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Healing Assessment of Osseous Defects After Surgical Removal of Periapical Lesions

NCT ID: NCT05100615

Last Updated: 2021-10-29

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Clinical Phase

NA

Total Enrollment

24 participants

Study Classification

INTERVENTIONAL

Study Start Date

2021-11-30

Study Completion Date

2022-05-31

Brief Summary

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recruited patients with periapical lesions will be divided into three groups and surgically treated with three types of bone graft (hydroxyappatite, nanohydroxyappatite and PRF WITH NANOHYDROXTAPPATITE) and then evaluated for month, three months and six months for the healing of periapical bone

Detailed Description

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Conditions

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Effects of the Elements

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

DOUBLE

Participants Outcome Assessors

Study Groups

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hydroxyappatite

hydroxyapatite powder used for enhancement of bone regeneration

Group Type OTHER

surgery

Intervention Type PROCEDURE

applying the graft inside bony defect after surgery

nanohydroxyapatite

nanohydroxyapatite powder used for enhancement of bone regeneration

Group Type OTHER

surgery

Intervention Type PROCEDURE

applying the graft inside bony defect after surgery

PRF with nanohydroxyapatite

platelet rich fibrin mixed with nanohydroxyapatite used for enhancement of bone regeneration

Group Type OTHER

surgery

Intervention Type PROCEDURE

applying the graft inside bony defect after surgery

Interventions

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surgery

applying the graft inside bony defect after surgery

Intervention Type PROCEDURE

Eligibility Criteria

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Inclusion Criteria

* The patient will be in range of 20-45 years of age at the time of treatment, having periapical lesions starting from 5mm or more in diameter related to failed endodontically treated single canaled teeth.

Exclusion Criteria

* Any systemic debilitating disease such as:

Diabetes mellitus, renal disease, Liver disease or liver failure, Rheumatoid arthritis, Neoplastic disease or its treatment, chronic corticosteroid therapy, chronic hepatitis B or C , History of hepatitis A, pregnant females.
Minimum Eligible Age

20 Years

Maximum Eligible Age

45 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Minia University

OTHER

Sponsor Role lead

Responsible Party

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Amira mohammed elkholly

phD student- Endodontic Departement

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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Amira mohammed fathy Elkholly

Cairo, , Egypt

Site Status RECRUITING

Countries

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Egypt

Central Contacts

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Amira Elkholly, PHD

Role: CONTACT

Phone: +201001902507

Email: [email protected]

Reham Hassan, Ass.prof

Role: CONTACT

Phone: +201001542529

Email: [email protected]

Facility Contacts

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Amira Elkholly, PHD

Role: primary

Reham Hassan, Ass.prof

Role: backup

Other Identifiers

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238

Identifier Type: -

Identifier Source: org_study_id