Healthcare Costs and Resource Utilization in Aimovig Migraine Patients: a Retrospective Study Using United States Claims Data

NCT ID: NCT05177406

Last Updated: 2022-01-04

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

1839 participants

Study Classification

OBSERVATIONAL

Study Start Date

2020-08-31

Study Completion Date

2020-12-31

Brief Summary

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The proposed study is a retrospective, non-interventional analysis that uses medical and pharmacy claims data in the US from Komodo Health

Detailed Description

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The proposed study is a retrospective, non-interventional analysis that uses medical and pharmacy claims data in the US from Komodo Health.

Study data included adjudicated and paid medical and pharmacy claims in the US between November 1, 2017 and September 1, 2019 provided by Komodo Health.

Conditions

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Migraine

Study Design

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Observational Model Type

COHORT

Study Time Perspective

RETROSPECTIVE

Study Groups

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Full cohort

patients newly initiating Aimovig therapy

Aimovig

Intervention Type OTHER

patients newly initiating Aimovig therapy

Interventions

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Aimovig

patients newly initiating Aimovig therapy

Intervention Type OTHER

Other Intervention Names

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Erenumab

Eligibility Criteria

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Inclusion Criteria

General Cohort

* Adult (18 years or older)
* Newly initiating on Aimovig (no other claims during a 180-day wash-in period)
* Had continuous medical and pharmacy benefit eligibility from 180 days pre-index of Aimovig through 180-days post-index

Primary \& Secondary Objectives Sub-Cohort

\- Had 3 consecutive months with a claim for Aimovig (≤15 days gap between days supply and the subsequent claim to be considered consecutive)

Primary \& Secondary Objectives Cost Sensitivity Analyses Sub-Cohorts

* Had continuous medical and pharmacy benefit eligibility from 180 days pre-index of Aimovig through 270-days post-index to permit assessment of cost outcomes (all-cause and migraine-related) during days 91-270 post-index
* Had continuous medical and pharmacy benefit eligibility from 180 days pre-index of Aimovig to the maximum follow-up time post-index with continuous medical and prescription insurance eligibility until the data end date (September 1, 2019)

Exclusion Criteria

* Patients with any claim for another CGRP-targeted medication (Ajovy or Emgality) during entire study period
Minimum Eligible Age

18 Years

Maximum Eligible Age

85 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Novartis Pharmaceuticals

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Novartis Pharmaceuticals

Role: STUDY_DIRECTOR

Novartis Pharmaceuticals

Locations

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Novartis Investigative Site

East Hanover, New Jersey, United States

Site Status

Countries

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United States

Other Identifiers

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CAMG334A2029

Identifier Type: -

Identifier Source: org_study_id

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