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The Relationship Between Hormone Sensitivity and Imaging of Idiopathic Interstitial Pneumonia by Artificial Intelligence

NCT ID: NCT05146934

Last Updated: 2021-12-07

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

150 participants

Study Classification

OBSERVATIONAL

Study Start Date

2019-12-30

Study Completion Date

2021-06-30

Brief Summary

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Application of artificial intelligence deep learning algorithm to analyze the relationship between hormone sensitivity of idiopathic interstitial pneumonia and imaging features of high resolution CT.

Detailed Description

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Methods: the medical records and chest high-resolution CT images of patients with idiopathic interstitial pneumonia admitted to the respiratory department of the Third Hospital of Peking University from June 1, 2012 to December 31, 2020 were retrospectively analyzed.Application of artificial intelligence deep learning neural convolution network method to create recognition technology of different imaging features.Including ground glass, mesh, honeycomb, nodule or consolidation, the model was established. IIP patients were divided into hormone sensitive group and hormone insensitive group according to whether the use of hormone was effective or not.Logistic regression analysis was used to analyze the correlation between statistically significant parameters and hormone sensitivity.Artificial intelligence was used to establish the correlation model between imaging features and clinical data and hormone sensitivity.

Conditions

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Idiopathic Interstitial Pneumonia

Keywords

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Hormone sensitivity imaging features artificial intelligence

Study Design

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Observational Model Type

CASE_CONTROL

Study Time Perspective

RETROSPECTIVE

Study Groups

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Hormone sensitive group

Prednisone, 0.5mg/kgqd, 3-6months

high resolution CT

Intervention Type RADIATION

Ground glass，honeycomb，reticulation, consolidation

Hormone insensitivity group

Prednisone, 0.5mg/kgqd, 3-6months

high resolution CT

Intervention Type RADIATION

Ground glass，honeycomb，reticulation, consolidation

Interventions

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high resolution CT

Ground glass，honeycomb，reticulation, consolidation

Intervention Type RADIATION

Eligibility Criteria

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Inclusion Criteria

Clinical-pathological-radiology diagnosis of idiopathic interstitial pneumonia Hormone therapy was used; The follow-up data were complete, and the effect of hormone use could be judged.

Exclusion Criteria

Lung infection disease; Heart failure; Connective tissue disease; IIP Without hormone therapy ; IIP but the follow-up data were incomplete, and the effect of hormone use could not be judged.
Minimum Eligible Age

18 Years

Maximum Eligible Age

90 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Peking University Third Hospital

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Bei He

Role: PRINCIPAL_INVESTIGATOR

Peking University Third Hospital Respiratory and critical care department

Locations

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Peking University Third Hospital

Beijing, Beijing Municipality, China

Site Status

Countries

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China

Other Identifiers

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LM2019173

Identifier Type: -

Identifier Source: org_study_id