Dialectal Behaviour Therapy to Enhance Health Behaviour Change for Adolescents Living With Obesity (DIRECTION Trial)

NCT ID: NCT05338944

Last Updated: 2025-10-07

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Clinical Phase

NA

Total Enrollment

90 participants

Study Classification

INTERVENTIONAL

Study Start Date

2023-01-14

Study Completion Date

2027-01-31

Brief Summary

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This research is being conducted to evaluate emotion-focused therapy that incorporates elements of mindfulness, distress tolerance, and relationship support. The investigators want to learn if this therapy, called Dialectical Behavioral Therapy (DBT) will help improve quality of life and weight management in youth at risk for type 2 diabetes. Individuals will be randomly assigned to weekly group based session in one of 3 intervention arms; lifestyle + DBT, lifestyle alone, or a control arm.

Detailed Description

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Conditions

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Prevention Type2Diabetes

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

90 youth will be randomized (2:2:1) into one of the three arms of the trial; DBT + lifestyle, lifestyle alone, control
Primary Study Purpose

PREVENTION

Blinding Strategy

NONE

Study Groups

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DBT + lifestyle

Participants will receive 90 minutes of dialectical behavioral therapy and 90 minutes of lifestyle sessions each week for 16 weeks.

Group Type EXPERIMENTAL

Dialectical behavioral therapy

Intervention Type BEHAVIORAL

Working with psychologists through DBT skills training.

Lifestyle

Intervention Type BEHAVIORAL

Working with kinesiologist and registered dietician to improve lifestyle habits.

Lifestyle alone

Participants will receive 2 lifestyle sessions per week, 90 minutes each for 16 weeks.

Group Type EXPERIMENTAL

Lifestyle

Intervention Type BEHAVIORAL

Working with kinesiologist and registered dietician to improve lifestyle habits.

Control

Participants will be included in baseline, endpoint and follow up measurements, but will receive no form of intervention.

Group Type NO_INTERVENTION

No interventions assigned to this group

Interventions

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Dialectical behavioral therapy

Working with psychologists through DBT skills training.

Intervention Type BEHAVIORAL

Lifestyle

Working with kinesiologist and registered dietician to improve lifestyle habits.

Intervention Type BEHAVIORAL

Eligibility Criteria

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Inclusion Criteria

* 14-17 years old
* BMI z-score \>1.4
* signs of mild-moderate depression (PHQ-9 score 5-19)
* willing and able to comply with study procedures

Exclusion Criteria

* more than one health co-morbidity
* being treated with medication for obesity
* taking steroids
* currently being treated for atypical antipsychotics
* have an orthopedic injury or chronic illness that would prevent them from performing the intervention
* experienced weight loss or enrolled in weight loss program in the six months prior to the study
* they are currently and/or in the past 12 months have been prescribed any weight loss medication(s) including Ozempic
* self reported history of alcoholism or drug abuse
* history of self-harm or suicide attempts in the past 12 months
* currently enrolled in psychotherapy or DBT
* parents do not approve of you participating
* unable to read, speak and understand English as translation will not be provided
* unable/unwilling to give assent/consent
Minimum Eligible Age

14 Years

Maximum Eligible Age

17 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Diabetes Canada

OTHER

Sponsor Role collaborator

Canadian Institutes of Health Research (CIHR)

OTHER_GOV

Sponsor Role collaborator

University of Manitoba

OTHER

Sponsor Role lead

Responsible Party

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Jon McGavock

Principal Investigator

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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University of Calgary

Calgary, Alberta, Canada

Site Status RECRUITING

University of Manitoba

Winnipeg, Manitoba, Canada

Site Status RECRUITING

McMaster University

Hamilton, Ontario, Canada

Site Status RECRUITING

Countries

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Canada

Central Contacts

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Jon McGavock, PhD

Role: CONTACT

204-789-3591

Jana Slaght, MSc

Role: CONTACT

204-789-3591

Facility Contacts

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Josephine Ho, MD

Role: primary

403-955-7003

Heidi Virtanen, MSc

Role: backup

Jonathan McGavock, PhD

Role: primary

2047893591

Jana Apperley, MSc

Role: backup

2047893591

Katherine Morrison, MD, FRCP

Role: primary

905-521-2100 ext. 75926

Autumn Lawrence, MSc

Role: backup

Other Identifiers

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HS24295

Identifier Type: -

Identifier Source: org_study_id

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