Trial Outcomes & Findings for Total30 Sphere Contact Lenses (NCT NCT05183022)

NCT ID: NCT05183022

Last Updated: 2022-12-16

Results Overview

A visual analog scale (VAS) was used to compare end of day ocular comfort at 16 hours of contact lens wear over the 1 month study (0 to 100 scale with 100 being best).

Recruitment status

COMPLETED

Study phase

NA

Target enrollment

48 participants

Primary outcome timeframe

1 month

Results posted on

2022-12-16

Participant Flow

Participant milestones

Participant milestones
Measure
Total30 Sphere Contact Lenses
All qualified participants will be refit into Total30 Sphere contact lenses. Total30 Sphere Contact Lenses: Participants will be refit into Total30 Sphere contact lenses and followed for 1 month.
Overall Study
STARTED
48
Overall Study
COMPLETED
48
Overall Study
NOT COMPLETED
0

Reasons for withdrawal

Withdrawal data not reported

Baseline Characteristics

Total30 Sphere Contact Lenses

Baseline characteristics by cohort

Baseline characteristics by cohort
Measure
Total30 Sphere Contact Lenses
n=48 Participants
All qualified participants will be refit into Total30 Sphere contact lenses. Total30 Sphere Contact Lenses: Participants will be refit into Total30 Sphere contact lenses and followed for 1 month.
Age, Categorical
<=18 years
0 Participants
n=5 Participants
Age, Categorical
Between 18 and 65 years
48 Participants
n=5 Participants
Age, Categorical
>=65 years
0 Participants
n=5 Participants
Age, Continuous
Total30 Participants
26.2 Years
STANDARD_DEVIATION 5.2 • n=5 Participants
Sex: Female, Male
Female
34 Participants
n=5 Participants
Sex: Female, Male
Male
14 Participants
n=5 Participants
Ethnicity (NIH/OMB)
Hispanic or Latino
2 Participants
n=5 Participants
Ethnicity (NIH/OMB)
Not Hispanic or Latino
46 Participants
n=5 Participants
Ethnicity (NIH/OMB)
Unknown or Not Reported
0 Participants
n=5 Participants
Race (NIH/OMB)
American Indian or Alaska Native
0 Participants
n=5 Participants
Race (NIH/OMB)
Asian
11 Participants
n=5 Participants
Race (NIH/OMB)
Native Hawaiian or Other Pacific Islander
0 Participants
n=5 Participants
Race (NIH/OMB)
Black or African American
5 Participants
n=5 Participants
Race (NIH/OMB)
White
31 Participants
n=5 Participants
Race (NIH/OMB)
More than one race
1 Participants
n=5 Participants
Race (NIH/OMB)
Unknown or Not Reported
0 Participants
n=5 Participants
Region of Enrollment
United States
48 Participants
n=5 Participants

PRIMARY outcome

Timeframe: 1 month

Population: Total30 Contact Lens Wearing Participants

A visual analog scale (VAS) was used to compare end of day ocular comfort at 16 hours of contact lens wear over the 1 month study (0 to 100 scale with 100 being best).

Outcome measures

Outcome measures
Measure
Total30 Sphere Contact Lenses
n=48 Participants
All qualified participants will be refit into Total30 Sphere contact lenses. Total30 Sphere Contact Lenses: Participants will be refit into Total30 Sphere contact lenses and followed for 1 month.
Visual Analog Scale (VAS) Ocular Comfort
Day 1: Comfort at Hour 16
36.66 units on a scale
Standard Deviation 19.11
Visual Analog Scale (VAS) Ocular Comfort
Day 2: Comfort at Hour 16
38.06 units on a scale
Standard Deviation 14.71
Visual Analog Scale (VAS) Ocular Comfort
Day 3: Comfort at hour 16
33.68 units on a scale
Standard Deviation 22.49
Visual Analog Scale (VAS) Ocular Comfort
Day 4: Comfort at hour 16
39.36 units on a scale
Standard Deviation 13.95
Visual Analog Scale (VAS) Ocular Comfort
Day 5: Comfort at hour 16
31.26 units on a scale
Standard Deviation 24.73
Visual Analog Scale (VAS) Ocular Comfort
2 weeks: Comfort at hour 16
33.84 units on a scale
Standard Deviation 23.15
Visual Analog Scale (VAS) Ocular Comfort
1 month: Comfort at hour 16
33.21 units on a scale
Standard Deviation 22.39

Adverse Events

Total30 Sphere Contact Lenses

Serious events: 0 serious events
Other events: 0 other events
Deaths: 0 deaths

Serious adverse events

Adverse event data not reported

Other adverse events

Adverse event data not reported

Additional Information

Andrew D. Pucker, OD, PhD

University of Alabama at Birmingham

Phone: 1-920-579-2900

Results disclosure agreements

  • Principal investigator is a sponsor employee
  • Publication restrictions are in place