The Effect of Self-rehabilitation Using Communication APP After Arthroscopic Surgery for Rotator Cuff Tear

NCT ID: NCT05102968

Last Updated: 2021-11-02

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Clinical Phase

NA

Total Enrollment

60 participants

Study Classification

INTERVENTIONAL

Study Start Date

2019-03-22

Study Completion Date

2026-12-31

Brief Summary

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The purpose of this study was to assess the clinical effect of a mobile application supporting home-based rehabilitation for the patients after arthroscopic rotator cuff repair. The investigators hypothesized the clinical results of the patients using a mobile application (APP) to support the home-based rehabilitation were comparable to the patients receiving the supervised rehabilitation.

This prospective randomized case-control study was approved by the institutional review board of the Kaohsiung Veteran General Hospital (IRB No. KSVGH18-CT12-15) prior to enroll any patients. Patients were recruited if they had a small to medium-sized full-thickness rotator cuff tear or, a Lafosse type II or III subscapularis tear diagnosed and then repaired under shoulder arthroscope. After the surgery, patients were randomized either to the home-based rehabilitation (the home group) or the hospital supervised rehabilitation (the supervised group).

In the home group, patients self-managed rehabilitation exercise without supervision. Rehabilitation were supportive with the APP. Patient could communicate with the physician via the APP. In the supervised group, patients attended one-on-one instructions with therapists and exercised under supervision at hospital.

Patients' characters were recorded. Peri-operative factors associated with rotator cuff healing were assessed. The active ROM (forward elevation, abduction, external and internal rotation), the visual analogue scale (VAS) pain scores, the American shoulder and elbow surgeon shoulder (ASES) scores and the modified Constant scores were recorded pre-operatively and post-operatively 3, 6, 12 and 24 months. The isometric shoulder strength was assessed with the hand-held dynamometer. The compliance of post-operative rehabilitation was evaluated not only from patients' self-reported logs but also by physicians at post-operatively 6, 12 and 24 weeks. Tendon integrity was evaluated with MRI scan at least 6 months after the index surgery. In the pilot study, we found a mean difference of 4 points and a standard deviation of 5.5 points in the modified Constant scores. Power analysis revealed a total sample size of 62 patients (31 patients in each group) would achieve a statistical power of 0.8 with a two-tailed level of 0.05 to detect significant differences. Statistical level of significance was defined as p\<0.05.

Detailed Description

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Introduction- Arthroscopic repair in the treatment of rotator cuff tear had been accepted wildly. It had been demonstrated that surgical management improved life quality and reduced economic burdens. However, joint stiffness and cuff re-tear, the two most common complications after arthroscopic cuff repair were concerned. Post-operative rehabilitation and its compliance are crucial for resilience. For rehabilitation, performing exercise too slowly caused joint stiffness, but too aggressively increased the risk of cuff re-tear. To prevent these complications, supervised physical therapy was advised after rotator cuff repair. However, the associated cost of rehabilitation under supervision exacerbated patients' financial burden. Home-based rehabilitation had been proposed and employed wildly, such as for the cardiopulmonary function after coronary artery disease, the ambulation training after joint replacement and the muscle strengthening after ACL reconstruction. In the conservative treatment of frozen shoulder and rotator cuff tear, patients with home-based physical therapy obtained comparable outcomes to supervised physical therapy. After arthroscopic rotator cuff repair, the clinical benefit of home-based rehabilitation was still controversial. In previous studies, supervised rehabilitation was not superior to home-based rehabilitation in long-term functional outcomes. However, some authors considered that the rehabilitation under supervision reduced the risk of cuff re-tear and joint stiffness. Furthermore, the patients who received the home-based rehabilitation supporting with a booklet or videotape had inferior compliance. For resolving the above-mentioned problems, supporting with a mobile application was possibly an alternative. It is a trend nowadays that telerehabilitation was assisted with mobile applications, such as for patients with stroke, spinal cord injury and musculoskeletal trauma. There was still lack of the literature about such rehabilitation method for the patients after arthroscopic rotator cuff repair. The purpose of this study was to assess the clinical effect of a mobile application supporting home-based rehabilitation for the patients after arthroscopic rotator cuff repair. The investigators hypothesized the clinical results of the patients using a mobile application to support the home-based rehabilitation were comparable to the patients receiving the supervised rehabilitation.

