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Proton and Carbon Ion Radiotherapy for Cervical Cancer

NCT ID: NCT05141825

Last Updated: 2021-12-02

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

16 participants

Study Classification

INTERVENTIONAL

Study Start Date

2016-01-01

Study Completion Date

2021-10-31

Brief Summary

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The aim of this study is to evaluate the toxicity and tolerance of proton and carbon ion radiotherapy (PCRT) for cervical cancer.

Detailed Description

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To retrospectively analyze cervical cancer patients received radical proton and carbon radiotherapy in our center. The acute and late toxicities, overall survival (OS), local control rate (LC), progression-free survival (PFS) and distant metastasis-free survival (DMFS) were analyzed.

Conditions

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Cervical Cancer

Keywords

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proton and carbon ion radiotherapy

Study Design

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Allocation Method

NA

Intervention Model

SINGLE_GROUP

Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Study Groups

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proton and carbon ion radiotherapy

proton and carbon ion radiotherapy

Group Type EXPERIMENTAL

proton and carbon ion radiotherapy

Intervention Type RADIATION

proton and carbon ion radiotherapy

Interventions

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proton and carbon ion radiotherapy

proton and carbon ion radiotherapy

Intervention Type RADIATION

Eligibility Criteria

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Inclusion Criteria

1. . histologically diagnosis of squamous cell carcinoma of the cervix;
2. . International Federation of Gynecology and Obstetrics (FIGO) stage (2014) IB2 - IIIB, without rectum invasion; or FIGO stage IA - IB1, who refused surgery or were contraindication for surgery due to comorbidity diseases;
3. . received proton and carbon ion radiotherapy (PCRT) with or without chemotherapy for curative intention;
4. . Follow-up data available.

Exclusion Criteria

1. a previous history of other malignancy;
2. squamous cell carcinoma of the cervix patients who had received surgery;
3. rectum was invaded.
Minimum Eligible Age

18 Years

Eligible Sex

FEMALE

Accepts Healthy Volunteers

No

Sponsors

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Shanghai Proton and Heavy Ion Center

OTHER

Sponsor Role lead

Responsible Party

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Zhan Yu

physician of abdorminal and pelvic oncology department

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Qing Zhang, MD

Role: PRINCIPAL_INVESTIGATOR

Shanghai Proton and Heavy Ion Center

Other Identifiers

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SPHIC-TR-CERC-2021-01

Identifier Type: -

Identifier Source: org_study_id