Evaluation of an Adapted Formula on Atopic Dermatitis.

NCT ID: NCT05318300

Last Updated: 2023-12-08

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

ACTIVE_NOT_RECRUITING

Clinical Phase

NA

Total Enrollment

126 participants

Study Classification

INTERVENTIONAL

Study Start Date

2022-05-24

Study Completion Date

2024-04-30

Brief Summary

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The aim of this study is to show the efficiency of a new infant formula containing fiber on the management of moderate to severe atopic dermatitis.

Detailed Description

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The study is double blind randomized where the new formula is compared to a placebo during 3 months followed by a period of 3 months optional. During this period of time, all infant include in the study will be fed with the study formula.

Conditions

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Atopic Dermatitis

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

QUADRUPLE

Participants Caregivers Investigators Outcome Assessors

Study Groups

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Tested formula LP-2018

infant formula containing fibers

Group Type EXPERIMENTAL

tested formula with fiber

Intervention Type DIETARY_SUPPLEMENT

formula containing fibers

Placebo formula CT-2018

infant formula without fibers

Group Type PLACEBO_COMPARATOR

Control

Intervention Type DIETARY_SUPPLEMENT

formula without fiber

Interventions

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tested formula with fiber

formula containing fibers

Intervention Type DIETARY_SUPPLEMENT

Control

formula without fiber

Intervention Type DIETARY_SUPPLEMENT

Eligibility Criteria

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Inclusion Criteria

* Aged below 18 month
* Having an atopic dermatitis diagnosed according to the United Kingdom Working Party - Having an Eczema Area Severity Index (EASI) between 7.1 and 50.0
* Whose parents gave their informed consent

Exclusion Criteria

* systemic corticotherapy
* antihistamine
* use of dermocorticoide and/or antibiotics within 15 days
* symptoms of cutaneous infection
* Past anaphylactic shock
* cow's milk, soya or fish allergy
* Exclusive or predominant breast feediing (more than one feeding/day)
* Consumption of less than 500 ml per day
* Participation to another trial.
Minimum Eligible Age

1 Month

Maximum Eligible Age

18 Months

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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United Pharmaceuticals

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Fabienne Cahn-Sellem

Role: PRINCIPAL_INVESTIGATOR

Private Practice

Sebastien Barbarot

Role: STUDY_CHAIR

Hotel Dieu Hospital, Nantes, France

Elena Bradatan

Role: PRINCIPAL_INVESTIGATOR

Private Practice

Locations

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Center_13

Namur, , Belgium

Site Status

Center_14

Thuin, , Belgium

Site Status

Center_05

Nice, , France

Site Status

Countries

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Belgium France

Other Identifiers

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UP2018-EFITOP

Identifier Type: -

Identifier Source: org_study_id