Double Pet Project : A Comparison Between 11C-Acetate and 11C-acetoacetate Heart and Kidney Uptake

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

10 participants

Study Classification

INTERVENTIONAL

Study Start Date

2022-03-14

Study Completion Date

2022-08-14

Brief Summary

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The objective of this study is to make a comparison between 11C-acetate and 11C-Acetoacetate heart and kidney metabolism

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Detailed Description

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Healthy people will have two positron emission tomography scan to perform. One, with a 11C-Acetate Tracer and the other with 11C-Acetoacetate. The results will allow to determine if both tracers are used in a similar way but the organs and see if the investigators can use the already validated analyse method for acetate to make acetoacetate analysis

Conditions

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Ketoses, Metabolic

Study Design

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Allocation Method

NA

Intervention Model

SEQUENTIAL

Participants will have to perform 2 scans one after the other

Primary Study Purpose

HEALTH_SERVICES_RESEARCH

Blinding Strategy

NONE

Study Groups

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Observational heart and kidney metabolism

Participants will have a PET scan with 11C-Acetate followed by a TEP Scan with 11C-Acetoacetate all in the same day.

Group Type OTHER

Observational heart and kidney on siemens TEP scan

Intervention Type RADIATION

Same as arm description

Interventions

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Observational heart and kidney on siemens TEP scan

Same as arm description

Intervention Type RADIATION

Eligibility Criteria

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Inclusion Criteria

* Aged between 18 and 55
* BMI between 18,5 and 28
* Healthy
* Normal value for blood pressure

Exclusion Criteria

* Taking drugs that could influence metabolism
* Diabetes or prediabetes
* Pregnancy or lactation
* Participation in a intensive sport program
* Being on a ketogenic diet
* Any clinical abnomally in prescreen blood sample

Minimum Eligible Age

18 Years

Maximum Eligible Age

55 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes