Hemostasis Assesment After Application of Lyophilisate Collagen in Nail Surgery

NCT ID: NCT05140161

Last Updated: 2021-12-01

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Clinical Phase

NA

Total Enrollment

98 participants

Study Classification

INTERVENTIONAL

Study Start Date

2021-12-20

Study Completion Date

2022-02-21

Brief Summary

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The objective of this study is to evaluate the hemostatic capacity of two types of collagen hemostatic sponges in nail surgery.

It is a randomized triple-blind clinical trial with two experimental groups (medium porosity collagen and high porosity collagen) and control group ( non collagen).

Detailed Description

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To evaluate bleeding, all patients with onychocryptosis will be operated on with the same technique.

In the experimental groups, once the surgical procedure has been completed on both edges of the nail, hemostatic collagen will be applied in the experimental groups (experimental group 1- medium porosity collagen and experimental group 2-high porosity collagen) In all groups, including the control, once the intervention was finished, the same bandage was performed with the same number of gauze pads.

At 72 hours, the gauze set will be removed to weigh it using a precision balance and quantitatively evaluate the amount of bleeding.

In this way, a comparative study can be carried out between the 3 groups and determine if there are statistically significant differences or not, and can determine if lyophilized hemostatic collagen is useful in nail surgery and if there are significant differences between both experimental groups, determining if the percentage of porosity in a hemostatic is relevant in the hemostatic effect.

Conditions

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Nails, Ingrown Coagulation Defect; Bleeding

Keywords

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collagen nail ingrown bleeding surgery

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

TRIPLE

Participants Investigators Outcome Assessors

Study Groups

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Collagen 1

Medium porosity collagen sponge is used in the operated nail grooves. The hallux is covered with a non-stick dressing, five gauze surrounding it and a cohesive bandage

Group Type EXPERIMENTAL

collagen

Intervention Type DEVICE

use of hemostatic device in order to reduce bleeding in nail surgery

Collagen 2

High porosity collagen sponge is used in the operated nail grooves. The hallux is covered with a non-stick dressing, five gauze surrounding it and a cohesive bandage

Group Type EXPERIMENTAL

collagen

Intervention Type DEVICE

use of hemostatic device in order to reduce bleeding in nail surgery

Control group

No hemostatic device is used in the nail grooves. No hemostatic device is used in the nail grooves. Only non-stick dressing, five gauze pads and cohesive bandage are used

Group Type NO_INTERVENTION

No interventions assigned to this group

Interventions

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collagen

use of hemostatic device in order to reduce bleeding in nail surgery

Intervention Type DEVICE

Eligibility Criteria

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Inclusion Criteria

* STADIUM I, II, or III (Kline classification) without infective onychocryptosis (cellulitis) on both edges of the Hallux
* Susceptible to phenol-alcohol technique with Suppan I modification

Exclusion Criteria

* Platelet Antiplatelet Therapy
* Oral Anticoagulant Therapy
* History of congenital or acquired Hemorrhagic Syndrome
* Alteration in the following parameters (platelet count, prothrombin time, activated thromboplastin time, and plasma fibrinogen)
Minimum Eligible Age

15 Years

Maximum Eligible Age

70 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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University of Seville

OTHER

Sponsor Role lead

Responsible Party

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Antonio Córdoba-Fernández PhD

PhD, Principal Investigator, Clinical Professor

Responsibility Role PRINCIPAL_INVESTIGATOR

Central Contacts

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ANTONIO CÓRDOBA FERNÁNDEZ, PHD

Role: CONTACT

Phone: +34 685860512

Email: [email protected]

Other Identifiers

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1206-N-15

Identifier Type: -

Identifier Source: org_study_id