Patients Registries- This prospective randomized case-control study was approved by the institutional review board of the Kaohsiung Veteran General Hospital (IRB No. KSVGH18-CT12-15) prior to enroll any patients. Eligible patients were determined by the attending surgeon. After the surgery, a research assistant conducted the informed consent process before the enrollment in the study. Subjects were randomized either to the home-based rehabilitation (the home group) or the hospital supervised rehabilitation (the supervised group). Each patient was assigned a study number in a consecutive sequence. A randomization sequence using two variables was determined by the mobile application. The allocation of two rehabilitation modes according to the randomization sequence was designated to each subject in a sealed envelope. The therapist opened envelopes at the 1st day post-operatively.

Surgical procedures- Arthroscopic rotator cuff repair for all patients were performed by a single senior surgeon (F.H) at Kaohsiung Veteran General Hospital. Under general anesthesia, patients sit on the beach-chair. The posterior, posterolateral, lateral, and anterolateral portals were created. Intra-articular lesions including subscapularis and biceps long-head tendon were evaluated via the posterior viewing portal. For a Lafosse type II or III tear, subscapularis was repaired with one or two anchors under posterior visualization. Tenotomy, tenodesis or labrum repair for biceps lesions was performed according to labrum tear pattern, age, and functional demand. Rotator cuff lesion was addressed while viewing from the lateral portal. The dimension of involved cuff from anterior to posterior was measured with a probe. Single- or double-row repair was performed based on tear size and pattern. Acromioplasty or partial distal clavicle resection was performed if indicated.

Rehabilitation protocol- All patients received the one standard rehabilitation protocol and used the booklet that described the rehabilitation exercise in detail. The 6-month rehabilitation protocol consisted of four stages. The first stage was the immobilization phase that patients wear the arm sling for 2-4 weeks. The second stage was the ROM phase that patients started from passive to assisted-active ROM for 4-6 weeks. The third stage was the low-tensity training phase that patients allowed active ROM and isokinetic elastic-band exercise for 4-8 weeks. The fourth stage was the joint stabilization phase that patients focused on training the muscle for scapular stabilization and continued isokinetic exercise at least 2 months post-operatively. All patients were follow-up in the clinic every 4-6 weeks after the surgery. After the clinical visit, they were instructed by therapists to perform exercise at home while proceeding the next rehabilitation stage. The exercise program was adjusted according to the recovery status of each patient.

Intervention- In the home group, patients managed rehabilitation exercise by themselves after the surgery without supervision. Rehabilitation protocol and exercise instruction video were available in the APP. Patient could communicate with the physician and therapist via the APP. In the supervised group, subjects attended one-on-one instructions with a therapist (once a week at post-operative 2nd\~12th week and once two weeks at post-operative 13th\~24th week; totally 16 sessions in the 6-month rehabilitation program) and exercised under supervision at hospital. Subjects would receive additional sessions based on the rehabilitation progress. Subjects could cancel scheduled sessions by personal reasons. We provided telephone consultation without APP communication for subjects in the supervised group.

Outcome evaluation- Patients characters including age, sex, body mass index, arm dominance, trauma history, education background and functional demand were recorded. Peri-operative factors associated with rotator cuff healing were assessed. The active ROM (forward elevation, abduction, external and internal rotation), the visual analogue scale (VAS) pain scores, the American shoulder and elbow surgeon shoulder (ASES) scores and the modified Constant scores were recorded by a research assistant preoperatively and post-operatively 3, 6, 12 and 24 months. Biceps, subscapularis, infraspinatus, and supraspinatus index were measured post-operatively 3, 6, 12 and 24 months. The compliance of post-operative rehabilitation was assessed at post-operatively 6, 12 and 24 weeks. Tendon integrity was evaluated with MRI scan (a 1.5-T unit) at least 6 months after the surgery.

