Correlation Between Functional Capacity and Functional Capability in Duchenne Muscular Dystrophy

NCT ID: NCT05249361

Last Updated: 2023-11-29

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Total Enrollment

48 participants

Study Classification

OBSERVATIONAL

Study Start Date

2023-05-01

Study Completion Date

2025-10-01

Brief Summary

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This study investigates the correlation between assessments measuring functional capacity and functional capability in patients with Duchenne muscular dystrophy.

Detailed Description

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This study is a prospective single-arm observational study, with a total of two visits for one year follow-up.

Conditions

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Duchenne Muscular Dystrophy

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

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Duchenne Muscular Dystrophy

Children aged 5 to 18 years with Duchenne muscular dystrophy

no intervention

Intervention Type OTHER

no intervention

Interventions

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no intervention

no intervention

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

1. Children aged 5 to 18 years diagnosed with Duchenne muscular dystrophy through genetic testing
2. Children who understand the contents of this research and can properly conduct the research

Exclusion Criteria

1. Requiring daytime ventilator assistance or using invasive mechanical ventilation through tracheostomy (Non-invasive mechanical ventilation such as positive pressure ventilation at night is allowed)
2. History of peripheral nerve damage
3. History of major surgery within 12 weeks or if major surgery is expected during the test period
4. History of central nervous system disorders (eg, cerebral infarction, spinal cord injury)
5. Having difficulties in conducting this study due to cognitive decline.
Minimum Eligible Age

5 Years

Maximum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Samsung Medical Center

OTHER

Sponsor Role lead

Responsible Party

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Jeong Yi Kwon

Professor

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Jeong-yi Kwon, MD,Ph.D

Role: PRINCIPAL_INVESTIGATOR

Samsung Medical Center

Locations

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Samsung Medical Center

Seoul, , South Korea

Site Status RECRUITING

Samsung Medical Center

Seoul, , South Korea

Site Status RECRUITING

Countries

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South Korea

Central Contacts

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Yumi Choe

Role: CONTACT

82-010-3173-2671

Facility Contacts

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Yumi Choe

Role: primary

+8231732671

JEONG-YI KWON, MD, PHD

Role: primary

+8210-4591-1039

References

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Im YJ, Choe Y, Lee J, Lee J, Do JG, Kwon JY. Quantitative Muscle Ultrasound: A Non-Invasive Biomarker for Monitoring Duchenne Muscular Dystrophy. Muscle Nerve. 2025 Oct;72(4):606-615. doi: 10.1002/mus.28469. Epub 2025 Jul 16.

Reference Type DERIVED
PMID: 40671379 (View on PubMed)

Other Identifiers

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2022-05-136

Identifier Type: -

Identifier Source: org_study_id