Prevalence of Mood and Anxiety Disorders in Adult Patients With Pulmonary Langerhans Cell Histiocytosis

NCT ID: NCT05114304

Last Updated: 2021-11-09

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Total Enrollment

100 participants

Study Classification

OBSERVATIONAL

Study Start Date

2021-11-30

Study Completion Date

2022-11-30

Brief Summary

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Pulmonary Langerhans cell histiocytosis (PLCH) is a rare disease, of unknown etiology, that occurs almost exclusively in smokers.The clinical experience suggests a high prevalence of anxiety symptoms and an addictive profile. However, no study to date has precisely investigated the prevalence of co-morbid psychiatric disorders in this population.The aim of the study is to evaluate the prevalence of co-morbid psychiatric disorders in adult PLCH patients.

This study should allow:

* to assess the prevalence of psychiatric disorders co-morbid in PLCH patients
* a targeted and more effective management of patients
* a better response rate to smoking and cannabis weaning, that represents a major goal for these patients.

Detailed Description

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Conditions

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Pulmonary Langerhans Cell Histiocytosis

Study Design

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Observational Model Type

OTHER

Study Time Perspective

CROSS_SECTIONAL

Study Groups

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Pulmonary Langerhans cell histiocytosis (PLCH)

Adults with pulmonary Langerhans cell histiocytosis

Evaluation of co-morbid psychiatric disorders

Intervention Type OTHER

Added scales :

* Mini Internationnal Neuropsychiatric Interview
* Fagerström test
* DSM-5 Scale

Additional dosage : - a urine sample will be taken to evaluate the presence of tobacco and nicotine breakdown products and the presence of various toxics

Expired carbon monoxide for patients using nicotine substitutes

Interventions

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Evaluation of co-morbid psychiatric disorders

Added scales :

* Mini Internationnal Neuropsychiatric Interview
* Fagerström test
* DSM-5 Scale

Additional dosage : - a urine sample will be taken to evaluate the presence of tobacco and nicotine breakdown products and the presence of various toxics

Expired carbon monoxide for patients using nicotine substitutes

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* Patients of 18 years of age or older with PLCH diagnosed at adulthood
* Patients affiliated to the French Health Care System
* Informed patients

Exclusion Criteria

* Patient unable to understand the interview (language barrier)
* Patient under guardianship or curatorship
* Patient under AME (French medical help for foreigners)
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Assistance Publique - Hôpitaux de Paris

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Locations

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Hôpital Saint-Louis, Centre de référence national des histiocytoses, Service de Pneumologie

Paris, , France

Site Status

Countries

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France

Central Contacts

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Abdellatif TAZI

Role: CONTACT

Phone: +33142499618

Email: [email protected]

Matthieu Resche-Rigon, Pr

Role: CONTACT

Phone: +33142499742

Email: [email protected]

Facility Contacts

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Abdellatif TAZI

Role: primary

Other Identifiers

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APHP210292

Identifier Type: -

Identifier Source: org_study_id