Trial Outcomes & Findings for Patient Priorities Care for Hispanics With Dementia (NCT NCT05303194)

Last Updated: 2025-08-08

Results Overview

Participants were asked to grade how valuable they thought the PPC approach was. We report the percentage of participants who responded "valuable" or "very valuable" on a scale from 1 to 5 with 1 representing "not valuable" and 5 representing "very valuable".

Recruitment status

COMPLETED

Study phase

Target enrollment

21 participants

Primary outcome timeframe

On average one month after baseline

Results posted on

2025-08-08

Participant Flow

Participants were recruited based on Hispanic ethnicity from a UTMB Galveston outpatient clinic, participants without cognitive impairment, and with cognitive impairment. The first participant was enrolled on May 31st, 2022 and the last participant was enrolled in January 2024.

The number of participants started/completed represents the number of individual participants.

Participant milestones

Participant milestones
Measure	Patient Priorities Care (PPC) Adaptation Participants are Hispanic patients with multiple chronic conditions (MCC) and no dementia. Participants went through two parts of the Patient Priorities Care (PPC) approach: 1) Priority Setting; and 2) Care Alignment	PPC Feasibility Testing Participants are Hispanics participants diagnosed mild cognitive impairment or dementia and multiple chronic conditions (MCC) were recruited. They went through two parts of the Patient Priorities Care (PPC) approach: 1) Priority Setting; and 2) Care Alignment
Overall Study STARTED	5	16
Overall Study COMPLETED	4	14
Overall Study NOT COMPLETED	1	2

Reasons for withdrawal

Reasons for withdrawal
Measure	Patient Priorities Care (PPC) Adaptation Participants are Hispanic patients with multiple chronic conditions (MCC) and no dementia. Participants went through two parts of the Patient Priorities Care (PPC) approach: 1) Priority Setting; and 2) Care Alignment	PPC Feasibility Testing Participants are Hispanics participants diagnosed mild cognitive impairment or dementia and multiple chronic conditions (MCC) were recruited. They went through two parts of the Patient Priorities Care (PPC) approach: 1) Priority Setting; and 2) Care Alignment
Overall Study Lost to Follow-up	1	1
Overall Study Withdrawal by Subject	0	1

Baseline Characteristics

Patient Priorities Care for Hispanics With Dementia

Baseline characteristics by cohort

Baseline characteristics by cohort
Measure	PPC Adaptation n=5 Participants Five participants with multiple chronic conditions	PPC Feasibility n=16 Participants Sixteen with multiple chronic conditions and cognitive impairment	Total n=21 Participants Total of all reporting groups
Age, Categorical <=18 years	0 Participants n=5 Participants	0 Participants n=7 Participants	0 Participants n=5 Participants
Age, Categorical Between 18 and 65 years	0 Participants n=5 Participants	0 Participants n=7 Participants	0 Participants n=5 Participants
Age, Categorical >=65 years	5 Participants n=5 Participants	16 Participants n=7 Participants	21 Participants n=5 Participants
Sex: Female, Male Female	2 Participants n=5 Participants	5 Participants n=7 Participants	7 Participants n=5 Participants
Sex: Female, Male Male	3 Participants n=5 Participants	11 Participants n=7 Participants	14 Participants n=5 Participants
Ethnicity (NIH/OMB) Hispanic or Latino	5 Participants n=5 Participants	16 Participants n=7 Participants	21 Participants n=5 Participants
Ethnicity (NIH/OMB) Not Hispanic or Latino	0 Participants n=5 Participants	0 Participants n=7 Participants	0 Participants n=5 Participants
Ethnicity (NIH/OMB) Unknown or Not Reported	0 Participants n=5 Participants	0 Participants n=7 Participants	0 Participants n=5 Participants
Race (NIH/OMB) American Indian or Alaska Native	0 Participants n=5 Participants	0 Participants n=7 Participants	0 Participants n=5 Participants
Race (NIH/OMB) Asian	0 Participants n=5 Participants	0 Participants n=7 Participants	0 Participants n=5 Participants
Race (NIH/OMB) Native Hawaiian or Other Pacific Islander	0 Participants n=5 Participants	0 Participants n=7 Participants	0 Participants n=5 Participants
Race (NIH/OMB) Black or African American	0 Participants n=5 Participants	0 Participants n=7 Participants	0 Participants n=5 Participants
Race (NIH/OMB) White	0 Participants n=5 Participants	0 Participants n=7 Participants	0 Participants n=5 Participants
Race (NIH/OMB) More than one race	0 Participants n=5 Participants	0 Participants n=7 Participants	0 Participants n=5 Participants
Race (NIH/OMB) Unknown or Not Reported	5 Participants n=5 Participants	16 Participants n=7 Participants	21 Participants n=5 Participants
Cognitive impairment	0 Participants n=5 Participants	16 Participants n=7 Participants	16 Participants n=5 Participants
Multiple Chronic Conditions	5 Participants n=5 Participants	16 Participants n=7 Participants	21 Participants n=5 Participants