Sample size analysis and statistics methods- In the pilot study, the investigators found a mean difference of 4 points and a standard deviation of 5.5 points in the modified Constant scores. Power analysis revealed a total sample size of 62 patients (31 patients in each group) would achieve a statistical power of 0.8 with a two-tailed level of 0.05 to detect significant differences. All statistical analyses were performed using the SPSS (version 23; IBM, Armonk, NY). Categorical data between groups were compared with the Pearson's chi-squared test or Fisher's exact test. Comparisons of normally distributed continuous data with the independent t-test and non-normally distributed continuous data with the rank sum test were performed. The analysis of covariance was used to compare the subjective scores (the VAS pain scores, ASES scores and modified Constant scores) and objective outcomes (active ROM and muscle index) between two groups. Statistical level of significance was defined as p\<0.05.

Conditions

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Rotator Cuff Tears

Keywords

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Rotator cuff tear Arthroscopic surgery Telerehabilitation

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

SINGLE

Outcome Assessors

Study Groups

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Rehabilitation with mobile application

Patients self-managed rehab exercise with a supportive mobile application

Group Type ACTIVE_COMPARATOR

Home-based rehabilitation supporting with the mobile application

Intervention Type BEHAVIORAL

For patients with mobile application supportive rehabilitation, patients managed rehabilitation exercise by themselves after the surgery without supervision. Rehabilitation protocol and exercise instruction video were available in the application. Patient could communicate with the physician and therapist via the application.

Rehabilitation under supervision

Patients received supervised physical therapy

Group Type ACTIVE_COMPARATOR

Supervised rehabilitation by the therapist

Intervention Type BEHAVIORAL

For patients with therapist supervised rehabilitation, patients attended one-on-one instructions with a therapist (once a week at post-operative 2nd\~12th week and once two weeks at post-operative 13th\~24th week; totally 16 sessions in the 6-month rehabilitation program) and exercised under supervision at hospital. Subjects would receive additional sessions based on the rehabilitation progress. Subjects could cancel scheduled sessions by personal reasons. We provided telephone consultation without APP communication for subjects in the supervised group.

Interventions

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Supervised rehabilitation by the therapist

For patients with therapist supervised rehabilitation, patients attended one-on-one instructions with a therapist (once a week at post-operative 2nd\~12th week and once two weeks at post-operative 13th\~24th week; totally 16 sessions in the 6-month rehabilitation program) and exercised under supervision at hospital. Subjects would receive additional sessions based on the rehabilitation progress. Subjects could cancel scheduled sessions by personal reasons. We provided telephone consultation without APP communication for subjects in the supervised group.

Intervention Type BEHAVIORAL

Home-based rehabilitation supporting with the mobile application

For patients with mobile application supportive rehabilitation, patients managed rehabilitation exercise by themselves after the surgery without supervision. Rehabilitation protocol and exercise instruction video were available in the application. Patient could communicate with the physician and therapist via the application.

Intervention Type BEHAVIORAL

Other Intervention Names

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Home exercise Supervised exercise

Eligibility Criteria

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Inclusion Criteria

* patients had a small to medium-sized (less than 3 cm) full-thickness rotator cuff tear or, a Lafosse type II or III subscapularis tear diagnosed and repaired by shoulder arthroscope
* patients were willing to consent to post-operative rehabilitation randomization and commit to the two-year clinical follow-up period.

Exclusion Criteria

* pre-operative shoulder stiffness (defined as passive forward elevation less than 100 degrees and external rotation loss over 50% comparing to the contralateral side)
* an intra-operative irreparable cuff tear
* a prior ipsilateral shoulder surgery
* a history of systemic auto-immune disease or septic arthritis of the ipsilateral shoulder
Minimum Eligible Age

20 Years

Maximum Eligible Age

70 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Kaohsiung Veterans General Hospital.

