|
4.03 units on a scale
Standard Error 1.02
|
SECONDARY outcome
Timeframe: baseline, immediately post-intervention, and week 4 and week 8 post intervention.Population: Some of participants did not enter the data for some timelines.
A 4-item PROMIS Emotional Distress: Anxiety Scale will be used to measure anxiety. The scores on this scale range from 4 to 20, the highest scores indicative of a higher feeling of anxiety. We will measure anxiety at baseline and post-intervention periods to measure the change in anxiety level because of the loving-kindness meditation intervention.
Outcome measures
| Measure |
Loving Kindness Meditation
n=28 Participants
Loving-kindness meditation is a contemplative practice that focuses on developing compassion for oneself and others through mindfulness. Participants will be shown the recorded loving-kindness training video during the first week of the intervention. Participants will be encouraged to use the mp3 device with guided meditation recording to practice mindfulness meditation for 20-25 minutes every day for 30 days. We will also provide participants with a diary to record their daily meditation experiences. There will be weekly check in. At 60 days we will do a follow-up data collection.
Loving-kindness Meditation: Loving-kindness meditation is a type of mindfulness practice where the focus is on love/compassion and kindness for self and others. The guided meditation will be provided via recording device. The intervention is 4 week long.
22 participants
|
Waitlist Control
n=31 Participants
The arm will eventually get the intervention.
23 participants
|
|---|---|---|
|
Change in Anxiety
baseline
|
8.33 units on a scale
Standard Deviation 3.34
|
8.61 units on a scale
Standard Deviation 3.87
|
|
Change in Anxiety
post intervention
|
8.89 units on a scale
Standard Deviation 3.2
|
9.54 units on a scale
Standard Deviation 3.85
|
|
Change in Anxiety
week 4 follow-up
|
7.76 units on a scale
Standard Deviation 3.26
|
8.33 units on a scale
Standard Deviation 3.95
|
|
Change in Anxiety
week 8 follow-up
|
8.54 units on a scale
Standard Deviation 4.01
|
7.5 units on a scale
Standard Deviation 3.64
|
SECONDARY outcome
Timeframe: baseline, immediately post-intervention, and week 4 and week 8 post intervention.Population: not all participants entered data for each timeline.
A 10-item Center for Epidemiologic Studies Short Depression Scale will be used to measure depressive symptoms. The scores on this scale range from 10 to 40, the highest scores indicative of a higher feeling of depression. We will measure depressive symptoms at baseline and post-intervention periods to measure the change in depressive symptoms because of the loving-kindness meditation intervention.
Outcome measures
| Measure |
Loving Kindness Meditation
n=28 Participants
Loving-kindness meditation is a contemplative practice that focuses on developing compassion for oneself and others through mindfulness. Participants will be shown the recorded loving-kindness training video during the first week of the intervention. Participants will be encouraged to use the mp3 device with guided meditation recording to practice mindfulness meditation for 20-25 minutes every day for 30 days. We will also provide participants with a diary to record their daily meditation experiences. There will be weekly check in. At 60 days we will do a follow-up data collection.
Loving-kindness Meditation: Loving-kindness meditation is a type of mindfulness practice where the focus is on love/compassion and kindness for self and others. The guided meditation will be provided via recording device. The intervention is 4 week long.
22 participants
|
Waitlist Control
n=31 Participants
The arm will eventually get the intervention.
23 participants
|
|---|---|---|
|
Change in Depressive Symptoms
baseline
|
16.72 units on a scale
Standard Deviation 5.32
|
17.04 units on a scale
Standard Deviation 5.65
|
|
Change in Depressive Symptoms
post-intervention
|
18.21 units on a scale
Standard Deviation 4.79
|
18.12 units on a scale
Standard Deviation 6.34
|
|
Change in Depressive Symptoms
week 4 follow-up
|
16.74 units on a scale
Standard Deviation 5.01
|
16.14 units on a scale
Standard Deviation 6.11
|
|
Change in Depressive Symptoms
week 8 follow-up
|
18.07 units on a scale
Standard Deviation 7.09
|
15.50 units on a scale
Standard Deviation 5.73
|
Adverse Events
Loving Kindness Meditation
Serious events: 0 serious events
Other events: 0 other events
Deaths: 0 deaths
Waitlist Control
Serious events: 0 serious events
Other events: 0 other events
Deaths: 0 deaths
Serious adverse events
Adverse event data not reported
Other adverse events
Adverse event data not reported
Additional Information
Results disclosure agreements
- Principal investigator is a sponsor employee
- Publication restrictions are in place