Trial Outcomes & Findings for Tailoring Online Continence Promotion (NCT NCT05183217)

NCT ID: NCT05183217

Last Updated: 2025-05-25

Results Overview

Proportion of participants who engage with online MOM at least 4 times during weeks 0-4 in the group with (test) and without (control) tailoring.

Recruitment status

COMPLETED

Study phase

NA

Target enrollment

445 participants

Primary outcome timeframe

0-4 weeks

Results posted on

2025-05-25

Participant Flow

Participant milestones

Participant milestones
Measure
Online Continence Promotion Program Without Tailoring
Participants will be allocated to the online continence promotion program without tailoring. Online Continence promotion program without tailoring: The online continence promotion program has five sections (Introduction, Exercise, Bladder, Bowels, Care Seeking) that build knowledge, self-efficacy, and skills to set action and coping plans relevant to a participant's symptoms. This online program is based on an in-person, small-group program that has demonstrated effectiveness to improve both urinary and bowel incontinence in women age 50 and above. Participants will receive automated weekly reminders reminding them to re-visit the program, regardless of their individual user activity.
Online Continence Promotion Program With Tailoring
Participants will be allocated to the online continence promotion program with tailoring. Online Continence promotion program with tailoring: The online continence promotion program has five sections (Introduction, Exercise, Bladder, Bowels, Care Seeking) that build knowledge, self-efficacy, and skills to set action and coping plans relevant to a participant's symptoms. This online program is based on an in-person, small-group program that has demonstrated effectiveness to improve both urinary and bowel incontinence in women age 50 and above. Participants will receive tailored "output" (personalized cues, emphasis on relevant content, individualized and tailored reminders about their goals) based on a computer algorithm incorporating unique user "inputs" (individual factors). Inputs will be reassessed every 2 weeks for retailoring so that personalization evolves over the course of the intervention.
Overall Study
STARTED
226
219
Overall Study
COMPLETED
225
218
Overall Study
NOT COMPLETED
1
1

Reasons for withdrawal

Reasons for withdrawal
Measure
Online Continence Promotion Program Without Tailoring
Participants will be allocated to the online continence promotion program without tailoring. Online Continence promotion program without tailoring: The online continence promotion program has five sections (Introduction, Exercise, Bladder, Bowels, Care Seeking) that build knowledge, self-efficacy, and skills to set action and coping plans relevant to a participant's symptoms. This online program is based on an in-person, small-group program that has demonstrated effectiveness to improve both urinary and bowel incontinence in women age 50 and above. Participants will receive automated weekly reminders reminding them to re-visit the program, regardless of their individual user activity.
Online Continence Promotion Program With Tailoring
Participants will be allocated to the online continence promotion program with tailoring. Online Continence promotion program with tailoring: The online continence promotion program has five sections (Introduction, Exercise, Bladder, Bowels, Care Seeking) that build knowledge, self-efficacy, and skills to set action and coping plans relevant to a participant's symptoms. This online program is based on an in-person, small-group program that has demonstrated effectiveness to improve both urinary and bowel incontinence in women age 50 and above. Participants will receive tailored "output" (personalized cues, emphasis on relevant content, individualized and tailored reminders about their goals) based on a computer algorithm incorporating unique user "inputs" (individual factors). Inputs will be reassessed every 2 weeks for retailoring so that personalization evolves over the course of the intervention.
Overall Study
Withdrawal by Subject
1
1

