Stem Cells and Stromal Vascular Fraction for Temporomandibular Joint Disease
NCT ID: NCT05305833
Last Updated: 2022-03-31
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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UNKNOWN
PHASE1/PHASE2
20 participants
INTERVENTIONAL
2021-10-01
2023-12-01
Brief Summary
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Detailed Description
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Conditions
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Study Design
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RANDOMIZED
PARALLEL
TREATMENT
SINGLE
Study Groups
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umbilical cord derived mesenchymal stem cells transplantation group
taking umbilical cord derived mesenchymal stem cells
Stem Cells
ATMP
stromal vascular fraction cells application group
taking stromal vascular fraction cells
Stem Cells
ATMP
Interventions
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Stem Cells
ATMP
Eligibility Criteria
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Inclusion Criteria
* History of pain and joint noises for at least 3 months
* Must have more than VAS 5 TMJ pain
* must have internal derangement of TMJ
* Limited mouth opening
* Magnetic resonance imaging evidence of effusion or degeneration
* Already treated with conservative methods (occlusal splint,pharmacological and/or physio-kinesio therapy) without satisfactory benefit.
Exclusion Criteria
* Immunosupressed patients
* Previous TMJ traumas and fractures
* Previous TMJ surgeries
* TMJ ankylosis
18 Years
65 Years
ALL
No
Sponsors
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TC Erciyes University
OTHER
Responsible Party
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Zeynep Burcin GONEN
Associate Professor
Principal Investigators
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Zeynep B Gonen, DDS,PHD
Role: PRINCIPAL_INVESTIGATOR
Assoc.Prof
Locations
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Erciyes University
Kayseri, , Turkey (Türkiye)
Countries
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Central Contacts
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Genkok center
Role: CONTACT
Facility Contacts
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Genkok Center
Role: primary
Other Identifiers
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2021/584
Identifier Type: -
Identifier Source: org_study_id