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The Association Between Periodontal Disease and Malnutrition in a Group of Elderly People in Thailand.

NCT ID: NCT05129826

Last Updated: 2021-11-22

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

78 participants

Study Classification

INTERVENTIONAL

Study Start Date

2019-11-01

Study Completion Date

2021-05-01

Brief Summary

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This study will be determine the association between periodontitis and malnutrition status in older adult.

Detailed Description

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Ageing may accompany with an accumulation of diseases and impairments cause by physiological, socioeconomic and psychological changes. The older adults are more prone to nutritional deficiencies due to combination of factors such as ageing, excessive polypharmacy, general health decline, poor socioeconomic status, cognitive decline, poor appetite, impaired efficacy of swallowing and limit eating ability.

Periodontitis is a multifactorial disease predominantly a bacterial infection involving the dental biofilm or dental plaque. Periodontitis increases in extent and severity across a large proportion of the human population with ageing. The effects of ageing on the immune system include distinct alterations in both innate and adaptive immune-cell function and effector biomolecules, resulting in processes reflecting immunosenescence, immunoactivation and inflammaging. Moreover, genetic contribution alters immunity and inflammation that play a role in the dysregulation of host responses in ageing. The combination of chronic antigenic burden and uncontrolled inflammatory response can enhance immunosenescence and ageing-associated disease. Periodontitis also has an effect on food intake, nutritional status and quality of life in older adults.

However the relationship between chronic periodontitis and malnutrition in older adult is not clear and needs further study. In this study will be determine the association between periodontitis and malnutrition status in older adult.

Conditions

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Periodontal Diseases Malnutrition

Keywords

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periodontal disease malnutrition older adult

Study Design

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Allocation Method

NA

Intervention Model

SINGLE_GROUP

Subjects who has aged ≥ 60 years old, not receive periodontal treatment within the previous 6 months, able to read Thai and express verbal communication, functional independent older adults (get ≥ 12 points from Barthel Index for Activities of Daily Living) and cognitive functional independent older adults (get \> 23 points from Thai Mental State Examination).
Primary Study Purpose

SCREENING

Blinding Strategy

NONE

The questionnaire is completed through by the 1st researcher and all clinical data collection will be recorded by the 2nd researcher.

Study Groups

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older adult

Subjects who has aged ≥ 60 years old.

Group Type EXPERIMENTAL

the association between periodontitis and malnutrition status

Intervention Type BEHAVIORAL

be determine the association between periodontitis and malnutrition status in older adult.

Interventions

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the association between periodontitis and malnutrition status

be determine the association between periodontitis and malnutrition status in older adult.

Intervention Type BEHAVIORAL

Eligibility Criteria

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Inclusion Criteria

1. Subjects who has aged ≥ 60 years old.
2. Subjects who not receive periodontal treatment within the previous 6 months.
3. Subjects who are able to read Thai and express verbal communication.
4. Subjects who are functional independent older adults (get ≥ 12 points from Barthel Index for Activities of Daily Living) \[50, 51\].
5. Subjects who are cognitive functional independent older adults (get \> 23 points from Thai Mental State Examination) \[52\].

Exclusion Criteria

1. Subjects with completely edentulous area.
2. Subjects who require antibiotic prophylaxis for dental examination
Minimum Eligible Age

60 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Mahidol University

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Kanyawat Rattanasuwan

Role: PRINCIPAL_INVESTIGATOR

Department of Oral Medicine and Periodontology, Faculty of Dentistry, Mahidol University.

Locations

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Kanyawat Rattanasuwan

Bangkok, , Thailand

Site Status

Countries

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Thailand

Other Identifiers

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MU-DT/PY-IRB 2019/051.1408

Identifier Type: -

Identifier Source: org_study_id