Microchimeric Cell Tranfer From Mother to Child - Pilo Study

NCT ID: NCT05250219

Last Updated: 2022-02-22

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.

Recruitment Status

UNKNOWN

Total Enrollment

80 participants

Study Classification

OBSERVATIONAL

Study Start Date

2021-09-01

Study Completion Date

2022-12-31

Brief Summary

Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.

Microchimeric cells are known to be transferred from mother to child through the placenta. However it has been postulated that they could also be transferred through breastfeeding.

This study is designed to analyse lymphoid and digestive tract tissues (tonsils and appendixes) in male infants (or young adults) to research microchimeric female cells and try to correlate the frequency and localisation of said cells to the breastfeeding status during early infancy

Detailed Description

Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.

Conditions

See the medical conditions and disease areas that this research is targeting or investigating.

Breastfeeding

Study Design

Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.

Observational Model Type

COHORT

Study Time Perspective

RETROSPECTIVE

Study Groups

Review each arm or cohort in the study, along with the interventions and objectives associated with them.

patients for tonsils

40 patients for tonsils

No interventions assigned to this group

patients for appendixes

40 patients for appendixes)

No interventions assigned to this group

Eligibility Criteria

Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.

Inclusion Criteria

* age 1-16 years (at the time of surgery)
* male
* known breastfeeding status in infancy

Exclusion Criteria

* premature birth (before 37 weeks)
* history of blood transfusion
* history of bone marrow transplant
* history of organ transplant
* patient known to have a twin
* known gonosomal
Minimum Eligible Age

1 Year

Maximum Eligible Age

16 Years

Eligible Sex

MALE

Accepts Healthy Volunteers

No

Sponsors

Meet the organizations funding or collaborating on the study and learn about their roles.

University Hospital, Montpellier

OTHER

Sponsor Role lead

Responsible Party

Identify the individual or organization who holds primary responsibility for the study information submitted to regulators.

Responsibility Role SPONSOR

Principal Investigators

Learn about the lead researchers overseeing the trial and their institutional affiliations.

Boris DMITRENKO

Role: STUDY_DIRECTOR

UH MONTPELLIER - FRANCE

Locations

Explore where the study is taking place and check the recruitment status at each participating site.

Uh Montpellier

Montpellier, , France

Site Status RECRUITING

Countries

Review the countries where the study has at least one active or historical site.

France

Central Contacts

Reach out to these primary contacts for questions about participation or study logistics.

Franck PELLESTOR, MD PHD

Role: CONTACT

06.29.04.83.18 ext. 33

Boris DMITRENKO, interne

Role: CONTACT

06.29.04.83.18 ext. 33

Facility Contacts

Find local site contact details for specific facilities participating in the trial.

Boris DMITRENKO

Role: primary

06.29.04.83.18 ext. 33

Franck PELLESTOR

Role: backup

Other Identifiers

Review additional registry numbers or institutional identifiers associated with this trial.

RECHMPL21_0724

Identifier Type: -

Identifier Source: org_study_id

More Related Trials

Additional clinical trials that may be relevant based on similarity analysis.

Breastfeeding and Gut Health
NCT04195425 RECRUITING
Fat Globules in Breast Milk
NCT01034722 UNKNOWN
Social Transfers for Exclusive Breastfeeding
NCT05665049 ACTIVE_NOT_RECRUITING NA
Puncture Breast Abscess
NCT03730467 WITHDRAWN