Peripheral Choroidal Layer Response

NCT ID: NCT05132140

Last Updated: 2021-11-30

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.

Recruitment Status

UNKNOWN

Clinical Phase

NA

Total Enrollment

40 participants

Study Classification

INTERVENTIONAL

Study Start Date

2021-11-30

Study Completion Date

2023-05-31

Brief Summary

Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.

The study aims to examine how the vascular layer of the eyeball (choroidal layer) responds when part of the visual field is exposed to specially generated visual stimulus. The study goal will be accomplished by producing specific blur visual stimulus at a particular visual field position and measure any consistent thickness change pattern in the choroidal layer.

We propose to test the hypothesis that regional changes in the choroidal thickness may be induced differently after short-term exposure to specific visual stimuli.

Detailed Description

Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.

Conditions

See the medical conditions and disease areas that this research is targeting or investigating.

Myopia

Study Design

Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.

Allocation Method

NA

Intervention Model

SINGLE_GROUP

Primary Study Purpose

BASIC_SCIENCE

Blinding Strategy

NONE

Study Groups

Review each arm or cohort in the study, along with the interventions and objectives associated with them.

normal healthy group

Adaptive optics system: this system controls the optical quality of the eye at the peripheral visual field temporarily.

Group Type EXPERIMENTAL

adaptive optics system

Intervention Type DEVICE

the system consists of a wavefront sensor and a deformable mirror that measure and correct (or modify) the eye's optical imperfections (aberrations).

Interventions

Learn about the drugs, procedures, or behavioral strategies being tested and how they are applied within this trial.

adaptive optics system

the system consists of a wavefront sensor and a deformable mirror that measure and correct (or modify) the eye's optical imperfections (aberrations).

Intervention Type DEVICE

Eligibility Criteria

Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.

Inclusion Criteria

A person is eligible for inclusion in the study if he/she:

* Is between the ages of 18 and 40 yrs old
* Has normal best corrected visual acuity being 20/20 or better
* Has spherical refractive error between +1.00D and -6.00D.
* Is capable of fixating on the target.
* Has no prior ocular surgery.
* Has no ocular pathology except keratoconus.
* Can tolerate dilating eye drops

Exclusion Criteria

A person will be excluded from the study if he/she:

* Does not fall within above mentioned age group.
* Has chronic or systemic eye disease that would interfere with pupil dilation via eye drops.
* Underwent ocular surgeries or history of ocular trauma
* Has shallow anterior chamber angle and/or glaucoma.
* Has clinically significant dry eye.
* Has signs of any choroidal or retinal pathology, and abnormalities in the visual pathway
* Has spherical refractive error that exceeds the limits outlined above.
* Has binocular anomalies (e.g. convergence insufficiency, strabismus, pseudo-myopia, amblyopia).
* Is an adult unable to consent
* Is an individual who is not yet adult (infants, children, teenagers)
* Is a pregnant woman
* Is a prisoner
* Is a student for whom you have direct access to/influence on grades
* Is an economically and/or educationally disadvantaged person
Minimum Eligible Age

18 Years

Maximum Eligible Age

40 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

Meet the organizations funding or collaborating on the study and learn about their roles.

University of Houston

OTHER

Sponsor Role lead

Responsible Party

Identify the individual or organization who holds primary responsibility for the study information submitted to regulators.

Geunyoung Yoon

Professor

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

Learn about the lead researchers overseeing the trial and their institutional affiliations.

Geunyoung Yoon, PhD

Role: PRINCIPAL_INVESTIGATOR

University of Houston

Central Contacts

Reach out to these primary contacts for questions about participation or study logistics.

Geunyoung Yoon, PhD

Role: CONTACT

Phone: 7137437860

Email: [email protected]

Dibyendu Pusti, PhD

Role: CONTACT

Phone: 5854069837

Email: [email protected]

Other Identifiers

Review additional registry numbers or institutional identifiers associated with this trial.

STUDY00003210

Identifier Type: -

Identifier Source: org_study_id