Trial Outcomes & Findings for A Novel Cooling Device for Pain Management During Fingerstick Blood Draw (NCT NCT05329493)

NCT ID: NCT05329493

Last Updated: 2025-02-13

Results Overview

This scale will be used to record subject pain from the overall pain from the procedure for the treatment and control finger. There are 6 faces ranging from 0 no hurt to 10 hurts the worst.

Recruitment status

COMPLETED

Study phase

NA

Target enrollment

6 participants

Primary outcome timeframe

day 1

Results posted on

2025-02-13

Participant Flow

Unit of analysis: fingers

Participant milestones

Participant milestones
Measure
Cooling Digit Device Application
The cooling finger device will be applied to all study participants on their hand (fifth or third finger). The hand picked will be randomized and opposite to that of the control hand. Subjects will serve as their own control.
Control
All study participants will have their fifth or third finger pricked. Subjects will serve as their own control.
Overall Study
STARTED
6 6
6 6
Overall Study
COMPLETED
6 6
6 6
Overall Study
NOT COMPLETED
0 0
0 0

Reasons for withdrawal

Withdrawal data not reported

Baseline Characteristics

A Novel Cooling Device for Pain Management During Fingerstick Blood Draw

Baseline characteristics by cohort

Baseline characteristics by cohort
Measure
Cooling Digit Device Application
n=6 Participants
Device: Cooling digit device. The cooling finger device will be applied in the subjects on their right hand. Subjects will serve as their own control. Cooling digit device application: Cooling digit device will be applied on subject's right hand ( fifth finger).
Age, Categorical
<=18 years
0 Participants
n=5 Participants
Age, Categorical
Between 18 and 65 years
6 Participants
n=5 Participants
Age, Categorical
>=65 years
0 Participants
n=5 Participants
Sex: Female, Male
Female
2 Participants
n=5 Participants
Sex: Female, Male
Male
4 Participants
n=5 Participants
Ethnicity (NIH/OMB)
Hispanic or Latino
0 Participants
n=5 Participants
Ethnicity (NIH/OMB)
Not Hispanic or Latino
6 Participants
n=5 Participants
Ethnicity (NIH/OMB)
Unknown or Not Reported
0 Participants
n=5 Participants
Race (NIH/OMB)
American Indian or Alaska Native
0 Participants
n=5 Participants
Race (NIH/OMB)
Asian
0 Participants
n=5 Participants
Race (NIH/OMB)
Native Hawaiian or Other Pacific Islander
0 Participants
n=5 Participants
Race (NIH/OMB)
Black or African American
0 Participants
n=5 Participants
Race (NIH/OMB)
White
6 Participants
n=5 Participants
Race (NIH/OMB)
More than one race
0 Participants
n=5 Participants
Race (NIH/OMB)
Unknown or Not Reported
0 Participants
n=5 Participants
Region of Enrollment
United States
6 Participants
n=5 Participants

PRIMARY outcome

Timeframe: day 1

This scale will be used to record subject pain from the overall pain from the procedure for the treatment and control finger. There are 6 faces ranging from 0 no hurt to 10 hurts the worst.

Outcome measures

Outcome measures
Measure
Cooling Digit Device Application
n=6 fingers
The cooling finger device will be applied to all study participants on their hand (fifth or third finger). The hand picked will be randomized and opposite to that of the control hand. Subjects will serve as their own control.
Control
n=6 fingers
All study participants will have their fifth or third finger pricked. Subjects will serve as their own control.
Wong-Baker FACES Pain Rating Scale
1.2 score on a scale
Standard Deviation 0.8
2.4 score on a scale
Standard Deviation 0.5

SECONDARY outcome

Timeframe: Day 1

After the finger has been pricked, the finger will subsequently be held over a single-use Whatman 903 filter paper. Approximately every ten seconds after the prick, the filter paper will be gently applied to the blood drop to absorb the blood. This will be repeated on new locations of the filter paper until blood flow stops. At least one Whatman 903 filter paper will be used per finger prick. The Whatman 903 filter paper will be imaged.

Outcome measures

Outcome measures
Measure
Cooling Digit Device Application
n=6 fingers
The cooling finger device will be applied to all study participants on their hand (fifth or third finger). The hand picked will be randomized and opposite to that of the control hand. Subjects will serve as their own control.
Control
n=6 fingers
All study participants will have their fifth or third finger pricked. Subjects will serve as their own control.
Blood Absorption Via Whatman 903 Filter Paper (Surface Area)
1.4 cm^2
Standard Deviation 0.8
1.1 cm^2
Standard Deviation 0.7

SECONDARY outcome

Timeframe: Day 1

After the finger has been pricked, the finger will subsequently be held over a single-use Whatman 903 filter paper. Approximately every ten seconds after the prick, the filter paper will be gently applied to the blood drop to absorb the blood. This will be repeated on new locations of the filter paper until blood flow stops. At least one Whatman 903 filter paper will be used per finger prick. The Whatman 903 filter paper will be imaged.

Outcome measures

Outcome measures
Measure
Cooling Digit Device Application
n=6 fingers
The cooling finger device will be applied to all study participants on their hand (fifth or third finger). The hand picked will be randomized and opposite to that of the control hand. Subjects will serve as their own control.
Control
n=6 fingers
All study participants will have their fifth or third finger pricked. Subjects will serve as their own control.
Blood Absorption Via Whatman 903 Filter Paper (Drops of Blood)
11.4 number of drops
Standard Deviation 2.5
12.4 number of drops
Standard Deviation 8.4

Adverse Events

Cooling Digit Device Application

Serious events: 0 serious events
Other events: 0 other events
Deaths: 0 deaths

Control

Serious events: 0 serious events
Other events: 0 other events
Deaths: 0 deaths

Serious adverse events

Adverse event data not reported

Other adverse events

Adverse event data not reported

Additional Information

Dr. Dieter Manstein

Massachusetts General Hospital

Phone: 617-726-4893

Results disclosure agreements

  • Principal investigator is a sponsor employee
  • Publication restrictions are in place