Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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UNKNOWN
NA
15 participants
INTERVENTIONAL
2022-02-01
2023-07-31
Brief Summary
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Detailed Description
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Conditions
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Study Design
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NA
SINGLE_GROUP
TREATMENT
NONE
Study Groups
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Anti-reflux mucosal ablation
This technique creates an anti-reflux mechanism by performing mucosal ablation at the gastric cardia and inducing cicatrisation, and thereby rebuilds the flap valve at the gastric cardia
Anti-reflux mucosal ablation
Mucosal ablation is planned around the cardia on the gastric side in a butterfly shape. Submucosal layer is raised by injecting saline with indigo carmine dye. Mucosal ablation is performed using the triangle-tip knife in spray coagulation mode.
Interventions
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Anti-reflux mucosal ablation
Mucosal ablation is planned around the cardia on the gastric side in a butterfly shape. Submucosal layer is raised by injecting saline with indigo carmine dye. Mucosal ablation is performed using the triangle-tip knife in spray coagulation mode.
Other Intervention Names
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Eligibility Criteria
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Inclusion Criteria
* Pathological esophageal acid exposure, defined by DeMeester score \>14.7 or acid exposure time (AET) \>4.2% on pH study
Exclusion Criteria
* Sliding hiatal hernia \>3cm
* Narrow gastric sleeve that precludes retroflexion of scope
* Gastric sleeve stricture
* Malignancy
* Pregnancy
* Patients not fit for general anesthesia
* Other cases deemed by the examining physician as unsuitable for safe treatment
* Refusal to participate
18 Years
65 Years
ALL
No
Sponsors
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Chinese University of Hong Kong
OTHER
Responsible Party
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Stephen K.K. Ng
Principal Investigator
Locations
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Chinese University of Hong Kong
Hong Kong, , Hong Kong
Countries
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Central Contacts
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Facility Contacts
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Stephen KK Ng, FRCSEd(Gen)
Role: primary
Man Yee Yung
Role: backup
Other Identifiers
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CRE-2021.553
Identifier Type: -
Identifier Source: org_study_id