A New Intelligent Stocking for Quantification of Edema in the Lower Limbs

NCT ID: NCT05310435

Last Updated: 2025-06-04

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

TERMINATED

Total Enrollment

6 participants

Study Classification

OBSERVATIONAL

Study Start Date

2018-08-01

Study Completion Date

2025-01-30

Brief Summary

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The purpose of the study is to evaluate a prototype of an intelligent stocking (Edema Stocking Device \[ESD\]), consisting of two stretch sensitive sensors, as a new method for continuously lower leg volume monitoring. The study is a scientific evaluation of the ESD compared with water displacement volumetry and tape measure.

Detailed Description

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Background:

Balance of body fluids is strictly regulated within a narrow range and is controlled by water movement between the interstitial compartment and the capillaries. An unnatural balance between the two compartments can be seen in several diseases, leading to a net filtration out of the vascular space, resulting in the formation of edema. Monitoring of edema formation represents a unique way of evaluating the degree of the underlying disease and effect of treatment. Numerous different methods can be used to quantify leg volume. However, no current method provides continuous quantitative assessment. The feasibility of continuous lower leg measuring using an intelligent stocking was hypothesized.

The aim of the study was to evaluate the Edema Stocking device (ESD) as a tool for continuous quantification of edema compared with water displacement volumetry (WDV) and tape measure.

Materials and methods:

Study design: Non-randomized equivalence study. Experimental comparison study of new method compared to golden standard.

Conditions

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Edema Leg

Study Design

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Observational Model Type

OTHER

Study Time Perspective

PROSPECTIVE

Study Groups

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Pregnant women with lower leg edema

Pregnant women with clinical lower leg edema measured two times with Edema Stocking device, two times with water displacement volumetry and two with tape measure each day for three days.

Single volume measurement with ESD

Intervention Type DEVICE

Single volume measurement with Edema Stocking device

Single volume measurement with WDV

Intervention Type DEVICE

Single volume measurement with water displacement volumetry method

Single circumference measurement with tape measure

Intervention Type DEVICE

Single circumference measurement with tape measure

Continuous volume measurement with ESD

Intervention Type DEVICE

Continuous volume measurement with Edema Stocking device

Interventions

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Single volume measurement with ESD

Single volume measurement with Edema Stocking device

Intervention Type DEVICE

Single volume measurement with WDV

Single volume measurement with water displacement volumetry method

Intervention Type DEVICE

Single circumference measurement with tape measure

Single circumference measurement with tape measure

Intervention Type DEVICE

Continuous volume measurement with ESD

Continuous volume measurement with Edema Stocking device

Intervention Type DEVICE

Eligibility Criteria

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Inclusion Criteria

* Edema of the lower legs.
* Between 20-18 years.
* Identified at Department of Gynaecology and Obstetrics, Aarhus University Hospital, Denmark.

Exclusion Criteria

* Length of lower leg of more than 34,0 cm (measured from floor to knee).
Minimum Eligible Age

20 Years

Maximum Eligible Age

40 Years

Eligible Sex

FEMALE

Accepts Healthy Volunteers

No

Sponsors

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Ohmatex ApS

UNKNOWN

Sponsor Role collaborator

Aarhus University Hospital

OTHER

Sponsor Role collaborator

University of Aarhus

OTHER

Sponsor Role lead

Responsible Party

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Alexander Emil Kaspersen

Project manager

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Olav B Petersen, MD, PhD

Role: STUDY_DIRECTOR

Aarhus University Hospital

Locations

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Department og Gynaecology and Obstetrics, Aarhus University Hospital

Aarhus, , Denmark

Site Status

Countries

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Denmark

Provided Documents

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Document Type: Informed Consent Form

View Document

Other Identifiers

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2017084027

Identifier Type: OTHER

Identifier Source: secondary_id

1-10-72-143-17

Identifier Type: -

Identifier Source: org_study_id

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