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Surgical Treatment of Hepatic Hydatidosis in Elderly Patients

NCT ID: NCT05113550

Last Updated: 2021-11-16

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

279 participants

Study Classification

OBSERVATIONAL

Study Start Date

2021-01-01

Study Completion Date

2021-09-30

Brief Summary

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Cystic echinococcosis is a clinically complex chronic parasitic disease and a major socioeconomic problem in endemic areas. The safety of liver resection in elderly patients is often debated among medical professionals. The investigators analyzed the postoperative morbidity and mortality rates of elderly patients who underwent surgery at our unit.

Detailed Description

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Retrospective observational study from prospective database focused on liver hydatidosis carried out at our Hepato-Pancreato-Biliary Surgery Unit. The study period spanned from January 2006 to October 2020. The study was approved by the Research Ethics Committee of our hospital. An informed consent from the patient was not required since the study was retrospective and observational, and entailed no risk. Seventy years of age was the cutoff age to consider patients as elderly.

Inclusion criteria of patients: liver hydatid cyst (LHC) diagnosed by preoperative computed tomography (CT) or magnetic resonance imaging (MRI) and pathological diagnosis after surgery, and LHC treated by total or partial pericystectomy.

Exclusion criteria of patients: emergency surgery and simple drainage of cyst.

Conditions

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Cystic Echinococcosis

Study Design

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Observational Model Type

CASE_CONTROL

Study Time Perspective

RETROSPECTIVE

Study Groups

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Young group

patients \< 70 years of age

Surgical remove

Intervention Type OTHER

liver hydatid cyst (LHC) treated by total or partial pericystectomy

Elderly

Patients ≥ 70 years of age)

Surgical remove

Intervention Type OTHER

liver hydatid cyst (LHC) treated by total or partial pericystectomy

Interventions

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Surgical remove

liver hydatid cyst (LHC) treated by total or partial pericystectomy

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* liver hydatid cyst (LHC)
* pathological diagnosis after surgery
* LHC treated by total or partial pericystectomy

Exclusion Criteria

* emergency surgery and simple drainage of cyst
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Universidad de Extremadura

OTHER

Sponsor Role lead

Responsible Party

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Gerardo Blanco-Fernández

Profesor

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Gerardo Blanco-Fernández, MD, PhD

Role: PRINCIPAL_INVESTIGATOR

University of Extremadura

Locations

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Universidad de Extremadura- Facultad de Medicina

Badajoz, , Spain

Site Status

Gerardo Blanco-Fernández

Badajoz, , Spain

Site Status

Countries

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Spain

References

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Mihmanli M, Idiz UO, Kaya C, Demir U, Bostanci O, Omeroglu S, Bozkurt E. Current status of diagnosis and treatment of hepatic echinococcosis. World J Hepatol. 2016 Oct 8;8(28):1169-1181. doi: 10.4254/wjh.v8.i28.1169.

Reference Type BACKGROUND
PMID: 27729953 (View on PubMed)

Adamina M, Guller U, Weber WP, Oertli D. Propensity scores and the surgeon. Br J Surg. 2006 Apr;93(4):389-94. doi: 10.1002/bjs.5265.

Reference Type BACKGROUND
PMID: 16400708 (View on PubMed)

Jaen-Torrejimeno I, Lopez-Guerra D, Prada-Villaverde A, Blanco-Fernandez G. Pattern of Relapse in Hepatic Hydatidosis: Analysis of 238 Cases in a Single Hospital. J Gastrointest Surg. 2020 Feb;24(2):361-367. doi: 10.1007/s11605-019-04163-7. Epub 2019 Feb 26.

Reference Type BACKGROUND
PMID: 30809783 (View on PubMed)

Jaen-Torrejimeno I, Latorre-Fragua R, Lopez-Guerra D, Rojas-Holguin A, Manuel-Vazquez A, Blanco-Fernandez G, Ramia JM. Jaundice as a clinical presentation in liver hydatidosis increases the risk of postoperative biliary fistula. Langenbecks Arch Surg. 2021 Jun;406(4):1139-1147. doi: 10.1007/s00423-020-02070-z. Epub 2021 Jan 2.

Reference Type BACKGROUND
PMID: 33389115 (View on PubMed)

Muhtarov M, Rainova I, Tamarozzi F. Treatment of Hepatic Cystic Echinococcosis in Patients from the Southeastern Rhodope Region of Bulgaria in 2004-2013: Comparison of Current Practices with Expert Recommendations. Am J Trop Med Hyg. 2016 Apr;94(4):900-5. doi: 10.4269/ajtmh.15-0620. Epub 2016 Feb 1.

Reference Type RESULT
PMID: 26834196 (View on PubMed)

Other Identifiers

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HUB-2021-01

Identifier Type: -

Identifier Source: org_study_id