OTHER

Sponsor Role lead

Responsible Party

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Futing Huang

Principal Investigator

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Linda Lin, PhD

Role: STUDY_DIRECTOR

Institute of Physical education, Health & Leisure Studies, National Cheng Kung University

Locations

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Kaohsiung Veterns General Hospital

Kaohsiung City, , Taiwan

Site Status RECRUITING

Countries

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Taiwan

Central Contacts

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Futing Huang, MD

Role: CONTACT

Phone: 886-910775551

Email: [email protected]

Facility Contacts

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Futing Huang, MD

Role: primary

References

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Denard PJ, Ladermann A, Burkhart SS. Prevention and management of stiffness after arthroscopic rotator cuff repair: systematic review and implications for rotator cuff healing. Arthroscopy. 2011 Jun;27(6):842-8. doi: 10.1016/j.arthro.2011.01.013.

Reference Type BACKGROUND
PMID: 21624680 (View on PubMed)

Thigpen CA, Shaffer MA, Gaunt BW, Leggin BG, Williams GR, Wilcox RB 3rd. The American Society of Shoulder and Elbow Therapists' consensus statement on rehabilitation following arthroscopic rotator cuff repair. J Shoulder Elbow Surg. 2016 Apr;25(4):521-35. doi: 10.1016/j.jse.2015.12.018.

Reference Type BACKGROUND
PMID: 26995456 (View on PubMed)

Ross D, Maerz T, Lynch J, Norris S, Baker K, Anderson K. Rehabilitation following arthroscopic rotator cuff repair: a review of current literature. J Am Acad Orthop Surg. 2014 Jan;22(1):1-9. doi: 10.5435/JAAOS-22-01-1.

Reference Type BACKGROUND
PMID: 24382874 (View on PubMed)

Taylor RS, Brown A, Ebrahim S, Jolliffe J, Noorani H, Rees K, Skidmore B, Stone JA, Thompson DR, Oldridge N. Exercise-based rehabilitation for patients with coronary heart disease: systematic review and meta-analysis of randomized controlled trials. Am J Med. 2004 May 15;116(10):682-92. doi: 10.1016/j.amjmed.2004.01.009.

Reference Type BACKGROUND
PMID: 15121495 (View on PubMed)

Ramey L, Osborne C, Kasitinon D, Juengst S. Apps and Mobile Health Technology in Rehabilitation: The Good, the Bad, and the Unknown. Phys Med Rehabil Clin N Am. 2019 May;30(2):485-497. doi: 10.1016/j.pmr.2018.12.001. Epub 2019 Mar 5.

Reference Type BACKGROUND
PMID: 30954161 (View on PubMed)

Pires IM, Marques G, Garcia NM, Florez-Revuelta F, Ponciano V, Oniani S. A Research on the Classification and Applicability of the Mobile Health Applications. J Pers Med. 2020 Feb 27;10(1):11. doi: 10.3390/jpm10010011.

Reference Type BACKGROUND
PMID: 32120849 (View on PubMed)

Alenabi T, Jackson M, Tetreault P, Begon M. Electromyographic activity in the immobilized shoulder musculature during ipsilateral elbow, wrist, and finger movements while wearing a shoulder orthosis. J Shoulder Elbow Surg. 2013 Oct;22(10):1400-7. doi: 10.1016/j.jse.2013.04.007. Epub 2013 Jun 14.

Reference Type BACKGROUND
PMID: 23770113 (View on PubMed)

Cools AM, Dewitte V, Lanszweert F, Notebaert D, Roets A, Soetens B, Cagnie B, Witvrouw EE. Rehabilitation of scapular muscle balance: which exercises to prescribe? Am J Sports Med. 2007 Oct;35(10):1744-51. doi: 10.1177/0363546507303560. Epub 2007 Jul 2.

