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Inflammatory Markers: HOLEP Versus TURP

NCT ID: NCT05108662

Last Updated: 2021-11-05

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

50 participants

Study Classification

INTERVENTIONAL

Study Start Date

2020-02-01

Study Completion Date

2021-08-30

Brief Summary

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Aim of the study is to compare the systemic inflammatory markers and surgical stress response in patients undergoing HOLEP or TUR-P surgery.

Detailed Description

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Benign prostatic hyperplasia (BPH) is the most common disease in aging men worldwide, causing significant difficulties and resulting in bladder outlet obstruction. Basically, surgical techniques in patients with BPH are transurethral resection of the prostate (TURP), holmium laser enucleation of the prostate (HOLEP), and open prostoactemy surgery. There are many studies comparing the clinical outcomes of TURP and HOLEP surgery. However, to the best of our knowledge, there has not been a study comparing the effects of these two types of surgery on inflammatory markers and stress hormones.

Conditions

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Prostate Hyperplasia

Study Design

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Allocation Method

NON_RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

OTHER

Blinding Strategy

NONE

Study Groups

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HOLEP

Patients with a prostate volume greater than 80 g

Group Type ACTIVE_COMPARATOR

Surgery method

Intervention Type PROCEDURE

Patients were subdivided into two groups according to their prostate volume

TURP

Patients with a prostate volume less than 80 g

Group Type ACTIVE_COMPARATOR

Surgery method

Intervention Type PROCEDURE

Patients were subdivided into two groups according to their prostate volume

Interventions

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Surgery method

Patients were subdivided into two groups according to their prostate volume

Intervention Type PROCEDURE

Eligibility Criteria

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Inclusion Criteria

* ASA scores I-III patients
* having benign prostatic hyperplasia
* undergoing HOLEP or TURP surgery under general anesthesia

Exclusion Criteria

* immune system disease,
* diabetes mellitus,
* malignancy other than prostate disease,
* history of steroid use,
Eligible Sex

MALE

Accepts Healthy Volunteers

No

Sponsors

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Adana City Training and Research Hospital

OTHER

Sponsor Role lead

Responsible Party

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Baris Arslan, MD

Baris Arslan, MD, Principal investigator

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Baris Arslan, MD

Role: PRINCIPAL_INVESTIGATOR

Adana City Training and Research Hospital

Locations

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Adana City Training and Research Hospital

Adana, , Turkey (Türkiye)

Site Status

Countries

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Turkey (Türkiye)

Other Identifiers

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49-708

Identifier Type: -

Identifier Source: org_study_id