PRIMARY outcome

Timeframe: On average one month after baseline

Population: One participant from the Adaptation arm was lost to follow-up after the initial visit. In the Feasibility testing group one participant withdrew after consenting and before the first visit, and one participant was lost to follow-up after completing the intervention. Only patients are included in the analysis, caregivers are not active participants in the study.

Outcome measures

Outcome measures
Measure	Patient Priorities Care (PPC) Adaptation n=4 Participants Participants are Hispanic patients with multiple chronic conditions (MCC) and no dementia. Participants went through two parts of the Patient Priorities Care (PPC) approach: 1) Priority Setting; and 2) Care Alignment	PPC Feasibility Testing n=14 Participants Participants are Hispanics participants diagnosed mild cognitive impairment or dementia and multiple chronic conditions (MCC) were recruited. They went through two parts of the Patient Priorities Care (PPC) approach: 1) Priority Setting; and 2) Care Alignment
Self-reported Perceived Value of Patient Priorities Care (PPC) Approach	75 percentage of participants	85.7 percentage of participants

SECONDARY outcome

Timeframe: Approximately one month after baseline

Population: One participant was lost to follow-up after baseline and did not complete the study in the Adaptation group. In the feasibility group one participants withdrew before the PPC approach could be completed.

Dichotomous variable (yes vs no). Review of medical records to identify changes in care based on priorities identified by participants as a result of the Patient Priorities Care (PPC) approach. All medical charts were reviewed for language indicating that the primary care providers used the patient priorities to align the care provided to the patient. The default sentence provided to the providers was "Based on the patient's specific priorities, including outcome goals and care preferences, we decided to..." If information resembling this wording was found, then Care alignment was marked as positive. Otherwise, it was marked as negative.

Outcome measures

Outcome measures
Measure	Patient Priorities Care (PPC) Adaptation n=5 Participants Participants are Hispanic patients with multiple chronic conditions (MCC) and no dementia. Participants went through two parts of the Patient Priorities Care (PPC) approach: 1) Priority Setting; and 2) Care Alignment	PPC Feasibility Testing n=16 Participants Participants are Hispanics participants diagnosed mild cognitive impairment or dementia and multiple chronic conditions (MCC) were recruited. They went through two parts of the Patient Priorities Care (PPC) approach: 1) Priority Setting; and 2) Care Alignment
Number of Participants With Documented Changes in the Electronic Health Record That Indicate Care Alignment Was Done	4 Participants	15 Participants

Adverse Events

Patient Priorities Care (PPC) Adaptation

Serious events: 0 serious events

Other events: 0 other events

Deaths: 0 deaths

PPC Feasibility Testing

Serious events: 0 serious events

Other events: 0 other events

Deaths: 0 deaths

Serious adverse events

Adverse event data not reported

Other adverse events

Adverse event data not reported

Additional Information

Rafael Samper-Ternent

The University of Texas Medical Branch

Phone: 8322057994

Email: [email protected]

Results disclosure agreements

Principal investigator is a sponsor employee
Publication restrictions are in place