Baseline Characteristics

Tailoring Online Continence Promotion

Baseline characteristics by cohort

Baseline characteristics by cohort
Measure
Online Continence Promotion Program Without Tailoring
n=226 Participants
Participants will be allocated to the online continence promotion program without tailoring. Online Continence promotion program without tailoring: The online continence promotion program has five sections (Introduction, Exercise, Bladder, Bowels, Care Seeking) that build knowledge, self-efficacy, and skills to set action and coping plans relevant to a participant's symptoms. This online program is based on an in-person, small-group program that has demonstrated effectiveness to improve both urinary and bowel incontinence in women age 50 and above. Participants will receive automated weekly reminders reminding them to re-visit the program, regardless of their individual user activity.
Online Continence Promotion Program With Tailoring
n=219 Participants
Participants will be allocated to the online continence promotion program with tailoring. Online Continence promotion program with tailoring: The online continence promotion program has five sections (Introduction, Exercise, Bladder, Bowels, Care Seeking) that build knowledge, self-efficacy, and skills to set action and coping plans relevant to a participant's symptoms. This online program is based on an in-person, small-group program that has demonstrated effectiveness to improve both urinary and bowel incontinence in women age 50 and above. Participants will receive tailored "output" (personalized cues, emphasis on relevant content, individualized and tailored reminders about their goals) based on a computer algorithm incorporating unique user "inputs" (individual factors). Inputs will be reassessed every 2 weeks for retailoring so that personalization evolves over the course of the intervention.
Total
n=445 Participants
Total of all reporting groups
Age, Continuous
58 years
n=5 Participants
58 years
n=7 Participants
58 years
n=5 Participants
Sex: Female, Male
Female
226 Participants
n=5 Participants
219 Participants
n=7 Participants
445 Participants
n=5 Participants
Sex: Female, Male
Male
0 Participants
n=5 Participants
0 Participants
n=7 Participants
0 Participants
n=5 Participants
Ethnicity (NIH/OMB)
Hispanic or Latino
5 Participants
n=5 Participants
4 Participants
n=7 Participants
9 Participants
n=5 Participants
Ethnicity (NIH/OMB)
Not Hispanic or Latino
219 Participants
n=5 Participants
212 Participants
n=7 Participants
431 Participants
n=5 Participants
Ethnicity (NIH/OMB)
Unknown or Not Reported
2 Participants
n=5 Participants
3 Participants
n=7 Participants
5 Participants
n=5 Participants
Race (NIH/OMB)
American Indian or Alaska Native
4 Participants
n=5 Participants
2 Participants
n=7 Participants
6 Participants
n=5 Participants
Race (NIH/OMB)
Asian
3 Participants
n=5 Participants
3 Participants
n=7 Participants
6 Participants
n=5 Participants
Race (NIH/OMB)
Native Hawaiian or Other Pacific Islander
0 Participants
n=5 Participants
0 Participants
n=7 Participants
0 Participants
n=5 Participants
Race (NIH/OMB)
Black or African American
41 Participants
n=5 Participants
34 Participants
n=7 Participants
75 Participants
n=5 Participants
Race (NIH/OMB)
White
174 Participants
n=5 Participants
175 Participants
n=7 Participants
349 Participants
n=5 Participants
Race (NIH/OMB)
More than one race
2 Participants
n=5 Participants
4 Participants
n=7 Participants
6 Participants
n=5 Participants
Race (NIH/OMB)
Unknown or Not Reported
2 Participants
n=5 Participants
1 Participants
n=7 Participants
3 Participants
n=5 Participants
Region of Enrollment
United States
226 participants
n=5 Participants
219 participants
n=7 Participants
444 participants
n=5 Participants
Height
165 Centimeters
n=5 Participants
165 Centimeters
n=7 Participants
165 Centimeters
n=5 Participants
Weight
77 kilograms
n=5 Participants
75 kilograms
n=7 Participants
76 kilograms
n=5 Participants
Body mass index
28 kg/m^2
n=5 Participants
27 kg/m^2
n=7 Participants
27.5 kg/m^2
n=5 Participants

PRIMARY outcome

Timeframe: 0-4 weeks

Proportion of participants who engage with online MOM at least 4 times during weeks 0-4 in the group with (test) and without (control) tailoring.

