Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
NA
65 participants
INTERVENTIONAL
2022-01-10
2023-04-23
Brief Summary
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Magnetic resonance (MR), better known as magnetic resonance imaging (MRI), has been widely used in clinical practice as a non-invasive imaging technique. Importantly, in addition to producing anatomical images, an MR scanner also offers the possibility to measure the concentrations of a number of metabolic products. This is done through a technique known as magnetic resonance spectroscopy (MRS).
This research project asks the following questions:
* Can a diet containing carbohydrates with a low glycemic index achieve the same adaptations in basic endurance/fat metabolism as a high fat, low carbohydrate (ketogenic) diet?
* Does a high-fat, low-carbohydrate diet, compared with a high-carbohydrate diet, prevent improvements in performance in the submaximal and maximal range?
* What is the effect of diets with different carbohydrate content and variable glycemic index on endurance performance in a half marathon and a time trial?
* How do the diets with different carbohydrate content and variable glycaemic index affect the energy and glycogen stores in the muscles?
In active recreational athletes, the objectives are: (1) to investigate the effects of different diets with variable carbohydrate content and glycaemic index on substrate metabolism, (2) to determine the effects of the different diets on energy stores using multinuclear dynamic magnetic resonance spectroscopy, and (3) to measure the effects of the different diets on endurance performance.
Detailed Description
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Conditions
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Study Design
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RANDOMIZED
PARALLEL
BASIC_SCIENCE
NONE
Study Groups
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Low GI
The subjects eat 55-60 E-% carbohydrates with ≥ 65 % from low glycaemic index carbohydrates per day, the other E-% are fats and proteins.
Training intervention
The training intervention will be a 10 week training plan for endurance runners. The plan consists of five sessions per week (three basic endurance sessions and two interval sessions)
Low Glycaemic Index
The subjects eat 55-60 E-% carbohydrates with ≥ 65 % from low glycaemic index carbohydrates per day, the other E-% are fats and proteins.
High GI
The subjects eat 55-60 E-% carbohydrates with ≥ 65 % from high glycaemic index carbohydrates per day, the other E-% are fats and proteins.
Training intervention
The training intervention will be a 10 week training plan for endurance runners. The plan consists of five sessions per week (three basic endurance sessions and two interval sessions)
High Glycaemic Index
The subjects eat 55-60 E-% carbohydrates with ≥ 65 % from high glycaemic index carbohydrates per day, the other E-% are fats and proteins.
Low Carb High Fat
The subjects eat ≥ 65 E-% fats and a maximum of 50 g carbohydrates per day.
Training intervention
The training intervention will be a 10 week training plan for endurance runners. The plan consists of five sessions per week (three basic endurance sessions and two interval sessions)
LCHF
The subjects eat ≥ 65 E-% fats and a maximum of 50 g carbohydrates per day.
Interventions
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Training intervention
The training intervention will be a 10 week training plan for endurance runners. The plan consists of five sessions per week (three basic endurance sessions and two interval sessions)
High Glycaemic Index
The subjects eat 55-60 E-% carbohydrates with ≥ 65 % from high glycaemic index carbohydrates per day, the other E-% are fats and proteins.
LCHF
The subjects eat ≥ 65 E-% fats and a maximum of 50 g carbohydrates per day.
Low Glycaemic Index
The subjects eat 55-60 E-% carbohydrates with ≥ 65 % from low glycaemic index carbohydrates per day, the other E-% are fats and proteins.
Eligibility Criteria
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Inclusion Criteria
* Age between 18 and 40 years
* Recreational active in leisure time (2-3x/week physical activity)
* Motivation for performance testing and structured training plan
* Interest in different diets
* no acute or chronic illnesses
Exclusion Criteria
* Age \<18 or \>40 years
* Taking medication that could influence the measurements or that is prohibited in training and/or competition according to the WADA (World Anti-Doping Agency) Code
* Competitive athlete with own training plan
* Experience with intervention diets
* Claustrophobia
* Cardiac pacemaker
* cochlear implant
* subcutaneous injection system
* Stents, metal implants, braces, piercings, tattoos
* Body weight of more than 180 kg or BMI of more than 37 kg/m2
18 Years
40 Years
MALE
Yes
Sponsors
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Medical University of Vienna
OTHER
University of Vienna
OTHER
Responsible Party
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Daniel König
Univ.-Prof. Dr. med., Head of Subunit Nutrition, Exercise and Health
Locations
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University of Vienna
Vienna, , Austria
Countries
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References
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Moitzi AM, Krssak M, Klepochova R, Triska C, Csapo R, Konig D. Effects of a 10-Week Exercise and Nutritional Intervention with Variable Dietary Carbohydrates and Glycaemic Indices on Substrate Metabolism, Glycogen Storage, and Endurance Performance in Men: A Randomized Controlled Trial. Sports Med Open. 2024 Apr 10;10(1):36. doi: 10.1186/s40798-024-00705-9.
Other Identifiers
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2105/2021
Identifier Type: -
Identifier Source: org_study_id