Exclusive Enteral Nutrition for Remissionof Crohn's Diseases After Surgery

NCT ID: NCT05214430

Last Updated: 2023-10-17

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

84 participants

Study Classification

INTERVENTIONAL

Study Start Date

2020-01-01

Study Completion Date

2023-07-31

Brief Summary

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For patients with Crohn's diseases undergoing surgery,whether postoperative exclusive enteral nutrition(EEN) could delay the endoscopic relapse needs exploration.The trial will investigate the efficacy of postoperative EEN for maintaining disease remission.

Detailed Description

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Conditions

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Crohn Disease in Remission

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

PREVENTION

Blinding Strategy

NONE

Study Groups

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3 months exclusive enteral nutrition after surgery

3 months exclusive enteral nutrition after surgery

Group Type EXPERIMENTAL

3 months exclusive enteral nutrition after surgery

Intervention Type OTHER

patients underwent intestinal resection and anastomosis in this arm will given over 3 months exclusive enteral nutrition,and free diet after 3 months.

less than 1 months exclusive enteral nutrition after surgery

less than 1 months exclusive enteral nutrition after surgery

Group Type EXPERIMENTAL

3 months exclusive enteral nutrition after surgery

Intervention Type OTHER

patients underwent intestinal resection and anastomosis in this arm will given over 3 months exclusive enteral nutrition,and free diet after 3 months.

Interventions

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3 months exclusive enteral nutrition after surgery

patients underwent intestinal resection and anastomosis in this arm will given over 3 months exclusive enteral nutrition,and free diet after 3 months.

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

\- CD patients who undergoing bowel resection with anastomosis

Exclusion Criteria

* patients who received stoma creation
Minimum Eligible Age

18 Years

Maximum Eligible Age

60 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Jinling Hospital, China

OTHER

Sponsor Role lead

Responsible Party

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Zhu Weiming

Jinling Hospital, China

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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General Surgery Institute,Jinling Hospital,Nanjing,Jiangsu,China

Nanjing, Jiangsu, China

Site Status

Countries

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China

References

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Duan M, Lu M, Diao Y, Cao L, Wu Q, Liu Y, Gong J, Zhu W, Li Y. Azathioprine Plus Exclusive Enteral Nutrition Versus Azathioprine Monotherapy for the Prevention of Postoperative Recurrence in Patients with Crohn's Disease: An Open-Label, Single-Centre, Randomized Controlled Trial. J Crohns Colitis. 2024 Aug 6;18(7):1113-1121. doi: 10.1093/ecco-jcc/jjae015.

Reference Type DERIVED
PMID: 38253914 (View on PubMed)

Other Identifiers

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jinlingH202001

Identifier Type: -

Identifier Source: org_study_id

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