Outcome measures

Outcome measures
Measure
Online Continence Promotion Program Without Tailoring
n=226 Participants
The online continence promotion program has five sections (Introduction, Exercise, Bladder, Bowels, Care Seeking) that build knowledge, self-efficacy, and skills to set action and coping plans relevant to a participant's symptoms. This online program is based on an in-person, small-group program that has demonstrated effectiveness to improve both urinary and bowel incontinence in women age 50 and above. Participants will receive automated weekly reminders reminding them to re-visit the program, regardless of their individual user activity.
Online Continence Promotion Program With Tailoring
n=219 Participants
The online continence promotion program has five sections (Introduction, Exercise, Bladder, Bowels, Care Seeking) that build knowledge, self-efficacy, and skills to set action and coping plans relevant to a participant's symptoms. This online program is based on an in-person, small-group program that has demonstrated effectiveness to improve both urinary and bowel incontinence in women age 50 and above. Participants will receive tailored "output" (personalized cues, emphasis on relevant content, individualized and tailored reminders about their goals) based on a computer algorithm incorporating unique user "inputs" (individual factors). Inputs will be reassessed every 2 weeks for retailoring so that personalization evolves over the course of the intervention.
User Engagement With Online Mind Over Matter (MOM)
17 Participants
37 Participants

SECONDARY outcome

Timeframe: Baseline, 4, 12, and 24 weeks

Frequency of pelvic floor muscle exercises

Outcome measures

Outcome data not reported

SECONDARY outcome

Timeframe: Baseline, 4, and 24 weeks

The Geriatric Index for Urinary Incontinence (GSE-UI) is a validated and clinically responsive instrument for older women with urinary incontinence. Participants select a 0-10 score for each of the 12 items, with total scores ranging from 0-120. A higher score is indicative of a higher level of self-efficacy related to urinary incontinence.

Outcome measures

Outcome data not reported

SECONDARY outcome

Timeframe: Baseline, 4, and 24 weeks

Previously, in consultation with Dr. Ralf Schwarzer (Health Action Process Approach developer), the investigators adapted the Generalized Self Efficacy scale for behaviors related to continence promotion (such as pelvic floor muscle exercises).10-items are scored on a 4 point likert scale from 1 (not true at all) to 4 (exactly true) for a total range of scores from 10-40 where higher scores indicate higher self-efficacy.

Outcome measures

Outcome data not reported

SECONDARY outcome

Timeframe: Baseline, 4, and 24 weeks

Number of Participants who report high vs low risk perception, positive vs negative outcome expectations, specific intentions, action or coping plans, barriers and facilitators for health on the program-specific survey of other Health Action Process Approach components.

Outcome measures

Outcome data not reported

SECONDARY outcome

Timeframe: Baseline and 24 weeks

The Barriers to Incontinence Care-Seeking Questionnaire (BICS-Q) contains 14-items framed on a 4-point Likert scale and is validated in women with urinary incontinence. Mean score will be reported, ranging from 1-4 where higher scores indicate increased barriers.

Outcome measures

Outcome data not reported

SECONDARY outcome

Timeframe: Baseline and 24 weeks

The Barriers to Care-seeking for Accidental Bowel Leakage (BCABL) has been validated in women with bowel incontinence. BCABL contains 16 questions framed on a 4-point Likert scale (strongly disagree, somewhat disagree, somewhat agree, strongly agree), for a total possible range of scores from 16-64 where higher scores indicate increased barriers.

Outcome measures

Outcome data not reported

SECONDARY outcome

Timeframe: Baseline, 4, 12, and 24 weeks

ICIQ-UI is a subjective measure of severity of urinary loss and quality of life for those with urinary incontinence. It is scored on a scale from 0-21. Based on the score participant can be placed in four severity categories: slight (1-5), moderate (6-12), severe (13-18) and very severe (19-21)

Outcome measures

Outcome data not reported

SECONDARY outcome

Timeframe: Baseline, 4, 12, and 24 weeks

St. Mark's Incontinence Scale (aka Vaizey) will be used to assess the severity and the outcome of MOM intervention Never: no episodes in the past 4 weeks rarely: 1 episode in the past 4 weeks sometimes: \> 1 episode in the past 4 weeks, but,1 a week; Weekly: 1 or more episodes a week but,1 a day Daily: 1 or more episodes a day Scores will be assigned for each row (Never=0, Rarely=1, Sometimes=2, Weekly=3, Daily=4 ) Score will be added from each row. Cumulative minimum score=0 perfect continence; Cumulative maximum score will be 24= totally incontinence

Outcome measures

Outcome data not reported

SECONDARY outcome

Timeframe: Baseline, 4, 12, and 24 weeks

The Pelvic Floor Impact Questionnaire Short Form (PFIQ-7) is a widely-used validated instrument that assesses condition-specific quality of life. Scores range from 0-300 with higher scores indicating higher symptom bother.

