Effects of Coffee Roasting on Blood Sugar Levels in Healthy Humans
NCT ID: NCT05119153
Last Updated: 2021-11-12
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
NA
19 participants
INTERVENTIONAL
2019-11-05
2021-10-31
Brief Summary
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Detailed Description
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In part 1 (3 weeks), participants were randomly assigned to consume four beverages: a placebo containing water and caramel color, light, medium, or dark roast coffee before, during, or after consumption of a beverage containing 50 g of glucose.
In part 2 (3 weeks), participants were randomly assigned to consume four beverages: a placebo containing water and caramel color, light, medium, or dark roast coffee before, during, or after consumption of a standardized breakfast (corn flakes cereal + skim milk) containing 50 g of glucose.
In each part, fasting and postprandial glucose profiles were determined.
Conditions
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Keywords
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Study Design
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RANDOMIZED
CROSSOVER
BASIC_SCIENCE
SINGLE
Study Groups
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Placebo Comparator
Placebo composed of water and caramel color.
Placebo Comparator
Placebo designed to mimic coffee color.
Light Roasted Coffee
12 oz light roast coffee beverage prepared at 55 g ground coffee/L water
Light Roasted Coffee
12 oz light roast coffee
Medium Roasted Coffee
12 oz medium roast coffee beverage prepared at 55 g ground coffee/L water
Medium Roasted Coffee
12 oz medium roast coffee
Dark Roasted Coffee
12 oz dark roast coffee beverage prepared at 55 g ground coffee/L water
Dark Roasted Coffee
12 oz dark roast coffee
Interventions
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Placebo Comparator
Placebo designed to mimic coffee color.
Light Roasted Coffee
12 oz light roast coffee
Medium Roasted Coffee
12 oz medium roast coffee
Dark Roasted Coffee
12 oz dark roast coffee
Eligibility Criteria
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Inclusion Criteria
Exclusion Criteria
* Weight less than 110 pounds (55 kg)
* Pre-existing health conditions, such as:
* High cholesterol
* Hypertension
* Cardiovascular disease
* Gastrointestinal motility disorders
* Hypo- or hyperthyroidism
* Anemia
* Renal disease
* Liver disease, including hepatitis B or C, cholestasis, cirrhotic liver disease, or non-alcoholic fatty liver disease
* Chronic or acute pancreatitis
* Diabetes type 1 or 2
* Insulin resistance
* Polycystic ovary syndrome
* Food allergies or intolerances to coffee/caffeine/dairy/corn-based cereals.
* Currently taking prescription medication
* Current smoker
* Consumes more than 3 alcoholic beverages per day
* Pregnant or breastfeeding
* Not willing to take their own blood samples with finger sticks
18 Years
65 Years
ALL
Yes
Sponsors
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North Carolina State University
OTHER
Responsible Party
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Gabriel Keith Harris
Associate Professor of Food Science
Principal Investigators
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Gabriel K Harris, PhD
Role: PRINCIPAL_INVESTIGATOR
North Carolina State University
Locations
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Schaub Hall, Campus Box 7624
Raleigh, North Carolina, United States
Countries
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Other Identifiers
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16857
Identifier Type: -
Identifier Source: org_study_id