Genotype-phenotype Correlation and Pathogenic Mechanism in Hereditary Ataxia

NCT ID: NCT05160870

Last Updated: 2022-01-12

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Total Enrollment

500 participants

Study Classification

OBSERVATIONAL

Study Start Date

2021-06-30

Study Completion Date

2025-12-25

Brief Summary

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The investigators aimed to find appropriate biomarkers such as serum neurofilament light chain in reflecting disease severity in hereditary ataxia from a large cohort during long-term follow-up. The disease severity is indicated by clinical scales and brain MRI tests.

Detailed Description

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Conditions

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Hereditary Ataxia

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Eligibility Criteria

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Inclusion Criteria

* genetically diagnosed as Spinocerebellar ataxia

Exclusion Criteria

* deny follow-yp
Minimum Eligible Age

18 Years

Maximum Eligible Age

65 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Second Affiliated Hospital, School of Medicine, Zhejiang University

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Locations

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Second Affiliated Hospital, Zhejiang University School of Medicine

Hangzhou, Zhejiang, China

Site Status RECRUITING

Countries

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China

Central Contacts

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Yi Dong

Role: CONTACT

+ 8618367129345

Facility Contacts

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Yi Dong

Role: primary

Other Identifiers

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Wulab-sNfL in HA

Identifier Type: -

Identifier Source: org_study_id

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