Effects of Systemic Drugs on Intraocular Pressure

NCT ID: NCT05328921

Last Updated: 2022-04-14

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Total Enrollment

200 participants

Study Classification

OBSERVATIONAL

Study Start Date

2022-04-07

Study Completion Date

2022-09-30

Brief Summary

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To assess intraocular pressure changes among glaucoma patients on systemic antihypertensive and antihistaminic drugs.

Detailed Description

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Changes in intraocular pressure in glaucomatous patients with narrow angle may elicit attacks of angle closure glaucoma.

In this study we aim to assess changes in intraocular pressure (IOP) among glaucomatous patients on systemic antihypertensive and antihistaminic drugs.

Conditions

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Glaucoma, Angle-Closure Glaucoma Suspect Glaucoma Secondary to Drugs, Bilateral Hypertension

Study Design

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Observational Model Type

CASE_ONLY

Study Time Perspective

CROSS_SECTIONAL

Study Groups

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Antihypertensive drugs group

Changes in IOP among patients on antihypertensive drugs

Antihypertensive Agents

Intervention Type DRUG

Patients with narrow angle glaucoma and on systemic antihypertensive drugs.

Antihistaminic drugs group

Changes in IOP among patients on antihistaminic drugs

Antihistaminics

Intervention Type DRUG

Patients with narrow angle glaucoma and on systemic antihistaminic drugs.

Antihypertensive and antihistaminic drugs group

Changes in IOP among patients on both antihypertensive and antihistaminic drugs

Antihypertensive Agents

Intervention Type DRUG

Patients with narrow angle glaucoma and on systemic antihypertensive drugs.

Antihistaminics

Intervention Type DRUG

Patients with narrow angle glaucoma and on systemic antihistaminic drugs.

Interventions

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Antihypertensive Agents

Patients with narrow angle glaucoma and on systemic antihypertensive drugs.

Intervention Type DRUG

Antihistaminics

Patients with narrow angle glaucoma and on systemic antihistaminic drugs.

Intervention Type DRUG

Eligibility Criteria

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Inclusion Criteria

* patients with narrow angle glaucoma on systemic antihypertensive and/or antihistaminic drugs.

Exclusion Criteria

* open angle glaucoma patients confirmed by gonioscopy examination.
* Cases with dense corneal opacity or iris trauma that may affects gonioscopy examination.
* cases with secondary glaucoma.
Minimum Eligible Age

35 Years

Maximum Eligible Age

70 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Benha University

OTHER

Sponsor Role lead

Responsible Party

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Ahmed Abdelshafy

Lecturer of Ophthalmology

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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Ahmed Abdelshafy

Banhā, QA, Egypt

Site Status RECRUITING

Countries

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Egypt

Central Contacts

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Ahmed Abdelshafy, MD

Role: CONTACT

01222328766

Marwa Abdelshafy, MD

Role: CONTACT

01222328766

Facility Contacts

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Ahmed Abdelshafy, MD

Role: primary

01222328766

Marwa Abdelshafy, MD

Role: backup

01222328766 ext. Abdelshafy

Other Identifiers

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Rc 9-22

Identifier Type: -

Identifier Source: org_study_id

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