Evaluating a Community-Based Behaviour Change Communication Model to Prevent Cholangiocarcinoma in Khon Kaen, Thailand

NCT ID: NCT05321992

Last Updated: 2024-11-21

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Clinical Phase

NA

Total Enrollment

480 participants

Study Classification

INTERVENTIONAL

Study Start Date

2024-06-05

Study Completion Date

2026-04-01

Brief Summary

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Liver cancer, specifically cholangiocarcinoma (CCA), is very common in different areas in Thailand. Many factors make this cancer more common, such as liver fluke infection, older age, eating raw fish, family history of cancer, alcohol intake, taking certain medicines (praziquantel), low intake of fresh vegetable, and low education. In 2015, researchers from Khon Kaen University developed the Community-based Health Education and Communication (CHEC) program to prevent liver cancer caused by liver flukes in communities of the Khon Kaen province, Thailand.

The main aim of this 5-year research study is to enhance the CHEC program to prevent liver cancer, and test if it is effective in improving the knowledge and behaviours of community residents regarding how to prevent liver cancer. This study will take place in Khon Kaen, Thailand. Other aims are to:

1. Increase understanding in the community that make it difficult to prevent liver cancer, as well as community characteristics that can help prevent liver cancer;
2. Incorporate the program we develop in healthcare to prevent liver cancer in Thailand.

Detailed Description

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Conditions

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Cholangiocarcinoma Liver Fluke-Related Cholangiocarcinoma Opisthorchiasis

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

PREVENTION

Blinding Strategy

NONE

Study Groups

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Usual Care Community

Participants in this arm will not be given the eCHEC program

Group Type NO_INTERVENTION

No interventions assigned to this group

eCHEC Community

Participants in this arm will be given the eCHEC program as their intervention

Group Type ACTIVE_COMPARATOR

eCHEC program

Intervention Type BEHAVIORAL

The eCHEC program is the enhanced Community-based Health Education and Communication (CHEC) model to prevent O. viverrini in an effort to decrease cholangiocarcinoma (CCA) in Khon Kaen, Thailand

Interventions

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eCHEC program

The eCHEC program is the enhanced Community-based Health Education and Communication (CHEC) model to prevent O. viverrini in an effort to decrease cholangiocarcinoma (CCA) in Khon Kaen, Thailand

Intervention Type BEHAVIORAL

Eligibility Criteria

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Inclusion Criteria

* any individual residing in one of the 16 villages selected in the Khon Kaen province of Thailand, aged 20 and older

Exclusion Criteria

* any individual 19 years or younger
* any individual not residing in one of the 16 pre-selected villages in the Khon Kaen province of Thailand
Minimum Eligible Age

20 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Khon Kaen University

OTHER

Sponsor Role collaborator

Global Alliance for Chronic Diseases (GACD)

OTHER

Sponsor Role collaborator

Canadian Institutes of Health Research (CIHR)

OTHER_GOV

Sponsor Role collaborator

McMaster University

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Gina Agarwal, MBBS, PhD

Role: PRINCIPAL_INVESTIGATOR

McMaster University

Pattapong Kessomboon, MD, PhD

Role: PRINCIPAL_INVESTIGATOR

Khon Kaen University

Locations

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Khon Kaen University

Phu Wiang, Changwat Khon Kaen, Thailand

Site Status RECRUITING

Countries

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Thailand

Central Contacts

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Ricardo Angeles, MD, MPH, MHPEd, PhD

Role: CONTACT

905-515-2100 ext. 21203

Other Identifiers

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13955

Identifier Type: OTHER

Identifier Source: secondary_id

0609004105

Identifier Type: -

Identifier Source: org_study_id

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