FDG (Fluorodeoxyglucose) Findings After COVID-19 Vaccination

NCT ID: NCT05270967

Last Updated: 2022-03-08

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

129 participants

Study Classification

OBSERVATIONAL

Study Start Date

2021-07-29

Study Completion Date

2022-01-10

Brief Summary

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It is important to evaluate the vaccine-related metabolic changes on FDG PET/CT to avoid confusing results. The investigators aimed to assess the frequency and intensity of regional and systemic metabolic PET/CT changes of patients who received the mRNA-based COVID-19 vaccine (BNT162b2-Pfizer/BioNTech) and to analyze possible factors affecting these changes.

Detailed Description

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Conditions

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Vaccine Reaction Oncology

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Interventions

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F-18 FDG PET/CT imaging

Oncological imaging

Intervention Type DIAGNOSTIC_TEST

Pfizer/biontech mRNA vaccine

COVID-19 vaccine

Intervention Type BIOLOGICAL

Eligibility Criteria

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Inclusion Criteria

* patients referred for post-vaccination FDG PET/CT imaging
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Kocaeli University

OTHER

Sponsor Role lead

Responsible Party

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Serkan Isgoren

associate professor of nuclear medicine

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Serkan Isgoren, Ass prof

Role: STUDY_CHAIR

Kocaeli University School of Medicine

Locations

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Kocaeli University School of Medicine Dep. of Nuclear Medicine

Kocaeli, , Turkey (Türkiye)

Site Status

Countries

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Turkey (Türkiye)

References

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Cohen D, Krauthammer SH, Wolf I, Even-Sapir E. Hypermetabolic lymphadenopathy following administration of BNT162b2 mRNA Covid-19 vaccine: incidence assessed by [18F]FDG PET-CT and relevance to study interpretation. Eur J Nucl Med Mol Imaging. 2021 Jun;48(6):1854-1863. doi: 10.1007/s00259-021-05314-2. Epub 2021 Mar 27.

Reference Type RESULT
PMID: 33774684 (View on PubMed)

Other Identifiers

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GOKAEK-2021/14.18

Identifier Type: -

Identifier Source: org_study_id

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