Reference Type BACKGROUND
PMID: 17606671 (View on PubMed)

Richards RR, An KN, Bigliani LU, Friedman RJ, Gartsman GM, Gristina AG, Iannotti JP, Mow VC, Sidles JA, Zuckerman JD. A standardized method for the assessment of shoulder function. J Shoulder Elbow Surg. 1994 Nov;3(6):347-52. doi: 10.1016/S1058-2746(09)80019-0. Epub 2009 Feb 13.

Reference Type BACKGROUND
PMID: 22958838 (View on PubMed)

Katolik LI, Romeo AA, Cole BJ, Verma NN, Hayden JK, Bach BR. Normalization of the Constant score. J Shoulder Elbow Surg. 2005 May-Jun;14(3):279-85. doi: 10.1016/j.jse.2004.10.009.

Reference Type BACKGROUND
PMID: 15889027 (View on PubMed)

Holmgren T, Oberg B, Sjoberg I, Johansson K. Supervised strengthening exercises versus home-based movement exercises after arthroscopic acromioplasty: a randomized clinical trial. J Rehabil Med. 2012 Jan;44(1):12-8. doi: 10.2340/16501977-0889.

Reference Type BACKGROUND
PMID: 22124602 (View on PubMed)

Buker N, Akkaya S, Akkaya N, Gokalp O, Kavlak E, Ok N, Kiter AE, Kitis A. Comparison of effects of supervised physiotherapy and a standardized home program on functional status in patients with total knee arthroplasty: a prospective study. J Phys Ther Sci. 2014 Oct;26(10):1531-6. doi: 10.1589/jpts.26.1531. Epub 2014 Oct 28.

Reference Type RESULT
PMID: 25364104 (View on PubMed)

Grant JA, Mohtadi NG. Two- to 4-year follow-up to a comparison of home versus physical therapy-supervised rehabilitation programs after anterior cruciate ligament reconstruction. Am J Sports Med. 2010 Jul;38(7):1389-94. doi: 10.1177/0363546509359763. Epub 2010 Apr 1.

Reference Type RESULT
PMID: 20360607 (View on PubMed)

Krischak G, Gebhard F, Reichel H, Friemert B, Schneider F, Fisser C, Kaluscha R, Kraus M. A prospective randomized controlled trial comparing occupational therapy with home-based exercises in conservative treatment of rotator cuff tears. J Shoulder Elbow Surg. 2013 Sep;22(9):1173-9. doi: 10.1016/j.jse.2013.01.008. Epub 2013 Mar 22.

Reference Type RESULT
PMID: 23523073 (View on PubMed)

Roddey TS, Olson SL, Gartsman GM, Hanten WP, Cook KF. A randomized controlled trial comparing 2 instructional approaches to home exercise instruction following arthroscopic full-thickness rotator cuff repair surgery. J Orthop Sports Phys Ther. 2002 Nov;32(11):548-59. doi: 10.2519/jospt.2002.32.11.548.

Reference Type RESULT
PMID: 12449254 (View on PubMed)

Lisinski P, Huber J, Wilkosz P, Witkowska A, Wytrazek M, Samborski W, Zagloba A. Supervised versus uncontrolled rehabilitation of patients after rotator cuff repair-clinical and neurophysiological comparative study. Int J Artif Organs. 2012 Jan;35(1):45-54. doi: 10.5301/ijao.5000037.

Reference Type RESULT
PMID: 22287203 (View on PubMed)

Song SJ, Jeong TH, Moon JW, Park HV, Lee SY, Koh KH. Short-term Comparison of Supervised Rehabilitation and Home-based Rehabilitation for Earlier Recovery of Shoulder Motion, Pain, and Function after Rotator Cuff Repair. Clin Shoulder Elb. 2018 Mar 1;21(1):15-21. doi: 10.5397/cise.2018.21.1.15. eCollection 2018 Mar.

Reference Type RESULT
PMID: 33330146 (View on PubMed)

Other Identifiers

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VGHKS 18-CT12-15

Identifier Type: -

Identifier Source: org_study_id