A Project to Study Probiotic Beauty Products on Skin Improvement

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.

Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

20 participants

Study Classification

INTERVENTIONAL

Study Start Date

2020-05-18

Study Completion Date

2020-08-15

Brief Summary

Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.

The aim of the study was to use probiotic beauty products for 4 weeks and evaluate the impact of products on healthy skin.

Related Clinical Trials

Explore similar clinical trials based on study characteristics and research focus.

Efficacy Evaluation of the Probiotics Containing Skincare Products on Skin

NCT03350893

Skin Problems

COMPLETED NA

The Safety and Efficacy Evaluation of Hair Products Containing Probiotics

NCT04566549

Skin Problems

COMPLETED PHASE2

The Efficacy Evaluation of TCI604 Probiotic on Intestinal Function Improvement

NCT07135362

Constipation Intestinal Functional Disorder

RECRUITING NA

Effects of Probiotics on Improving the Gastrointestinal Function and Intestinal Bacterial Flora

NCT01428999

Gastrointestinal Function Intestinal Bacteria Flora

UNKNOWN NA

Probiotics Regulates Skin Care in Children

NCT05005611

Skin Care Probiotics Children

UNKNOWN NA

Detailed Description

Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.

Twenty subjects were recruited and informed to apply the lotion gel twice per day (3\~5 mg/cm2 once) for 4 weeks. Two kinds of facial lotiongels, "A" gel and "B" gel, were provided to every subject. The "A" gel (TAC/Collagen lotiongel) was applied on subjects' right face and the "B" gel (placebo lotion) on their left face (formula showed as Table S2). Ordinary cosmetics usage was permitted but any change of usage was not allowed during the intervention. Outdoor activities (sun exposure) and the usage of sunscreen lotion were not limited in this study. Every subject was required to inspect his/her skin condition on week 0 and 4. Before inspection, the face was washed with water and waited for 30 min in an air-conditioned room (25°C, humility 55 ± 5%). Among these 20 subjects, eight of them had severe acne with at least two acne lesions on each side of face when participating this trial. They were instructed for more visits to evaluate the symptom of acne on week 1 and 2.

Skin hydration (Corneometer CM825, Courage + Khazaka Electroni, Germany), sebum (Callegari 1930, Italy), and inflammation detection (Chroma Meter MM-500, Minolta, Japan) of upper cheek were measured in every subject. The improvement in inflammation was positively correlated with a decrease of a\* value or an increase of L\* value. VISIA® Complexion Analysis (VISIA® Complexion Analysis, U.S.A.) was also employed to measure the skin inflammation, porphyrins numbers and brown spot numbers of whole face. The result was presented as the mean value and the relative percentage (%) to the baseline.

Conditions

See the medical conditions and disease areas that this research is targeting or investigating.

Skin Diseases

Study Design

Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.

Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

SINGLE

Investigators

Study Groups

Review each arm or cohort in the study, along with the interventions and objectives associated with them.

"A" gel (TAC/Collagen gel)

The "A" gel (TAC/Collagen gel) was applied on subjects' right face

Group Type EXPERIMENTAL

TAC/Collagen gel

Intervention Type DIETARY_SUPPLEMENT

Apply it twice per day for 4 weeks

"B" gel (placebo lotion)

the "B" gel (placebo lotion) on their left face

Group Type PLACEBO_COMPARATOR

placebo lotion

Intervention Type DIETARY_SUPPLEMENT

Apply it twice per day for 4 weeks

Interventions

Learn about the drugs, procedures, or behavioral strategies being tested and how they are applied within this trial.

TAC/Collagen gel

Apply it twice per day for 4 weeks

Intervention Type DIETARY_SUPPLEMENT

placebo lotion

Apply it twice per day for 4 weeks

Intervention Type DIETARY_SUPPLEMENT

Eligibility Criteria

Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.

Inclusion Criteria

Healthy volunteers aged above 20 years old

Exclusion Criteria

1. Subject with diseases of the skin, heart, liver, kidney, endocrine and other organs and patients with mental illness (according to medical history).
2. Subjects who have known cosmetic, drug or food allergies, difficulty in digestive tract absorption or disorder.
3. Female who is pregnant or nursing or planning to become pregnant during the course of the study.
4. Received facial laser therapy, chemical peeling or UV overexposure in the past 4 weeks.
5. Involuntary subject
6. People who is taking chronic disease medication

Minimum Eligible Age

20 Years

Maximum Eligible Age

65 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes