German Cardiac Arrest Registry

NCT ID: NCT05142124

Last Updated: 2025-06-25

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Total Enrollment

400 participants

Study Classification

OBSERVATIONAL

Study Start Date

2021-07-21

Study Completion Date

2026-06-30

Brief Summary

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In Germany, 70.000 to 100.000 patients suffer from out-of-hospital cardiac arrest (OHCA) every year. More than half of these are due to cardiac causes. Despite the medical progress over the last decades, rates of survival with good neurological outcome remain low. For many below-mentioned issues, no adequate evidence from randomized trials is available. Therefore, a systematic and standardized recording of the pre-clinical, clinical and post-clinical treatment course and of the clinical outcomes of OHCA patients is essential to improve patient care. Aim of the German Cardiac Arrest Registry (G-CAR) is to achieve a better understanding of the disease entity, leading to an optimized treatment of OHCA patients. The recorded data include information on demographic and psychosocial aspects, course of the disease, clinical, laboratory and other examinations as well as treatment modalities in patients with OHCA due to a cardiac cause.

Detailed Description

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Conditions

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Out-of-hospital Cardiac Arrest

Study Design

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Observational Model Type

CASE_ONLY

Study Time Perspective

PROSPECTIVE

Eligibility Criteria

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Inclusion Criteria

* patients with out-of-hospital cardiac arrest with assumed cardiovascular cause

Exclusion Criteria

* rejection of register participation by patient or legal representative
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Helios Health Institute GmbH

OTHER

Sponsor Role collaborator

Heart Center Leipzig - University Hospital

OTHER

Sponsor Role collaborator

IHF GmbH - Institut für Herzinfarktforschung

OTHER

Sponsor Role collaborator

Universitätsklinikum Hamburg-Eppendorf

OTHER

Sponsor Role collaborator

St. Antonius Hospital

OTHER

Sponsor Role collaborator

Klinikum Ludwigshafen

OTHER

Sponsor Role collaborator

University of Magdeburg

OTHER

Sponsor Role collaborator

Charite University, Berlin, Germany

OTHER

Sponsor Role collaborator

University Hospital of Cologne

OTHER

Sponsor Role collaborator

Leipzig Heart Science gGmbH

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Janine Pöss, Dr.

Role: STUDY_CHAIR

Heart Center Leipzig at University of Leipzig, Department of Internal Medicine/Cardiology

Locations

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CHARITE - Universitätsmedizin Berlin - Campus Virchow Klinikum

Berlin, State of Berlin, Germany

Site Status ACTIVE_NOT_RECRUITING

SLK-Kliniken Heilbronn - Klinikum am Plattenwald

Bad Friedrichshall, , Germany

Site Status RECRUITING

Charité Universitätsmedizin Berlin - Deutsches Herzzentrum Berlin

Berlin, , Germany

Site Status RECRUITING

Universitätsklinikum Bonn

Bonn, , Germany

Site Status RECRUITING

Bremer Institut für Herz- und Kreislaufforschung am Klinikum Links der Weser

Bremen, , Germany

Site Status RECRUITING

Herzzentrum der Universität zu Köln

Cologne, , Germany

Site Status RECRUITING

Herzzentrum Dresden GmbH

Dresden, , Germany

Site Status ACTIVE_NOT_RECRUITING

Universitätsklinikum Düsseldorf - Klinik für Kardiologie, Pneumologie und Angiologie

Düsseldorf, , Germany

Site Status RECRUITING

Elisabeth Krankenhaus Essen - Klinik für Akut- und Notfallmedizin

Essen, , Germany

Site Status RECRUITING

Klinikum Frankfurt Höchst

Frankfurt, , Germany

Site Status RECRUITING

Universitätsklinikum Halle (Saale)

Halle, , Germany

Site Status RECRUITING

Universitäres Herz- und Gefäßzentrum Hamburg

Hamburg, , Germany

Site Status RECRUITING

Asklepios Klinik St- Georg Hamburg

Hamburg, , Germany

Site Status RECRUITING

SLK-Kliniken Heilbronn - Klinikum am Gesundbrunnen

Heilbronn, , Germany

Site Status RECRUITING

Universitätsklinikum des Saarlandes

Homburg, , Germany

Site Status RECRUITING

Heart Center Leipzig at University of Leipzig, Department of Internal Medicine/Cardiology

