Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
NA
15 participants
INTERVENTIONAL
2019-11-01
2020-02-01
Brief Summary
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Though there are a lot of studies on physical training, there is little detail on hybrid training or electrical and voluntary contractions of the musculature. This study investigated the efficiency of hybrid training in biochemistry, ultrasound, and proinflammatory outcomes in middle-aged sedentary and obese women with NAFLD.
Detailed Description
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Conditions
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Study Design
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RANDOMIZED
PARALLEL
SUPPORTIVE_CARE
NONE
Study Groups
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Hybrid training
15 women for hybrid training.
hybrid training
The experimental group trained two to three sessions of 45 to 50 minutes a week with a recovery of 24 to 48 hours between each session to burn 500 kcal. The first three weeks held hybrid training with a metabolic program and the other three weeks held a strength training program.
Healthy lifestyle counseling
15 women for healthy lifestyle counseling
No interventions assigned to this group
Interventions
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hybrid training
The experimental group trained two to three sessions of 45 to 50 minutes a week with a recovery of 24 to 48 hours between each session to burn 500 kcal. The first three weeks held hybrid training with a metabolic program and the other three weeks held a strength training program.
Eligibility Criteria
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Inclusion Criteria
* BMI equal to or above 30 kg/m-2
* WHR equal or above 0.85 m
* Confirmed NAFLD, with grade 2 and 3
* Systolic blood pressure not less than 130 mm Hg and diastolic blood pressure not less than 85 mm Hg
* Increased AST and ALT
* Mean age 45-65 years
Exclusion Criteria
* History of depression in the last 6 months
* History of chronic or acute viral hepatitis
* Drug-related liver disease and chronic liver disease
* History of diabetes
* Uncontrolled hypertension
* Myocardial infarction
* Chronic kidney disease
* Hyperthyroidism or heart failure
* Those who have weight loss programs or medical contraindications for physical training
* Serious arterial hemorrhagic disorders
* Serious neurological diseases
* Advanced atherosclerosis
* Elevated fever
45 Years
65 Years
FEMALE
Yes
Sponsors
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Niloofar Zareie Mohammad Zadeh
UNKNOWN
University of Sistan and Baluchestan
OTHER
Responsible Party
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Mohammadreza Rezaeipour
Asst.Prof.Dr. of sports science
Principal Investigators
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Mohammadreza Rezaeipour, MD, PhD
Role: PRINCIPAL_INVESTIGATOR
University of Sistan and Baluchestan
Locations
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Mohammadreza Rezaeipour (MD, PhD)
Zahedan, Sistan and Baluchestan, Iran
Countries
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References
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Mohammadzadeh NZ, Rezaeipour M. "Hybrid exercise training improves liver steatosis and inflammation in a randomized trial of sedentary, obese women with non-alcoholic fatty liver disease". BMC Sports Sci Med Rehabil. 2025 Oct 24;17(1):308. doi: 10.1186/s13102-025-01349-2.
Other Identifiers
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no grant
Identifier Type: -
Identifier Source: org_study_id