Post-Marketing Surveillance (Special Use-results Surveillance on Long-term Use) With Sogroya®

NCT ID: NCT05230550

Last Updated: 2025-04-09

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

ENROLLING_BY_INVITATION

Total Enrollment

200 participants

Study Classification

OBSERVATIONAL

Study Start Date

2022-02-03

Study Completion Date

2026-12-31

Brief Summary

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Participants are invited to take part in this study because they have AGHD (only severe case). The purpose of this study is to assess long term safety and effectiveness of Sogroya® in patients with AGHD (only severe case) under normal clinical practice condition in Japan. Participants will get Sogroya® as prescribed by the study doctor. Participants will be in the study for about 2 to 5 years depending on when they take part in the study. Participants will be asked to fill in the quality of life questionnaires.

Detailed Description

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Conditions

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Adult Growth Hormone Deficiency

Study Design

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Observational Model Type

CASE_ONLY

Study Time Perspective

PROSPECTIVE

Study Groups

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Participants with AGHD (only severe case)

Participants will be treated with commercially available Sogroya® according to routine clinical practice at the discretion of the treating physician. The decision to treat a patient with Sogroya® has been made at the treating physician's discretion and independently from the decision to include the patient in this study.

Somapacitan

Intervention Type DRUG

Sogroya® therapy in participants with AGHD (only severe case) under normal clinical practice conditions

Interventions

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Somapacitan

Sogroya® therapy in participants with AGHD (only severe case) under normal clinical practice conditions

Intervention Type DRUG

Other Intervention Names

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Sogroya®

Eligibility Criteria

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Inclusion Criteria

1. Signed consent obtained before any study-related activities (study-related activities are any procedure related to recording of data according to the protocol)
2. The decision to initiate treatment with commercially available Sogroya® has been made by the patient/LAR and the treating physician before and independently from the decision to include the patient in this study.
3. Male or female, no age limitation
4. Diagnosis of AGHD (only severe case)
5. GH treatment naïve ("naïve patients") or "switched patients". "Naïve patients" are patients who are not exposed to any GH product to date or patients who were exposed to other GH product more than 180 days prior to registration. "Switched patients" are patients who is now treated by other GH product or patients who were exposed to other GH product within 180 days prior to registration.

Exclusion Criteria

1. Previous participation in this study. Participation is defined as having given informed consent in this study
2. Mental incapacity, unwillingness or language barriers precluding adequate understanding or cooperation
3. Patients with hypersensitivity to the active substance or to any of the excipients
4. Patients with malignant tumor
5. Female patients who are either pregnant or likely to be pregnant
Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Novo Nordisk A/S

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Clinical Transparency dept. 2834

Role: STUDY_DIRECTOR

Novo Nordisk A/S

Locations

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Ikeda Hospital, Diabetes Medicine

Amagasaki-shi, Hyogo, , Japan

Site Status

University of Yamanashi Hospital

Chuo-shi, Yamanashi-ken, , Japan

Site Status

Fukuoka University Chikushi Hospital_Endocrinology and Diabetes Mellitus

Fukuoka, , Japan

Site Status

Kurume University Hospital

Fukuoka, , Japan

Site Status

Fukuoka University Hospital

Fukuoka-shi, Fukuoka-ken, , Japan

Site Status

Kyushu University Hospital

Fukuoka-shi, Fukuoka, , Japan

Site Status

Gifu University Hospital

Gifu, , Japan

Site Status

Tsugaru General Hospital

Goshogawara-shi, Aomori-ken, , Japan

Site Status

Gunma University Hospital, Dept. of Endocrinology and Diabetes

Gunma, , Japan

Site Status

Hamamatsu University Hospital

Hamamatsu-shi, Shizuoka, , Japan

Site Status

Hirosaki University Hospital

Hirosaki-shi, Aomori-ken, , Japan

Site Status

Hyogo Prefectural Kakogawa Medical Center

Hyōgo, , Japan

Site Status

Takara Clinic

Iida-shi, Nagano-ken, , Japan

Site Status

Shimane Univ. HP, Dept of Endocrinology&Metabolism

Izumo, Shimane, , Japan

Site Status

Joetsu General Hospital

Joetsu-shi, Niigata-ken, , Japan

Site Status

Kagoshima Medical Center

Kagoshima-shi, Kagoshima-ken, , Japan

Site Status

Kagoshima University Hospital_Neurosurgery

Kagoshima-shi, Kagoshima, , Japan

Site Status

Yokohama Medical Center

Kanagawa, , Japan

Site Status

Kitasato University Hospital

Kanagawa, , Japan

Site Status

Nara Medical University Hospital_Kashihara-shi, Nara

Kashihara-shi, Nara, , Japan

Site Status

Nippon Medical School Musashikosugi Hospital_Neurological Surgery

Kawasaki-shi, Kanagawa, , Japan

Site Status

Kobe University Hospital

Kobe-shi, Hyogo, , Japan

Site Status

Konan Hospital

Kumamoto, , Japan

Site Status

Kumamoto University Hospital, Diabetes, Metabo and Endo

Kumamoto-shi, Kumamoto, , Japan

Site Status

Kyoto University Hospital

Kyoto-shi, Kyoto, , Japan

Site Status

Toranomon Hospital, Endocrinology and Metabolism

Minato-ku, Tokyo, , Japan

Site Status

University of Miyazaki Hospital

Miyazaki-shi, Miyazaki-ken, , Japan

Site Status

Aichi Medical University Hospital

Nagakute-shi, Aichi, , Japan

Site Status

Okamoto Internal Medicine and Pediatrics Clinic

Nara, , Japan

Site Status

Kurebayashi Diabetes Clinic

Nishinomiya-shi, Hyogo-ken, , Japan

Site Status

Okayama University Hospital_General Medicine

Okayama-shi, Okayama, , Japan

Site Status

Osaka Endocrine Clinic

Osaka, , Japan

Site Status

Kibounomori Clinic

Osaka, , Japan

Site Status

Osaka City University Hospital

Osaka, , Japan

Site Status

Yasuhara Children's Clinic

Osaka, , Japan

Site Status

Osaka Women's and Children's Hospital

Osaka, , Japan

Site Status

NTT East Japan Sapporo HP, Diabetes Mellitus & Int med Endo

Sapporo, Hokkaido, , Japan

Site Status

JCHO Sendai Hospital

Sendai-shi, Miyagi-ken, , Japan

Site Status

Omi Medical Center

Shiga, , Japan

Site Status

Hamamatsu-kita-Hospital

Shizuoka, , Japan

Site Status

Hamamatsu Medical Center

Shizuoka, , Japan

Site Status

Shizuoka General Hospital

Shizuoka-shi, Shizuoka-ken, , Japan

Site Status

Tochigi Medical Center Shimotsuga

Tochigi-shi, Tochigi-ken, , Japan

Site Status

Hosaka Kodomo Clinic

Tokyo, , Japan

Site Status

Ehime University Hospital

Toon-shi, Ehime, , Japan

Site Status

Tottori University Hospital_Endocrinology and Metabolism

Tottori, , Japan

Site Status

Yamagata University Hospital, Internal Medicine 3

Yamagata-shi, Yamagata, , Japan

Site Status

Countries

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Japan

Other Identifiers

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U1111-1247-5417

Identifier Type: OTHER

Identifier Source: secondary_id

NN8640-4638

Identifier Type: -

Identifier Source: org_study_id

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