Outcome measures

Outcome data not reported

SECONDARY outcome

Timeframe: 4 and 24 weeks

Patient satisfaction will be measured with the question: How satisfied are you with your progress in this program? (completely, some-what, not at all)

Outcome measures

Outcome data not reported

SECONDARY outcome

Timeframe: 4 and 24 weeks

For EPI, Patients will be asked to estimate how much better they were on a scale from 0% (no better) to 100%(completely better)

Outcome measures

Outcome data not reported

SECONDARY outcome

Timeframe: 4 and 24 weeks

Global perception of improvement (GPI) is a tool for Global Rating of Patient Satisfaction and Perceptions of Improvement. Question asked: Overall, do you feel that you are? Response can be chosen from the options: Much Better, Better, About the same, Worse, Much worse

Outcome measures

Outcome data not reported

SECONDARY outcome

Timeframe: Baseline, 4, 12, and 24 weeks

The 12-item Short Form Health Survey (SF-12) is a validated health-related quality of life questionnaire from which mental and physical component scores can be calculated. Scores on the PCS-12 (Physical Score): range from 23.99938 (difference from USA average: -26.00062) to 56.57706 (difference from USA average: 6.57706). Scores on the MCS-12 (Mental Score): range from 19.06444 (difference from USA average: -30.93556) to 60.75781 (difference from USA average: 10.75781). For both components, higher scores indicate better health-related quality of life.

Outcome measures

Outcome data not reported

OTHER_PRE_SPECIFIED outcome

Timeframe: Baseline to 24 weeks

Comparison of specific program use metrics (number of, minutes spent on, and average intervals between program sessions accessed weekly; number of and specific components accessed) between the two groups and patterns of program use (such as tracking and reminders).

Outcome measures

Outcome data not reported

OTHER_PRE_SPECIFIED outcome

Timeframe: Baseline, 4, 12, and 24 weeks

Proportion of participants in the treatment group compared to the control group with a body mass index (BMI) \>25mg/kg2 at baseline who report weight loss of at least 2 kg.

Outcome measures

Outcome data not reported

OTHER_PRE_SPECIFIED outcome

Timeframe: Baseline, 4, 12, and 24 weeks

Self-reported behavior changes: fluid intake

Outcome measures

Outcome data not reported

OTHER_PRE_SPECIFIED outcome

Timeframe: Baseline, 4, 12, and 24 weeks

Self-reported behavior changes: change in fiber intake

Outcome measures

Outcome data not reported

OTHER_PRE_SPECIFIED outcome

Timeframe: Baseline, 4, 12, and 24 weeks

Self-reported coping changes: change in types of pad used

Outcome measures

Outcome data not reported

OTHER_PRE_SPECIFIED outcome

Timeframe: Baseline, 4, 12, and 24 weeks

Self-reported coping changes: change in number of pads used

Outcome measures

Outcome data not reported

OTHER_PRE_SPECIFIED outcome

Timeframe: Baseline, 4, 12, and 24 weeks

It will be measured by asking participants question that how much money have they spent on products (such as pads, undergarments, or plugs) to manage their bladder and/or bowel symptoms in the last month.

Outcome measures

Outcome data not reported

Adverse Events

Online Continence Promotion Program Without Tailoring

Serious events: 0 serious events
Other events: 0 other events
Deaths: 0 deaths

Online Continence Promotion Program With Tailoring

Serious events: 0 serious events
Other events: 0 other events
Deaths: 0 deaths

Serious adverse events

Adverse event data not reported

Other adverse events

Adverse event data not reported

Additional Information

Heidi Brown

University of Wisconsin - Madison

Phone: 619-695-4714

Results disclosure agreements

  • Principal investigator is a sponsor employee
  • Publication restrictions are in place