Trial Outcomes & Findings for The Feasibility of Engage Therapy With Video Support for Homebound Older Adults (NCT NCT05346055)

Results Overview

The CSQ is a 3 - item questionnaire assessing client satisfaction with the treatment provided partway through the treatment (6 weeks). Scores range from 3 (least satisfied) to 12 (most satisfied).

Recruitment status

COMPLETED

Study phase

NA

Target enrollment

8 participants

Primary outcome timeframe

6 weeks (part-way through treatment)

Results posted on

2023-06-28

Participant Flow

Participants were recruited from the Virtual Senior Center, a community-building platform that helps older and homebound adults connect and engage with each other through virtual and hybrid classes. Recruitment efforts included online message board posts, emails, and virtual information sessions (via Zoom). Prospective participants contacted a study team member via phone or email and completed screening via phone. Participants were recruited between April 1, 2022 and June 30, 2022.

Participant milestones

Participant milestones
Measure	Engage Prism 2.0 Engage Prism is a 9-week program that integrates Engage- a form of behavioral talk therapy treating depression, and guided use of Prism technology- a software that aims to improve social support and interaction of older adults. Engage Prism (2.0): Brief Behavioral Treatment for Depression (Engage) combined with tablet-based social support system (Prism 2.0)
Overall Study STARTED	8
Overall Study COMPLETED	5
Overall Study NOT COMPLETED	3

Reasons for withdrawal

Reasons for withdrawal
Measure	Engage Prism 2.0 Engage Prism is a 9-week program that integrates Engage- a form of behavioral talk therapy treating depression, and guided use of Prism technology- a software that aims to improve social support and interaction of older adults. Engage Prism (2.0): Brief Behavioral Treatment for Depression (Engage) combined with tablet-based social support system (Prism 2.0)
Overall Study Withdrawal by Subject	1
Overall Study Protocol Violation	1
Overall Study Therapist decision	1

Baseline Characteristics

The Feasibility of Engage Therapy With Video Support for Homebound Older Adults

Baseline characteristics by cohort

Baseline characteristics by cohort
Measure	Engage Prism 2.0 n=8 Participants Engage Prism is a 9-week program that integrates Engage- a form of behavioral talk therapy treating depression, and guided use of Prism technology- a software that aims to improve social support and interaction of older adults. Engage Prism (2.0): Brief Behavioral Treatment for Depression (Engage) combined with tablet-based social support system (Prism 2.0)
Age, Continuous	73.88 years STANDARD_DEVIATION 6.58 • n=5 Participants
Sex: Female, Male Female	6 Participants n=5 Participants
Sex: Female, Male Male	2 Participants n=5 Participants
Race/Ethnicity, Customized White	7 Participants n=5 Participants
Race/Ethnicity, Customized Black/African American	1 Participants n=5 Participants
Region of Enrollment United States	8 participants n=5 Participants

PRIMARY outcome

Timeframe: 6 weeks (part-way through treatment)

Population: All participants completing the study were analyzed, although one participant is not included due to a database error. Those who did not complete the study could not complete the post-study CSQ.

The CSQ is a 3 - item questionnaire assessing client satisfaction with the treatment provided partway through the treatment (6 weeks). Scores range from 3 (least satisfied) to 12 (most satisfied).

Outcome measures

Outcome measures
Measure	Engage Prism 2.0 n=4 Participants Engage Prism is a 9-week program that integrates Engage- a form of behavioral talk therapy treating depression, and guided use of Prism technology- a software that aims to improve social support and interaction of older adults. Engage Prism (2.0): Brief Behavioral Treatment for Depression (Engage) combined with tablet-based social support system (Prism 2.0)
Acceptability: Client Satisfaction Questionnaire (CSQ)	10.5 score on a scale Standard Deviation 4.34

PRIMARY outcome

Timeframe: 12 weeks (post treatment)

Population: Five total participants completed the study and 12-week follow up. Only 2 are included as three records were lost due to a databases error.

The CSQ is a 3 - item questionnaire assessing client satisfaction with the treatment provided assessed at 3 weeks post treatment (at 12 weeks) Scores range from 3 (least satisfied) to 12 (most satisfied).

Outcome measures

Outcome measures
Measure	Engage Prism 2.0 n=2 Participants Engage Prism is a 9-week program that integrates Engage- a form of behavioral talk therapy treating depression, and guided use of Prism technology- a software that aims to improve social support and interaction of older adults. Engage Prism (2.0): Brief Behavioral Treatment for Depression (Engage) combined with tablet-based social support system (Prism 2.0)
Acceptability: Client Satisfaction Questionnaire (CSQ)	9 score on a scale Standard Deviation 0

PRIMARY outcome

Timeframe: Baseline

Feasibility will be measured as the number of clients who are referred to the program, meet eligibility and accept the intervention (versus refuse).

Outcome measures

Outcome measures
Measure	Engage Prism 2.0 n=8 Participants Engage Prism is a 9-week program that integrates Engage- a form of behavioral talk therapy treating depression, and guided use of Prism technology- a software that aims to improve social support and interaction of older adults. Engage Prism (2.0): Brief Behavioral Treatment for Depression (Engage) combined with tablet-based social support system (Prism 2.0)
Feasibility: Client Enrollment	8 Participants

SECONDARY outcome

Timeframe: Baseline, 9 weeks (end of treatment)

Population: Five participants completed this phase of the treatment, but only 3 are included as 2 were lost due to a database error.

Change in depression scores from Baseline to 9 weeks. Scores range from 0 (no depression) to 54 (very severe depression).

Outcome measures

Outcome measures
Measure	Engage Prism 2.0 n=3 Participants Engage Prism is a 9-week program that integrates Engage- a form of behavioral talk therapy treating depression, and guided use of Prism technology- a software that aims to improve social support and interaction of older adults. Engage Prism (2.0): Brief Behavioral Treatment for Depression (Engage) combined with tablet-based social support system (Prism 2.0)
Hamilton Depression Rating Scale	8.67 difference in pre/post score on a scale Standard Deviation 2.52

SECONDARY outcome

Timeframe: Baseline, 12 weeks (post treatment)

Population: Five participants completed this phase of the treatment, but only 2 are included as 3 were lost due to a database error.

Change in depression score from Baseline to 12 weeks post treatment. Scores range from 0 (no depression) to 54 (very severe depression).

Outcome measures

Outcome measures
Measure	Engage Prism 2.0 n=2 Participants Engage Prism is a 9-week program that integrates Engage- a form of behavioral talk therapy treating depression, and guided use of Prism technology- a software that aims to improve social support and interaction of older adults. Engage Prism (2.0): Brief Behavioral Treatment for Depression (Engage) combined with tablet-based social support system (Prism 2.0)
Hamilton Depression Rating Scale	0.5 difference in pre/post score on a scale Standard Deviation 0.707

Adverse Events

Engage Prism 2.0

Serious events: 0 serious events

Other events: 0 other events

Deaths: 0 deaths

Serious adverse events

Adverse event data not reported

Other adverse events

Adverse event data not reported

Additional Information

Jo Anne Sirey

Weill Cornell Medical College

Phone: 914-997-4333

Email: [email protected]

Results disclosure agreements

Principal investigator is a sponsor employee
Publication restrictions are in place