Immediate Versus Early (24-hours) Urinary Catheter Removal After Elective Minimally Invasive Colonic Resection

NCT ID: NCT05249192

Last Updated: 2024-11-29

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.

Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

216 participants

Study Classification

INTERVENTIONAL

Study Start Date

2022-02-15

Study Completion Date

2024-11-26

Brief Summary

Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.

The primary aim of this study is to compare the rate of acute urinary retention (AUR) after immediate compared to early (24-hours) removal of urinary catheter (UC) in patients undergoing minimally invasive colorectal resection. The study hypothesis is that immediate UC removal is non-inferior to 24-hours UC removal in terms of AUR rate.

The secondary outcomes focus on goals that could be positively impacted by the immediate removal of the UC at the end of the surgery. In particular, the rate of urinary tract infections, perception of pain, time-to-return of bowel and physical functions, postoperative complications and postoperative length of stay will all be measured.

Detailed Description

Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.

Conditions

See the medical conditions and disease areas that this research is targeting or investigating.

Surgical Complication Colonic Disease Postoperative Complications Urinary Retention Postoperative Urinary Tract Infections

Study Design

Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.

Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

prospective, randomized, controlled, two-arm, multi-center trial
Primary Study Purpose

PREVENTION

Blinding Strategy

DOUBLE

Participants Caregivers
patients and surgeons are blinded to group allocation until the end of surgical procedure

Study Groups

Review each arm or cohort in the study, along with the interventions and objectives associated with them.

Immediate UC removal

Urinary catheter removal immediately after the end of the surgical procedure before exiting the operating room.

Group Type EXPERIMENTAL

Immediate urinary catheter removal

Intervention Type DEVICE

Urinary catheter removal immediately after the end of the surgical procedure before exiting the operating room.

Early UC removal

Urinary catheter removal on first postoperative day (6 a.m.) as per standard protocol

Group Type ACTIVE_COMPARATOR

Early urinary catheter removal

Intervention Type DEVICE

urinary catheter removal on the first postoperative day (6 a.m)

Interventions

Learn about the drugs, procedures, or behavioral strategies being tested and how they are applied within this trial.

Immediate urinary catheter removal

Urinary catheter removal immediately after the end of the surgical procedure before exiting the operating room.

Intervention Type DEVICE

Early urinary catheter removal

urinary catheter removal on the first postoperative day (6 a.m)

Intervention Type DEVICE

Eligibility Criteria

Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.

Inclusion Criteria

1. Age between 18 years and 80 years old
2. Patients scheduled to undergo minimally invasive resection of the colon under general anesthesia
3. Willingness to participate
4. Compliance to study purpose
5. Written informed consent

Exclusion Criteria

1. Need for an anastomosis below the anterior peritoneal reflection
2. Need for a major resection other than colorectal
3. Need for post-operative intensive care monitoring or intensive care unit (ICU) stay
4. Anesthesia time longer than 300 minutes
5. Presence of chronic indwelling UC
6. Presence of an entero-vesical fistula
7. Need for ureteral stent placement, bladder resection or repair
8. A previous and unsolved history of AUR or overt voiding dysfunction
Minimum Eligible Age

18 Years

Maximum Eligible Age

80 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

Meet the organizations funding or collaborating on the study and learn about their roles.

Faenza Hospital

UNKNOWN

Sponsor Role collaborator

Ravenna Hospital

UNKNOWN

Sponsor Role collaborator

Humanitas Research Hospital IRCCS, Rozzano-Milan

OTHER

Sponsor Role collaborator

Humanitas University

UNKNOWN

Sponsor Role collaborator

Universita di Verona

OTHER

Sponsor Role collaborator

Azienda Ospedaliera Universitaria Integrata Verona

OTHER

Sponsor Role lead

Responsible Party

Identify the individual or organization who holds primary responsibility for the study information submitted to regulators.

Responsibility Role SPONSOR

Principal Investigators

Learn about the lead researchers overseeing the trial and their institutional affiliations.

Corrado Pedrazzani, Professor

Role: PRINCIPAL_INVESTIGATOR

Universita di Verona

Locations

Explore where the study is taking place and check the recruitment status at each participating site.

Division of General and Hepatobiliary Surgery

Verona, Italy, Italy

Site Status

Countries

Review the countries where the study has at least one active or historical site.

Italy

References

Explore related publications, articles, or registry entries linked to this study.

Pedrazzani C, Montroni I, Conti C, Turri G, Foppa C, Carvello M, Taffurelli G, Ugolini G, Spinelli A. Immediate versus early (24-hours) urinary catheter removal after elective minimally invasive colonic resection: study protocol for a randomized, multicenter, non-inferiority trial. Trials. 2022 Nov 22;23(1):956. doi: 10.1186/s13063-022-06894-6.

Reference Type DERIVED
PMID: 36414969 (View on PubMed)

Other Identifiers

Review additional registry numbers or institutional identifiers associated with this trial.

EURiCaRe

Identifier Type: -

Identifier Source: org_study_id