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Extracorporal Membrane Oxygenation for Critically Ill Patients With COVID-19

NCT ID: NCT05158816

Last Updated: 2022-12-21

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

295 participants

Study Classification

OBSERVATIONAL

Study Start Date

2021-09-08

Study Completion Date

2022-11-30

Brief Summary

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Retrospective single center analyses of COVID-19 patients admitted to the ICU between 01/02/2020 and 31/07/2021.

Detailed Description

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All adults (\>18 years) with acute hypoxaemic respiratory failure due to diagnosed COVID-19 pneumonia and admitted to ICU from 01/02/2020 until 31/07/2021 were included in the study. Following the World Health Organisation (WHO) protocol 19, laboratory confirmation of COVID-19 infection was defined as a positive result on polymerase chain reaction (PCR) assays of nasopharyngeal swab samples or bronchoalveolar lavage. Only laboratory-confirmed patients were included in the analysis.

Additional data collection

Additional collected parameters are listed below and are collected as a standard-of-care in our hospital:

* Demographics: i.e age, gender, BMI
* DNR code
* Comorbidities: smoking, obesity, hypertension, diabetes, cardiovascular disease, respiratory disease, malignancies, renal failure (AKI), liver failure, gastrointestinal disease, neurological conditions, mental state, other
* Symptoms at the time of admission to ICU: i.e fever, body temperature, dyspnoea, headache, diarrhea etc…
* Laboratory results of all standard parameters measured
* Treatment: antiviral agents, antibiotics, etc…
* Complications: shock, heart failure, sepsis, stroke, etc…
* Ventilation: method, PEEP, FiO2, P/F ratio ..

Conditions

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COVID-19

Keywords

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ECMO

Study Design

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Observational Model Type

COHORT

Study Time Perspective

RETROSPECTIVE

Study Groups

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COVID-19 patients

COVID-19 patients admitted to the ICU

ECMO

Intervention Type PROCEDURE

Patients undergoing extracorporeal membrane oxygenation

Interventions

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ECMO

Patients undergoing extracorporeal membrane oxygenation

Intervention Type PROCEDURE

Eligibility Criteria

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Inclusion Criteria

* All adult COVID-19 patients (\>18 years) admitted to the ICU between 01/02/2020 and 31/07/2021 with a laboratory confirmation of COVID-19 infection with a positive result on polymerase chain reaction (PCR) assays of nasopharyngeal swab samples or bronchoalveolar lavage

Exclusion Criteria

* All adult patients admitted for other reasons to the ICU (no COVID-19 pneumonia)
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Jessa Hospital

OTHER

Sponsor Role lead

Responsible Party

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Stessel Björn

Principal Investigator

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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Jessa Hospital

Hasselt, Limburg, Belgium

Site Status

Countries

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Belgium

References

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Madrid-Valero JJ, Ware J, Allen JM, Boughton CK, Hartnell S, Wilinska ME, Thankamony A, de Beaufort C, Schierloh U, Campbell FM, Sibayan J, Bocchino LE, Kollman C, Hovorka R, Gregory AM, Consortium K. Sleep Quality and Quantity in Caregivers of Children with Type 1 Diabetes Using Closed-Loop Insulin Delivery or a Sensor-Augmented Pump. Pediatr Diabetes. 2023 Jun 13;2023:7937007. doi: 10.1155/2023/7937007. eCollection 2023.

Reference Type DERIVED
PMID: 40303271 (View on PubMed)

Stessel B, Bin Saad M, Ullrick L, Geebelen L, Lehaen J, Timmermans PJ, Van Tornout M, Callebaut I, Vandenbrande J, Dubois J. Extracorporeal Membrane Oxygenation to Support COVID-19 Patients: A Propensity-Matched Cohort Study. Crit Care Res Pract. 2023 Jun 12;2023:5101456. doi: 10.1155/2023/5101456. eCollection 2023.

Reference Type DERIVED
PMID: 37342313 (View on PubMed)

Other Identifiers

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f/2021/097

Identifier Type: -

Identifier Source: org_study_id