Genetic Study of Idiopathic Scoliosis in a Cohort of Families (SCOGEN)
NCT ID: NCT05116436
Last Updated: 2021-11-11
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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UNKNOWN
43 participants
OBSERVATIONAL
2020-06-06
2022-06-06
Brief Summary
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Detailed Description
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Conditions
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Study Design
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FAMILY_BASED
OTHER
Study Groups
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Patient with idiopathic scoliosis
Blood sample
It will test the presence or absence of genetic mutations found in other cohorts in previous studies.
Spine X-ray
To determine the scoliosis
Healthy related patients
Blood sample
It will test the presence or absence of genetic mutations found in other cohorts in previous studies.
Spine X-ray
To determine the scoliosis
Interventions
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Blood sample
It will test the presence or absence of genetic mutations found in other cohorts in previous studies.
Spine X-ray
To determine the scoliosis
Eligibility Criteria
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Inclusion Criteria
* Signed informed consent
* Affiliation to a social security scheme or beneficiary of such a scheme
* Be related to the first or second degree with at least 2 individuals suffering from idiopathic scoliosis, and whose family tree over 3 generations finds at least 3 cases of idiopathic scoliosis
* Do not present with scoliosis (clinical examination by an orthopedic doctor and x-rays of the spine).
* Affiliation to a social security scheme or beneficiary of such a scheme
* Be part of one of the following categories of vulnerable people: protected adults, adults unable to express their consent and not subject to a protection measure, pregnant women, parturients and nursing mothers, people deprived of their liberty, people hospitalized without consent, people admitted to a health or social establishment for purposes other than research
* Suspicion of scoliosis secondary to clinical examination
* Be part of one of the following categories of vulnerable people: protected adults, adults unable to express their consent and not subject to a protection measure, pregnant women, parturients and nursing mothers, people deprived of their liberty, people hospitalized without consent, people admitted to a health or social establishment for purposes other than research
* Discovery of scoliosis during research (if scoliosis of an idiopathic nature: patient included in the cohort of patients, if secondary scoliosis: exclusion from the family).
All patients :
Pregnancy in progress or desired with discontinuation of contraception (contraindication to the realization of x-rays).
18 Years
ALL
Yes
Sponsors
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European Clinical Trial Experts Network
OTHER
Ramsay Générale de Santé
OTHER
Responsible Party
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Locations
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Clinique Maussins-Nollet
Paris, , France
Countries
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Central Contacts
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Facility Contacts
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Jean-François Oudet
Role: primary
Marie-Hélène Barba
Role: backup
Other Identifiers
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2019-A03136-51
Identifier Type: -
Identifier Source: org_study_id