Leipzig, , Germany

Site Status RECRUITING

Klinikum der Stadt Ludwigshafen gGmbH

Ludwigshafen, , Germany

Site Status RECRUITING

Herzzentrum Lübeck

Lübeck, , Germany

Site Status RECRUITING

Universitätsklinikum Mannheim

Mannheim, , Germany

Site Status RECRUITING

Klinikum der Universität München

München, , Germany

Site Status RECRUITING

Marienhaus Klinikum Hetzelstift

Neustadt, , Germany

Site Status RECRUITING

Hegau-Bodensee Klinikum

Singen, , Germany

Site Status RECRUITING

Hegau-Bodensee-Klinikum Singen

Singen, , Germany

Site Status NOT_YET_RECRUITING

Schwarzwald-Baar Klinikum VS

Villingen-Schwenningen, , Germany

Site Status RECRUITING

Dr. Horst Schmidt Kliniken

Wiesbaden, , Germany

Site Status ACTIVE_NOT_RECRUITING

Countries

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Germany

Central Contacts

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Janine Pöss, Dr.

Role: CONTACT

+49 341 865 ext. 1428

Holger Thiele, Prof.

Role: CONTACT

+49 341 865 ext. 1428

Facility Contacts

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Thomas Dengler, MD, Prof. Dr.

Role: primary

Wulf Knie, MD

Role: primary

Sebastian Zimmer, Prof. Dr.

Role: primary

Philip R Goody, Dr.

Role: backup

Harm Wienbergen, Prof.

Role: primary

Roman Pflister, Prof.

Role: primary

Malte Kelm, Prof.

Role: primary

Ralf Westenfeld, PD Dr.

Role: backup

Ingo Voigt, Dr.

Role: primary

Daniel Bock, Dr.

Role: primary

Daniel Sedding, Prof. Dr.

Role: primary

Jochen Dutzmann, Dr.

Role: backup

Christoph Sinning, PD Dr.

Role: primary

Eike P Tigges, Dr.

Role: primary

Marcus Hennersdorf, MD, Prof. Dr.

Role: primary

Andreas Link, Prof.

Role: primary

Janine Pöss, Dr.

Role: primary

+49 341 865 ext. 1428

Holger Thiele, Prof.

Role: backup

Uwe Zeymer, Prof.

Role: primary

Tobias Graf, Dr.

Role: primary

Ibrahim Akin, Prof. Dr. med.

Role: primary

Clemens Scherer, MD

Role: primary

Patrick Swojanowsky, Dr.

Role: primary

Stephan Richter, MD

Role: primary

Stephan Richter, MD

Role: primary

Sebastian Ewen, MD

Role: primary

References

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Poss J, Sinning C, Rossberg M, Hosler N, Ouarrak T, Bottiger BW, Ewen S, Wienbergen H, Voss F, Dutzmann J, Tigges E, Voigt I, Freund A, Desch S, Michels G, Thiele H, Zeymer U; G-CAR Investigators. German Cardiac Arrest Registry (G-CAR)-results of the pilot phase. Clin Res Cardiol. 2025 Oct;114(10):1270-1279. doi: 10.1007/s00392-024-02468-5. Epub 2024 Jun 13.

Reference Type DERIVED
PMID: 38869632 (View on PubMed)

Poss J, Sinning C, Schreiner I, Apfelbacher C, Drewitz KP, Hosler N, Schneider S, Pieske B, Bottiger BW, Ewen S, Wienbergen H, Kelm M, Bock D, Graf T, Adler C, Dutzmann J, Knie W, Orban M, Zeymer U, Michels G, Thiele H; G-CAR Investigators. German Cardiac Arrest Registry: rationale and design of G-CAR. Clin Res Cardiol. 2023 Apr;112(4):455-463. doi: 10.1007/s00392-022-02044-9. Epub 2022 Jun 21.

Reference Type DERIVED
PMID: 35729429 (View on PubMed)

Other Identifiers

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2020-0396

Identifier Type: -

Identifier Source: org_study_id

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